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「同位素标记抑制剂」CAS:352534-94-2|MES-d13
作者:德尔塔生物 日期:2025-09-19
生物活性:MES-d13 is the deuterium labeled MES. MES (2-Morpholinoethanesulphonic acid) is a kind of amphoteric ion buffer, the buffer capacity ranging pH 5.5-7.0. As a Good's buffer, MES is widely used in biochemistry and molecular biology experiments, such as cell culture, enzyme activity determination, electrophoresis and protein studies[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.MES-d13 相关抗体:Mouse IgG Isotype Control6X His-tag (C-terminal) Antibody (YA860)DYKDDDDK Tag (FLAG) AntibodyGFP AntibodyMyc-tag AntibodyHA tag Antibody (YA856)GST-Tag Antibody HRP ConjugatedV5-tag AntibodyCollagen I alpha 2 AntibodyRabbit IgG Isotype Control6X His Tag (C-terminal) AntibodyHis Tag Antibody (HRP) (YA877)HA Tag Antibody (HRP) (YA876)EYFP Tag Antibody (YA872)HSV Tag Antibody (YA878)MBP Tag Antibody (YA879)RFP Tag Antibody (YA882)S Tag Antibody (YA883)SRT Tag Antibody (YA884)Strep-Tag II Antibody (YA885)TAP Tag Antibody (YA887)Collagen II AntibodyCollagen III AntibodyCollagen X AntibodyCollagen IV AntibodyCollagen I AntibodyCollagen VI alpha 1/2/3 Antibody (YA2637)AmCyan Tag Antibody (YA864)DsbA Tag Antibody (YA868)E2 Tag Antibody (YA870)分子量:208.32Formula:C6D13NO4SCAS 号:352534-94-2非标记 CAS
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「同位素标记抑制剂」CAS:7325-17-9|Glycerol-d8
作者:德尔塔生物 日期:2025-09-19
生物活性:Glycerol-d8 is the deuterium labeled Glycerol[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:100.14Formula:C3D8O3CAS 号:7325-17-9性状:液体颜色:Colorless to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month
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「同位素标记抑制剂」CAS:148706-06-3|4-Hydroxynonenal-d3
作者:德尔塔生物 日期:2025-09-19
生物活性:4-Hydroxynonenal-d3 is the deuterium labeled 4-Hydroxynonenal. 4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modulate a number of signaling processes mainly through forming covalent adducts with nucleophilic functional groups in proteins, nucleic acids, and membrane lipids. 4-Hydroxynonenal plays an important role in cancer through mitochondria[1][2][3].IC50 & Target:ALDH2体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4-Hydroxynonenal-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)ALDH1A1 AntibodyAsparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibo
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「同位素标记抑制剂」CAS:1216678-68-0|Mirtazapine-d3
作者:德尔塔生物 日期:2025-09-19
生物活性:Mirtazapine-d3 is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors[1].IC50 & Target[1]:5-HT2 Receptor5-HT3 Receptor体内研究(In Vivo)米氮平 (腹膜内注射;10-50 mg/Kg;14 天) 处理可使心率、呼吸率、焦虑水平正常化并消除在 MeCP2 缺失小鼠中观察到的跳跃行为,从而改善表型评分[2]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Animal Model:MeCP2 null mice[2]Dosage:10-50 mg/KgAdministration:Intraperitoneal injection; 10-50 mg/Kg; 14 daysResult:Restored the thickness of MeCP2-null mice somatosensory cortex, especially of layers II-III and VI.分子量:268.38Formula:C17H16D3N3CAS 号:1216678-68-0非标记 CAS:85650-52-8性状:固体颜色:White to off-white中文名称:米氮平杂质13 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month
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「同位素标记抑制剂」CAS:721948-65-8|Abscisic acid-d6
作者:德尔塔生物 日期:2025-09-19
生物活性:Abscisic acid-d6 is deuterium labeled Abscisic acid. Abscisic acid inhibits proton pump (H+-ATPase)[1].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Abscisic acid-d6 相关抗体:PMCA1 Antibody (YA1676)分子量:270.36Formula:C15H14D6O4CAS 号:721948-65-8非标记 CAS:21293-29-8性状:固体颜色:White to off-white中文名称:(+)-脱落酸-d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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「同位素标记抑制剂」Quinolinic acid-13C7
作者:德尔塔生物 日期:2025-09-19
生物活性:Quinolinic acid-13C7 is the 13C labeled Quinolinic acid (HY-100807)[1]. Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction[2][3].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Quinolinic acid-13C7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyPSD95 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNMDAR1 AntibodyNMDAR2A AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin Antibody分子量:174.07Formula:13C7H5NO4CAS 号:1346642-91-8非标记 CAS:89-00-9中文名称:喹啉酸-13C7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (543 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the
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「同位素标记抑制剂」Trimethoprim-13C3
作者:德尔塔生物 日期:2025-09-19
生物活性:Trimethoprim-13C3 is the deuterium labeled Trimethoprim (HY-B0510)[1]. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc[2][3][4][5].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Trimethoprim-13C3 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Poliovirus Receptor Antibody (YA2556)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:293.30Formula:C1113C3H18N4O3CAS 号:1189970-95-3非标记 CAS:738-70-5中文名称:甲氧苄啶-13C3;甲氧苄氨嘧啶-13C3;甲氧苄嘧啶-13C3;甲氧苄胺嘧啶-13C3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions
