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Cy5-PEG3-azide
作者:德尔塔 日期:2022-09-29
Cy5-PEG3-azide是一种PROTAClinker,属于PEG类。可用于合成PROTAC分子。Cy5-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 别名 N/A 化学名 N/A Canonical SMILES CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)C(C=CC=C4)=C4C3(C)C.[Cl-] 分子式 C40H55ClN6O4 分子量 719.36 溶解度 N/A 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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CY5-N3
作者:德尔塔 日期:2022-09-29
CY5-N3是一种Cy5-叠氮化物,是一种荧光染料。CY5-N3 is a Cy5-azide, which is a fluorescent dye.Cas No. 1621101-43-6 SDF 别名 N/A 化学名 N/A Canonical SMILES CC1(C)/C(N(C2=CC=C(S(=O)(O)=O)C=C21)CCCCCC(NCCCN=[N+]=[N-])=O)=C\C=C\C=C\C(C(C)(C3=CC(S(=O)([O-])=O)=CC=C43)C)=[N+]4CC 分子式 C36H46N6O7S2 分子量 738.92 溶解度 DMSO : 25 mg/mL (33.83 mM) 储存条件 Store at -20°C,unstable in solution, ready to use. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5 NHS ester(Et)
作者:德尔塔 日期:2022-09-29
氨基反应性荧光染料,溶于水 别名 N/A 化学名 N/A Canonical SMILES CC1(C)C2=C(C=CC(S(=O)([O-])=[O-])=C2)[N+](CCCCCC(ON3C(CCC3=O)=O)=O)=C1/C=C/C=C/C=C4N(CC)C5=CC=C(S(=O)([O-])=O)C=C5C/4(C)C.[Na+] 分子式 C37H42N3NaO10S2 分子量 775.86 溶解度 insoluble in EtOH; >1.5 mg/mL in H2O with ultrasonic; >16.67 mg/mL in DMSO 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5 NHS ester (non-sulfonated)
作者:德尔塔 日期:2022-09-29
Labeling of amino-groups in biomolecules.Cyanine5 NHS ester is a ideal reactive dye for the labeling of peptides, proteins, and oligonucleotides which contain the amino-groups. Recently, among the life science research and diagnostics, Dye color quantity can be detected in gel electrophoresis by naked eye as the dye color is very intense and as small as 1 nanomol. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. For more sophisticated targets such as easily degradable proteins, when use of DMF or DMSO is undesirable, consider using water-soluble Cy5 NHS ester which does not require co-solvent, and has very similar fluorescent properties. 别名 N/A 化学名 (2,5-dioxopyrrolidin-1-yl) 6-[(2E)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]hexanoate Canonical SMILES CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCCCCC(=O)ON5C(=O)CCC5=O)(C)C)C)C 分子式 C36H42ClN3O4 分子量 616.19 溶解度 ≥ 30.8mg/mL in DMSO, ≥ 15.1 mg/mL in EtOH with ultrasonic 储存条件 Store at -20°C, protect from light General tips For obtaining a higher solubilit
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Cy5 NHS ester
作者:德尔塔 日期:2022-09-29
Cy5 NHS ester(Cyanine5 NHS ester) is a Red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides.
