「同位素标记抑制剂」Butamben-d9
【产品介绍】:
生物活性:Butamben-d9 is the deuterium labeled Butamben. Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions[1][2].
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Butamben-d9 相关抗体:
Annexin VI Antibody
xCT Antibody (YA006)
Calbindin Antibody
Calreticulin Antibody
xCT Antibody (YA652)
ATP1A1 Antibody
Cardiac Troponin I/TNNC1 Antibody
Alpha-ENaC Antibody
SCGN Antibody (YA1167)
RAMP1 Antibody (YA1818)
Annexin V Antibody (YA1829)
Striatin 4 Antibody (YA2088)
Fibulin 5 Antibody (YA2448)
RASGRP1 Antibody (YA2546)
Fibulin 1 Antibody (YA2831)
EFEMP1 Antibody (YA2883)
LGI1 Antibody (YA2885)
CRCP Antibody (YA3350)
CRMP2 Antibody (YA3370)
Annexin VII Antibody (YA1138)
Parvalbumin Antibody (YA1249)
SLC12A1 Antibody (YA1403)
Annexin IV Antibody (YA1921)
SERCA2 ATPase Antibody (YA1931)
CRMP1 Antibody (YA1941)
Stromal Interaction Molecule 1 Antibody (YA2092)
Cardiac Troponin C Antibody (YA2125)
SERCA1 ATPase Antibody (YA2157)
TrpV5 Antibody (YA2284)
NCX1 Antibody (YA2331)
分子量:202.30
Formula:C11H6D9NO2
非标记 CAS:94-25-7
中文名称:对氨基苯甲酸丁酯 d9
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (526 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Cereda CM, et al. Liposomal butamben gel formulations: toxicity assays and topical anesthesia in an animal model. J Liposome Res. 2017 Mar;27(1):74-82.
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[3]. Rampaart LJA, et, al. The local anesthetic butamben inhibits total and L-type barium currents in PC12 cells. Anesth Analg. 2008 Jun;106(6):1778-83.
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[4]. Berg RJV, et, al. The local anesthetic n-butyl-p-aminobenzoate selectively affects inactivation of fast sodium currents in cultured rat sensory neurons. Anesthesiology. 1995 Jun;82(6):1463-73.
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[5]. Kolesnikov YA, et, al. Analgesic synergy between topical morphine and butamben in mice. Anesth Analg. 2003 Oct;97(4):1103-7, table of contents.
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