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「同位素标记抑制剂」Deruxtecan-d6
作者:德尔塔生物 日期:2025-09-19
生物活性:Deruxtecan-d6 is the deuterium labeled Deruxtecan[1].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:1040.09Formula:C52H50D6FN9O13CAS 号:2760715-89-5非标记 CAS:1599440-13-7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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「同位素标记抑制剂」Acetaminophen glucuronide-d3
作者:德尔塔生物 日期:2025-09-19
生物活性:Acetaminophen glucuronide-d3 is the deuterium labeled Acetaminophen glucuronide[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:330.31Formula:C14H14D3NO8CAS 号:1260981-52-9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (517 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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「同位素标记抑制剂」Tedizolid-13C,d3
作者:德尔塔生物 日期:2025-09-19
生物活性:Tedizolid-13C,d3 is the 13C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[54].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tedizolid-13C,d3 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:374.35Formula:C1613CH12D3FN6O3CAS 号:2931763-72-1非标记 CAS:856866-72-3中文名称:特地唑胺-13C,d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokine
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「同位素标记抑制剂」Fmoc-L-Lys (Boc)-OH-13C6,15N2
作者:德尔塔生物 日期:2025-09-19
生物活性:Fmoc-L-Lys (Boc)-OH-13C6,15N2 is a 15N-labeled and 13C-labled Triclabendazole.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fmoc-L-Lys (Boc)-OH-13C6,15N2 相关抗体:alpha Tubulin AntibodyLC3A/B AntibodyBeta Tubulin Antibodybeta Tubulin Antibody (YA839)Doublecortin AntibodyLC3B Antibody (YA308)Stathmin 1 Antibody (YA049)Stathmin 1 Antibody (YA050)alpha Tubulin (acetyl K40) Antibodybeta III Tubulin Antibodygamma Tubulin AntibodyLC3B AntibodyBeta Tubulin Antibody (HRP) (YA865)Cytokeratin 5 AntibodyMAP2 AntibodyDM1 Antibody (YA898)CK18 AntibodyCytokeratin 19 AntibodyCytokeratin 7 Antibody (YA951)Cytokeratin 15 Antibody (YA1493)p63 Antibody (YA1531)Cytokeratin 6 Antibody (YA1701)Cytokeratin 4 Antibody (YA1762)Cytokeratin 10 Antibody (YA1857)Cytokeratin 14 Antibody (YA1876)Cytokeratin 1 Antibody (YA2665)Stanniocalcin 1 Antibody (YA2690)Cytokeratin 13 Antibody (YA2695)HRH3 Antibody (YA2701)Phospho-alpha Tubulin (Tyr272) Antibody (YA3041)分子量:476.48Formula:C2013C6H3215N2O6CAS 号:850080-89-6非标记 CAS:71989-26-9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet
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「同位素标记抑制剂」Etoperidone-d8 hydrochloride
作者:德尔塔生物 日期:2025-09-19
生物活性:Etoperidone-d8 (hydrochloride) is the deuterium labeled Etoperidone hydrochloride[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:422.42Formula:C19H21D8Cl2N5OCAS 号:1329796-60-2非标记 CAS:57775-22-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Flunixin-d3
作者:德尔塔生物 日期:2025-09-19
生物活性:Flunixin-d3 is the deuterium labeled Flunixin. Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Flunixin-d3 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量:299.26Formula:C14H8D3F3N2O2CAS 号:1015856-60-6非标记 CAS:38677-85-9中文名称:氟尼克辛-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Cox L, et al. Levomepromazine for nausea and vomiting in palliative care. Cochrane Database Syst Rev. 2015;2015(11):CD009420. Published 2015 Nov 2. [Content Brief][2]. Cheng Z, et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation. 1998 Aug;22(4):353-66. [Content Brief][3]. Bryant, C.E., B.A. Farnfield, and H.J. Janicke, Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nu
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「同位素标记抑制剂」1'-Hydroxymidazolam-13C3
作者:德尔塔生物 日期:2025-09-19
生物活性:1'-Hydroxymidazolam-13C3 is the 13C labeled 1'-Hydroxymidazolam[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.1'-Hydroxymidazolam-13C3 相关抗体:FMO3 Antibody (YA1992)分子量:344.74Formula:C1513C3H13ClFN3OCAS 号:1189677-14-2非标记 CAS:59468-90-5中文名称:咪达唑仑杂质1-13C3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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「同位素标记抑制剂」Tianeptine-d12
作者:德尔塔生物 日期:2025-09-19
生物活性:Tianeptine-d12 is a deuterated analog of Tianeptine. Tianeptine is an antidepressant with oral activity and neurochemical properties. Tianeptine has neuroprotective effects against hypoxia in tissue culture and against the deleterious effects of cytokines in the cortex and white matter, but not against NMDA receptor-mediated excitotoxicity[1][2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:449.03Formula:C21H13D12ClN2O4SCAS 号:1189870-26-5非标记 CAS:72797-41-2中文名称:噻奈普汀 d12运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Wagstaff A J, et al. Tianeptine: a review of its use in depressive disorders[J]. CNS drugs, 2001, 15: 231-259.[3]. Plaisant F, et al. Neuroprotective properties of tianeptine: interactions with cytokines[J]. Neuropharmacology, 2003, 44(6): 801-809. [Content Brief][4]. Sharma A K, et al. Effects of calcium channel blocker,