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Cy5 maleimide (non-sulfonated)
作者:德尔塔 日期:2022-09-29
Labeling of cysteine residues, as well as other thiolated moleculesCy5 maleimide is a mono-reactive dye for selectively labeling peptides and proteins which couples with thiol groups. The labeling reagent is a common fluorophore dye with low aqueous solubility which is compatible with various instrumentation like microscopes, imagers, and fluorescence readers. Cy5 maleimide is part of the probe among the biological research. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. The user can generate probes with virtually any non-genetically encoded moiety of interest with the scaffold in hand.Cas No. SDF 化学名 6-[(2E)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]hexanamide Canonical SMILES CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCCCCC(=O)NCCN5C(=O)C=CC5=O)(C)C)C)C 分子式 C38H45ClN4O3 分子量 641.24 溶解度 ≥ 64.1mg/mL in DMSO, ≥ 65 mg/mL in EtOH 储存条件 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
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Cy5 hydrazide (non-sulfonated)
作者:德尔塔 日期:2022-09-29
carbonyl-reactive dyeCy5 hydrazide is a reactive dye which reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. The labeling regent is used for the labeling of aldehydes and ketones. The dye examples are proteins subjected to oxidative stress, glycoproteins pre-activated by periodate oxidation, and oligonucleotides with aldehyde moieties. Cy5 hydrazide could replace carbonyl-reactive Alexa Fluor 647 and DyLight 649 dyes. For biomolecule labeling, the labeling regent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. 别名 N/A 化学名 N/A Canonical SMILES CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(N[NH3+])=O)C4=CC=CC=C4C3(C)C 分子式 C32H42Cl2N4O 分子量 569.61 溶解度 ≥ 48mg/mL in DMSO 储存条件 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice
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Cy5 carboxylic acid(Et)
作者:德尔塔 日期:2022-09-29
非反应性荧光团,用于对照实验和校准 ,溶于水 别名 N/A 化学名 N/A Canonical SMILES CC1(C)C2=C(C=CC(S(=O)([O-])=O)=C2)[N+](CCCCCC(O)=O)=C1/C=C/C=C/C=C3N(CC)C4=CC=C(S(=O)([O-])=O)C=C4C/3(C)C.[Na+] 分子式 C33H39N2NaO8S2 分子量 678.79 溶解度 >67.9 mg/mL in H2O; >6.83 mg/mL in EtOH; >8.56 mg/mL in DMSO 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5 carboxylic acid (non-sulfonated)
作者:德尔塔 日期:2022-09-29
Non-reactive fluorophore, for control experiments, and for calibrationCy5 carboxylic acid is a non-activated carboxylic acid with low aqueous solubility. For coupling with amines, or protein labeling, Cy5 NHS ester and water-soluble sulfo-Cy5 NHS ester is preferred. This labeling dye has limited water solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. 别名 N/A 化学名 6-[(2E)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]hexanoic acid Canonical SMILES CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCCCCC(=O)O)(C)C)C)C 分子式 C32H39ClN2O2 分子量 519.12 溶解度 ≥ 51.9mg/mL in DMSO, ≥ 89 mg/mL in EtOH 储存条件 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All othe
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Cy5 carboxylic acid
作者:德尔塔 日期:2022-09-29
Non-reactive fluorophore, for control experiments, and for calibrationSulfo-Cy5 carboxylic acid is a non-activated, sulfonated, hydrophilic and highly water soluble dye. Non-Sulfo-Cy5 carboxylic acid analog is available. For kinds of researches related experiments, using pre-activated sulfo-Cy5 NHS ester is preferred. To labeling proteins and peptides, no organic co-solvent is needed. In life science, the sulfonate groups make the Cy dyes soluble in water and also reduce fluorescence-quenching which can arise from dye–dye interactions.Cas No. SDF 化学名 (2E)-1-(5-carboxypentyl)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethyl-5-sulfonatoindol-1-ium-2-yl)penta-2,4-dienylidene]indole-5-sulfonate Canonical SMILES CC1(C2=C(C=CC(=C2)S(=O)(=O)[O-])[N+](=C1C=CC=CC=C3C(C4=C(N3CCCCCC(=O)O)C=CC(=C4)S(=O)(=O)[O-])(C)C)C)C 分子式 分子量 溶解度 储存条件 General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5 Boc-hydrazide (non-sulfonated)
