德尔塔
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「同位素标记抑制剂」Sacubitril-d4

发布时间:2025-05-29     作者:德尔塔生物   分享到:

【产品介绍】:

生物活性:Sacubitril-d4 is the deuterium labeled Sacubitril. Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696.
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量:415.52
Formula:C24H25D4NO5
CAS 号:1884269-07-1
非标记 CAS:149709-62-6
性状:固体
颜色:White to off-white
中文名称:沙库必曲 d4
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)