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CAS:1246812-58-7|(Rac-Efavirenz-d4,依法韦仑-d4

CAS:1246812-58-7|(Rac-Efavirenz-d4,依法韦仑-d4

作者:德尔塔生物 日期:2025-10-22

生物活性:(Rac)-Efavirenz-d4 is a labelled racemic Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture[1]. (Rac)-Efavirenz-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Efavirenz-d4 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:319.70Formula:C14H5D4ClF3NO2CAS 号:1246812-58-7非标记 CAS:154598-52-4中文名称:依法韦仑-d4;施多宁-d4;依法韦伦-d4;依法维仑-d4;依氟维纶-d4;依非韦伦-d4;艾法韦仑-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Br

CAS:936230-75-0|β-Tocopherol-d3,β-生育酚-d3

CAS:936230-75-0|β-Tocopherol-d3,β-生育酚-d3

作者:德尔塔生物 日期:2025-10-22

生物活性:β-Tocopherol-d3 is the deuterium labeled β-Tocopherol. β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol can also prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.β-Tocopherol-d3 相关抗体:MiTF AntibodyZAP70 Antibody (YP4051)CD3 epsilon AntibodyCD3D AntibodyTRP1 Antibody (YA2327)Tyrosinase Antibody (YA2522)CD3G AntibodyZAP70 Antibody (YA651)FES Antibody (YA2820)分子量:419.70Formula:C28H45D3O2CAS 号:936230-75-0非标记 CAS:16698-35-4中文名称:β-生育酚-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Azzi A, et, al. d-alpha-tocopherol control of cell proliferation. Mol Aspects Med. 1993; 14(3): 265-71. [Content Brief][3]. Tasinato A, et, al. d-alpha-tocopherol inhibi

CAS:1795021-05-4|Sulthiame-d4,舒噻嗪 d4

CAS:1795021-05-4|Sulthiame-d4,舒噻嗪 d4

作者:德尔塔生物 日期:2025-10-22

生物活性:Sulthiame-d4 is the deuterium labeled Sultiame. Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic agent[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:294.38Formula:C10H10D4N2O4S2CAS 号:1795021-05-4非标记 CAS:61-56-3中文名称:舒噻嗪 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Milburn-McNulty P, et al. Sulthiame add-on therapy for epilepsy. Cochrane Database Syst Rev. 2015 Oct 28;(10):CD009472. [Content Brief]

CAS:1246820-95-0|Ulifloxacin-d8,乌利沙星-d8; 尤利沙星-d8

CAS:1246820-95-0|Ulifloxacin-d8,乌利沙星-d8; 尤利沙星-d8

作者:德尔塔生物 日期:2025-10-22

生物活性:Ulifloxacin-d8 is the deuterium labeled Ulifloxacin[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:357.43Formula:C16H8D8FN3O3SCAS 号:1246820-95-0非标记 CAS:112984-60-8中文名称:乌利沙星-d8; 尤利沙星-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

CAS:1189648-08-5|Melitracen-d6 hydrochloride,盐酸美力他欣 d6 (盐酸盐

CAS:1189648-08-5|Melitracen-d6 hydrochloride,盐酸美力他欣 d6 (盐酸盐

作者:德尔塔生物 日期:2025-10-22

生物活性:Melitracen-d6 (hydrochloride) is the deuterium labeled Melitracen hydrochloride. Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Melitracen-d6 hydrochloride 相关抗体:MTNR1A Antibody分子量:333.93Formula:C21H20D6ClNCAS 号:1189648-08-5非标记 CAS:10563-70-9中文名称:盐酸美力他欣 d6 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Xiaoqian Zhou , et al. The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis. Gastroenterol Res Pract. 2019 Feb 28;2019:3480732. [Content Brief][3]. K Shimamoto, et al. Myriatic E

