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维库溴铵是一种非偏振神经肌肉松弛剂。A nonpolarizing neuromuscular relaxant 安全信息 标识符号 GHS07 危害声明 H302 RTECS TN4875000 WGK 3 属性 产品名称 维库溴铵 水合物 产品名称 Vecuronium Bromide 别名 维库溴铵 英文别名 Norcuron, Org NC 45;Piperidinium, 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide (1:1) CAS编号 50700-72-6 分子式 C34H57N2O4.Br 分子量 637.73 PubChem CID 39764 MDL号 MFCD00867762 Beilstein 4837308 EC号 256-723-9 Reaxys-RN 4106207 Merck Index 9941 规格或纯度 ≥99% 应用 A nonpolarizing neuromuscular relaxant 备注 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 生化机理 Vecuronium (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Althoμgh vecuronium bromide is often thoμght of as a muscle relaxant, it may be more accurate to classify it as a paralyzing agent.Competitive nicotinic acetylcholine receptor (nAChR) antagonist (IC 50 = 9.9 nM). Muscle relaxant. Inhibits neural response to hypoxia. 熔点 235 °C(dec.) 比旋光度 32° (C=1,0.05mol/L HCl) 敏感性 对热敏感 溶解性 Soluble in water, DMSO (128 mg/ml at 25 °C), and ethanol (128 mg/ml at 25 °C). 储存温度 -20°C储存 运输条件 超低温冰袋运输 Pei Y et al.  et al (2019) Excitotoxicity and compensatory upregulation of GAD67 in fetal rat hippocampus caused by prenatal nicotine exposure are associated with inhibition of the BDNF pathway. Food Chem Toxicol(Berl) 314-325 PMID：30389584 Fan G et al.  et al (2019) Decreased levels of H3K9ac and H3K27ac in the promotor region of ovarian P450 aromatase mediated low estradiol synthesis in female offspring rats induced by prenatal nicotine exposure as well as in human granulosa cells after nicotine treatment. Food Chem Toxicol(Berl) 256-266 PMID：30959089 Zhou J et al.  et al (2018) nAChRs-ERK1/2-Egr-1 signaling participates in the developmental toxicity of nicotine by epigenetically down-regulating placental 11ß-HSD2. Toxicol Appl Pharmacol(Berl) PMID：29486207 Zhang G et al.  et al (2018) Placental mechanism of prenatal nicotine exposure-reduced blood cholesterol levels in female fetal rats. Toxicol Lett(Berl) 31-38 PMID：30036686 Adenosine 下载 Adenosine 下载 Adenosine 下载 G PROTEIN-COUPLED RECEPTORS 下载 G PROTEIN-COUPLED RECEPTORS 下载 G PROTEIN-COUPLED RECEPTORS 下载 IP3 receptor 下载 IP3 receptor 下载 IP3 receptor 下载 Adrenoceptors, a1 下载 Adrenoceptors, a1 下载 Adrenoceptors, a1 下载 Adrenoceptors, a2 下载 Adrenoceptors, a2 下载 Adrenoceptors, a2 下载 Adrenoceptors, β 下载 Adrenoceptors, β 下载 Adrenoceptors, β 下载 GABAA (γ-aminobutyric acid) 下载 GABAA (γ-aminobutyric acid) 下载 GABAA (γ-aminobutyric acid) 下载 GABAB 下载 GABAB 下载 GABAB 下载 Calcium (voltage-gated) 下载 Calcium (voltage-gated) 下载 Calcium (voltage-gated) 下载 Phosphodiesterases 下载 Phosphodiesterases 下载 Phosphodiesterases 下载 Phosphoinositide Kinases 下载 Phosphoinositide Kinases 下载 Phosphoinositide Kinases 下载 Phospholipase A2 下载 Phospholipase A2 下载 Phospholipase A2 下载 Phospholipase C 下载 Phospholipase C 下载 Phospholipase C 下载 Phospholipase D 下载 Phospholipase D 下载 Phospholipase D 下载 Phosphoprotein Phosphatases 下载 Phosphoprotein Phosphatases 下载 Phosphoprotein Phosphatases 下载 Platelet-Activating Factor Receptors 下载 Platelet-Activating Factor Receptors 下载 Platelet-Activating Factor Receptors 下载 Protein Prenyltransferases 下载 Protein Prenyltransferases 下载 Protein Prenyltransferases 下载 Steroids Receptors 下载 Steroids Receptors 下载 Steroids Receptors 下载 Protein tyrosine phosphatases 下载 Protein tyrosine phosphatases 下载 Protein tyrosine phosphatases 下载 G Proteins (Heterotrimeric) 下载 G Proteins (Heterotrimeric) 下载 G Proteins (Heterotrimeric) 下载 Caspases 下载 Caspases 下载 Caspases 下载 Nitric Oxide Synthases 下载 Nitric Oxide Synthases 下载 Nitric Oxide Synthases 下载 Nonsteroidal Receptors 下载 Nonsteroidal Receptors 下载 Nonsteroidal Receptors 下载 Peroxisome proliferator activated receptors 下载 Peroxisome proliferator activated receptors 下载 Peroxisome proliferator activated receptors 下载 Ryanodine Receptors 下载 Ryanodine Receptors 下载 Ryanodine Receptors 下载 Adenylyl Cyclase 下载 Adenylyl Cyclase 下载 Adenylyl Cyclase 下载 GTP Binding Proteins 下载 GTP Binding Proteins 下载 GTP Binding Proteins 下载