【产品介绍】：

Streptomycin sulfate is an aminocyclitol glycoside antibiotic which interferes with protein synthesis in prokaryotes. This antibiotic is effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media. Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit at the S12 protein thereby inducing a misreading of the genetic code, inhibiting the initiation of translation of DNA which then results in death for a susceptible bacterium.An antibiotic for cell culture. 安全信息 标识符号 GHS08, GHS07 危害声明 H302,H361 警示性声明 P280,P308+P313,P330,P301+P312 RTECS WK4990000 WGK 3 属性 产品名称 硫酸链霉素 产品名称 Streptomycin sulfate 别名 硫酸链霉素;链霉素硫酸盐;链霉素 英文别名 Streptomycin sulphate streptomycin, sulfate CAS编号 3810-74-0 分子式 C42H84N14O36S3 分子量 1457.38 PubChem CID 19648 MDL号 MFCD00037023 Beilstein 3894995 EC号 223-286-0 Merck Index 8826 规格或纯度 720 I.U./mg 应用 An antibiotic for cell culture. 生化机理 Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation. Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. 熔点 250 °C 比旋光度 -85° (C=1,H2O) 溶解性 Soluble in water (50 mg/ml). 储存温度 2-8°C储存 运输条件 冰袋运输 密度 0.873