CAS:1189805-13-7|Molindone-d8,盐酸吗啉吲酮-d8; (±-Molindone-d8; SPN-810M-d8

CAS:1189805-13-7|Molindone-d8,盐酸吗啉吲酮-d8; (±-Molindone-d8; SPN-810M-d8

作者:德尔塔生物 日期:2025-10-22

生物活性:Molindone-d8 is the deuterium labeled Molindone. Molindone hydrochloride (EN-1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Molindone-d8 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量:284.42Formula:C16H16D8N2O2CAS 号:1189805-13-7非标记 CAS:7416-34-4性状:固体颜色:Off-white to light yellow中文名称:盐酸吗茚酮-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.2%参考文献[1]. Yu C, et al. In vitro pharmacological characterization of SPN-810M (molindone). J Exp Pharmacol. 2018;10:65-73. Published 2018 Nov 21. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

CAS:1051419-24-9|Nevirapine-d3,奈韦拉平 d3

CAS:1051419-24-9|Nevirapine-d3,奈韦拉平 d3

作者:德尔塔生物 日期:2025-10-22

生物活性:Nevirapine-d3 (BI-RG 587-d3) is the deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nevirapine-d3 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:269.32Formula:C15H11D3N4OCAS 号:1051419-24-9非标记 CAS:129618-40-2中文名称:奈韦拉平 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Erickson DA, et al. Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitornevirapine by human hepatic cytochromes P-450. Drug Metab Dispos. 1999 Dec;27(12):1488-95. [Content Brief][3]. Dong JJ, et al. In vitro evaluation of the therapeutic potential of nevirapine in treatment of

CAS:1185237-43-7|(E/Z-Capsaicin-d3,辣椒素 d3

CAS:1185237-43-7|(E/Z-Capsaicin-d3,辣椒素 d3

作者:德尔塔生物 日期:2025-10-22

生物活性:(E/Z)-Capsaicin-d3 is the deuterium labeled (E/Z)-Capsaicin[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(E/Z)-Capsaicin-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 AntibodyAIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 Antibody分子量:308.43Formula:C18H24D3NO3CAS 号:1185237-43-7非标记 CAS:7553-53-9中文名称:辣椒素 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (516 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Br

CAS:1246814-57-2|Pamapimod-d4

CAS:1246814-57-2|Pamapimod-d4

作者:德尔塔生物 日期:2025-10-22

生物活性:Pamapimod-d4 (Ro4402257-d4) is the deuterium labeled Pamapimod. Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pamapimod-d4 相关抗体:p38 AntibodyPhospho-p38 (Thr180/Tyr182) AntibodyASK1 Antibody (YA609)MAPK14 AntibodyATF2 Antibodyp38 Antibody (YA696)Phospho-ATF2 (Thr71) AntibodyPhospho-MSK1 (Ser360) Antibodyp38 MAPK AntibodyGADD45A Antibody (YA1076)RRAS Antibody (YA3212)MAPKAP Kinase 2 AntibodyPhospho-MSK1 (Ser376) AntibodyMAP2K6 Antibody (YA1088)p40 Antibody (YA1500)PCPTP1 Antibody (YA1549)Sprouty 2 Antibody (YA1604)Sprouty 4 Antibody (YA1780)MAPKAP Kinase 3 Antibody (YA3070)MAPK6 Antibody (YA3194)分子量:410.41Formula:C19H16D4F2N4O4CAS 号:1246814-57-2非标记 CAS:449811-01-2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 K

CAS:1217623-85-2|Raclopride-d5 hydrochloride,雷氯必利 d5 (盐酸盐

CAS:1217623-85-2|Raclopride-d5 hydrochloride,雷氯必利 d5 (盐酸盐

作者:德尔塔生物 日期:2025-10-22

生物活性:Raclopride-d5 (hydrochloride) is the deuterium labeled Raclopride. Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively[1][2].IC50 & Target:D3 Receptor体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Raclopride-d5 hydrochloride 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量:352.27Formula:C15H16D5Cl3N2O3CAS 号:1217623-85-2非标记 CAS:98527-32-3性状:固体颜色:White to off-white中文名称:雷氯必利 d5 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:349554-02-5|Enalapril-d5 maleate