作者:德尔塔 日期:2022-09-29
carbonyl-reactive dye 别名 N/A 化学名 1-(6-(2-(tert-butoxycarbonyl)hydrazinyl)-6-oxohexyl)-3,3-dimethyl-2-((1E,3E,5E)-5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium Canonical SMILES CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NNC(OC(C)(C)C)=O)=O)C4=CC=CC=C4C3(C)C 分子式 C37H49ClN4O3 分子量 633.26 溶解度 good in dichloromethane, polar organic solvents (DMF, DMSO), alcohols, low in water 储存条件 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5 Bis NHS ester
作者:德尔塔 日期:2022-09-29
荧光染料,含有两个氨基反应基团,溶于水 别名 N/A 化学名 N/A Canonical SMILES CC1(C)C2=C(C=CC(S(=O)([O-])=[O-])=C2)[N+](CCCCCC(ON3C(CCC3=O)=O)=O)=C1/C=C/C=C/C=C4N(CCCCCC(ON5C(CCC5=O)=O)=O)C6=CC=C(S(=O)([O-])=O)C=C6C/4(C)C.[Na+] 分子式 C45H51N4NaO14S2 分子量 959.02 溶解度 Soluble in DMSO 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5 Bis carboxylic acid
作者:德尔塔 日期:2022-09-29
非反应性荧光团,用于对照实验和校准,溶于水 别名 N/A 化学名 N/A Canonical SMILES CC1(C)C2=C(C=CC(S(=O)([O-])=O)=C2)[N+](CCCCCC(O)=O)=C1/C=C/C=C/C=C3N(CCCCCC(O)=O)C4=CC=C(S(=O)([O-])=O)C=C4C/3(C)C.[Na+] 分子式 C37H45N2NaO10S2 分子量 764.88 溶解度 Soluble in DMSO 储存条件 Store at -20°C General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
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Cy5 azide (non-sulfonated)
作者:德尔塔 日期:2022-09-29
used for Click chemistry to label alkyne-modified oligonucleotidesCy5 azide is a labeling reagent ready for the use in Click Chemistry reaction which available as 10 mM solution in DMSO. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. Alkyne-modified biomolecules in mixtures of water with organic solvents can be labeled by Cy5 azide.Cas No. SDF 化学名 N-(3-azidopropyl)-6-[(2E)-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethylindol-1-ium-2-yl)penta-2,4-dienylidene]indol-1-yl]hexanamide Canonical SMILES CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=C3C(C4=CC=CC=C4N3CCCCCC(=O)NCCCN=[N+]=[N-])(C)C)C)C 分子式 C35H45ClN6O 分子量 601.22 溶解度 ≥ 60.1mg/mL in DMSO, ≥ 49.1 mg/mL in EtOH with ultrasonic 储存条件 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with
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Cy5 azide
作者:德尔塔 日期:2022-09-29
used for Click chemistry to label alkyne-modified oligonucleotidesSulfo-Cy5 azide is a sulfonated, hydrophilic and highly water soluble dye for Click chemistry. Due to this features, the dye can be used for labeling biomolecules, especially useful for the labeling of delicate proteins and proteins prone to denaturation, purely aqueous conditions. Sulfo-Cy5 azide is not only a sulfonated but also a popular fluorophore. For labeling proteins and peptides, no organic co-solvent is needed. In life science, the sulfonate groups make the Cy dyes soluble in water and also reduce fluorescence-quenching which can arise from dye–dye interactions. 别名 N/A 化学名 (2E)-1-[6-(3-azidopropylamino)-6-oxohexyl]-3,3-dimethyl-2-[(2E,4E)-5-(1,3,3-trimethyl-5-sulfonatoindol-1-ium-2-yl)penta-2,4-dienylidene]indole-5-sulfonate Canonical SMILES CC1(C2=C(C=CC(=C2)S(=O)(=O)[O-])[N+](=C1C=CC=CC=C3C(C4=C(N3CCCCCC(=O)NCCCN=[N+]=[N-])C=CC(=C4)S(=O)(=O)[O-])(C)C)C)C 分子式 C36H47N6NaO8S2 分子量 778.91 溶解度 very high in water 储存条件 Store at -20°C in the dark General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. Shipping Condition Evaluation sample solution : ship with blue ice All other available size: sh