「同位素标记抑制剂」CAS:1131996-12-7|Apixaban-d3
【产品介绍】:
生物活性:Apixaban-d3 (BMS-562247-01-d3) is the deuterium labeled Apixaban (HY-50667)[1]. Apixaban (BMS-562247-01) is a highly selective, reversible and orally active inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively[2]. Apixaban is in development for the prevention and treatment of various thromboembolic diseases[3].
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Apixaban-d3 相关抗体:
Antithrombin III Antibody (YA3352)
分子量:462.52
Formula:C25H22D3N5O4
CAS 号:1131996-12-7
非标记 CAS:503612-47-3
性状:固体
颜色:Off-white to light yellow
中文名称:阿哌沙班-d3
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years,4°C:2 years
In solvent:-80°C:6 months,-20°C:1 month