「同位素标记抑制剂」CAS:349554-02-5|Enalapril-d5 maleate

作者:德尔塔生物 日期:2025-10-21

生物活性:Enalapril-d5 (maleate) is deuterium labeled Enalapril, which is an angiotensin converting enzyme (ACE) inhibitor.分子量:497.55Formula:C24H27D5N2O9CAS 号:349554-02-5非标记 CAS:76095-16-4性状:固体颜色:White to off-white中文名称:马来酸依那普利 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

「同位素标记抑制剂」CAS:1276197-58-0|Carbidopa-d3 monohydrate

「同位素标记抑制剂」CAS:1276197-58-0|Carbidopa-d3 monohydrate

作者:德尔塔生物 日期:2025-10-21

生物活性:Carbidopa-d3 (monohydrate) is the deuterium labeled Carbidopa monohydrate. Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa monohydrate inhibits pancreatic cancer cell and tumor growth[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Carbidopa-d3 monohydrate 相关抗体:Aryl Hydrocarbon Receptor Antibody (YA2162)分子量:247.26Formula:C10H13D3N2O5CAS 号:1276197-58-0非标记 CAS:38821-49-7性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: ≥98.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Safe S. Carbidopa: a selective Ah receptor modulator (SAhRM). Biochem J. 2017;474(22):3763-3765. Published 2017 Nov 6. [Content Brief][3]. Fermaglich J. Treatment of Parkinson's disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa. Med Ann D

「同位素标记抑制剂」CAS:1246833-99-7|Nizatidine-d3

「同位素标记抑制剂」CAS:1246833-99-7|Nizatidine-d3

作者:德尔塔生物 日期:2025-10-21

生物活性:Nizatidine-d3 is the deuterium labeled Nizatidine. Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nizatidine-d3 相关抗体:ADGRE1 (F4/80) Antibody (YA002)ADGRE1 (F4/80) Antibody (YA920)分子量:334.48Formula:C12H18D3N5O2S2CAS 号:1246833-99-7非标记 CAS:76963-41-2性状:固体颜色:White to off-white中文名称:尼扎替丁 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

「同位素标记抑制剂」CAS:1189654-03-2|Clofibrate-d4

「同位素标记抑制剂」CAS:1189654-03-2|Clofibrate-d4

作者:德尔塔生物 日期:2025-10-21

生物活性:Clofibrate-d4 is the deuterium labeled Clofibrate. Clofibrate is an agonist of PPAR, with EC50s of 50 μM, ∼500 μM for murine PPARα and PPARγ, and 55 μM, ∼500 μM for human PPARα and PPARγ, respectively.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Clofibrate-d4 相关抗体:PPAR alpha AntibodyPPAR gamma AntibodyPPAR gamma Antibody (YA122)PGC1 beta Antibody (YA1411)分子量:246.72Formula:C12H11D4ClO3CAS 号:1189654-03-2非标记 CAS:637-07-0中文名称:氯贝特 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Willson TM, et al. The PPARs: from orphan receptors to drug discovery. J Med Chem. 2000 Feb 24;43(4):527-50. [Content Brief][3]. Chen Y, et al. Clofibrate Attenuates ROS Production by Lipid Overload in Cultured Rat Hepatoma Cells. J Pharm Pharm Sci. 2017;20(0):239-251. [Content Brief][4]. Chen SH, et al. Prenatal PPARα activation by clofibrate increases subcutaneous

「同位素标记抑制剂」CAS:1346600-86-9|Methocarbamol-d3

「同位素标记抑制剂」CAS:1346600-86-9|Methocarbamol-d3

作者:德尔塔生物 日期:2025-10-21

生物活性:Methocarbamol-d3 is the deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Methocarbamol-d3 相关抗体:xCT Antibody (YA006)xCT Antibody (YA652)Alpha-ENaC AntibodyCRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)CRMP4 Antibody (YA2777)分子量:244.26Formula:C11H12D3NO5CAS 号:1346600-86-9非标记 CAS:532-03-6性状:固体颜色:White to off-white中文名称:美索巴莫 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 98.15%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Bruce, R.B., L.B. Turnbull, and J.H. Newman, Metabolism of methocarbamol in the rat, dog, and human. J Pharm Sci, 1971. 60(1): p. 104-6. [C