【产品介绍】：

生物活性：Toxoflavin-13C4 is the 13C-labeled Toxoflavin. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2]. Antibiotic properties.
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Toxoflavin-13C4 相关抗体:
Beta-Catenin Antibody
TCF7L2/TCF4 Antibody
MRP2 Antibody
beta Catenin Antibody (YA936)
beta Catenin Antibody (YA938)
Elongation factor 2 Antibody (YA962)
Elongation factor 2 Antibody (YA964)
Phospho-delta 1 Catenin (Ser268) Antibody (YA1019)
PU.1/SPI1 Antibody (YA1116)
Phospho-beta Catenin (Ser33/Ser37) Antibody (YA3096)
gamma Catenin Antibody
Sulfadimidine Antibody (YA906)
beta Catenin Antibody (YA937)
Elongation factor 2 Antibody (YA963)
Phospho-delta 1 Catenin (Tyr228) Antibody (YA1018)
Phospho-delta 1 Catenin (Thr916) Antibody (YA1020)
Anthrax Protective gen Antibody (YA1060)
Elongation factor 1 gamma Antibody (YA2004)
Pulmonary Surfactant Associated Protein D Antibody (YA2107)
Cathelicidin Antibody (YA2380)
Elongation Factor Ts Antibody (YA2524)
Elongation Factor 1A2 Antibody (YA2879)
BPI Antibody (YA3068)
MetRS Antibody (YA3196)
分子量：196.13
Formula：C313C4H6N5O2
CAS 号：2300178-70-3
非标记 CAS：84-82-2
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (533 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
 [Content Brief]
[2]. Wei W, et al. Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo. Int J Cancer. 2010 May 15;126(10):2426-36.
 [Content Brief]
[3]. Franci G, et al. Identification and characterization of PKF118-310 as a KDM4A inhibitor. Epigenetics. 2017 Mar 4;12(3):198-205.
 [Content Brief]