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CAS:1217731-56-0|rel-Abacavir-d4，阿巴卡韦-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：rel-Abacavir-d4 is the deuterium labeled rel-Abacavir[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：290.36Formula：C14H14D4N6OCAS 号：1217731-56-0非标记 CAS：136470-78-5中文名称：阿巴卡韦-d4；阿巴卡维-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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CAS:1178903-96-2|Cyclophosphamide-d8，环磷酰胺-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Cyclophosphamide-d8 is deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cyclophosphamide-d8 相关抗体:FANCA Antibody (YA2112)FANCD2 Antibody (YA3102)FANCB Antibody (YA2804)分子量：269.14Formula：C7H7D8Cl2N2O2PCAS 号：1178903-96-2非标记 CAS：50-18-0中文名称：环磷酰胺-d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (532 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Schwartz PS, et al. Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells. Mol Pharmacol. 2001 Dec;60(6):1268-1279. [Content Brief][3]. al-Jafari AA, et al. Inhibition of human acetylcholinesterase by cyclophosphamide. Toxicology. 1995 Jan 19;96(1):1-6. [Content Brief][4]. Harris RN, et al. Carbon tetrachloride-induced increase in the antitumor activity of cycl
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CAS:1261079-38-2|Naloxone-d5，纳洛酮-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Naloxone D5 is deuterium labeled Naloxone. Naloxone is a a potent opioid receptor antagonist.分子量：332.41Formula：C19H16D5NO4CAS 号：1261079-38-2非标记 CAS：465-65-6中文名称：纳洛酮-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (502 KB)产品使用指南 (1538 KB)
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CAS:1285910-03-3|Nisoldipine-d6，BAY-k 5552-d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Nisoldipine-d6 is the deuterium labeled Nisoldipine. Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with an IC50 of 10 nM.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nisoldipine-d6 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCatalase Antibody (YA552)Catalase Antibody (YA811)Cardiac Troponin I/TNNC1 AntibodyC Reactive Protein Antibody (YA941)SCGN Antibody (YA1167)PARK7/DJ1 Antibody (YA1799)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)C Reactive Protein Antibody (YA939)C Reactive Protein Antibody (YA940)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)PON1 Antibody (YA1666)PON2 Antibody (YA1688)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)分子量：394.45Formula：C20H18D6N2O6CAS 号：1285910-03-3非标记 CAS：63675-72-9中文名称：尼索地平 d6运输条件：Room temperature i
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CAS:1189455-63-7|Loxapine-d8，洛沙平-d8；克噻平-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Loxapine-d8 is the deuterium labeled Loxapine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Loxapine-d8 相关抗体:DRD2 AntibodyMTNR1A AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：335.86Formula：C18H10D8ClN3OCAS 号：1189455-63-7非标记 CAS：54810-23-0中文名称：洛沙平-d8；克噻平-d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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CAS:1132641-22-5|Rosiglitazone-d3，罗格列酮 d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Rosiglitazone-d3 is the deuterium labeled Rosiglitazone. Rosiglitazone (BRL 49653) is a selective, orally active PPARγ agonist with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively. Rosiglitazone binds to PPARγ with a Kd of approximately 40 nM. Rosiglitazone is also an activator of TRPC5 (EC50=~30 μM) and an inhibitor of TRPM3[1][2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Rosiglitazone-d3 相关抗体:Ferritin Heavy Chain AntibodyPPAR alpha AntibodyPPAR gamma AntibodyPPAR gamma Antibody (YA122)AMID/FSP1 AntibodyPeroxiredoxin 1 Antibody (YA692)PRDX3 Antibody (YA909)TRPM8 Antibody (YA1609)TRPM7 Antibody (YA2391)Ferritin Light Chain Antibody (YA971)Ferritin Light Chain Antibody (YA972)PGC1 beta Antibody (YA1411)TrpC1 Antibody (YA1814)分子量：360.45Formula：C18H16D3N3O3SCAS 号：1132641-22-5非标记 CAS：122320-73-4中文名称：罗格列酮 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pha
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CAS:544684-93-7|Rofecoxib-d5，罗非考昔 d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Rofecoxib-d5 is the deuterium labeled Rofecoxib. Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells)[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Rofecoxib-d5 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量：319.39Formula：C17H9D5O4SCAS 号：544684-93-7非标记 CAS：162011-90-7中文名称：罗非考昔 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (537 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Rofecoxib, et al. Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Phar
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CAS:1332075-40-7|Tirofiban-d9，替罗非班-d9; L700462-d9; MK383-d9
作者：德尔塔生物 日期：2025-07-08
生物活性：Tirofiban-d9 is deuterium labeled Tirofiban.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tirofiban-d9 相关抗体:Fibronectin Antibody (YA762)Pan-Cadherin AntibodyPaxillin AntibodyIntegrin alpha 5 AntibodyIntegrin alpha V AntibodyIntegrin beta 1 AntibodyIntegrin beta 3 AntibodyFibronectin AntibodyICAM1 Antibody (YA725)ICAM1 Antibody (YA352)VCAM1 AntibodyCD41 Antibody (YA1839)Fibrinogen gamma Chain Antibody (YA1896)Fibrinogen alpha Chain Antibody (YA2069)ELMO1 Antibody (YA2243)von Willebrand Factor Antibody (YA2406)Integrin alpha 6 Antibody (YA3020)Integrin alpha 2 Antibody (YA3107)Integrin beta 5 Antibody (YA3108)Integrin beta 6 Antibody (YA3122)Integrin beta 4 Antibody (YA3280)Integrin alpha 9 Antibody (YA1660)alpha Internexin Antibody (YA2067)Integrin alpha L Antibody (YA2398)Vitronectin Antibody (YA2402)MADCAM1 Antibody (YA2744)ICAM2 Antibody (YA3007)ICAM3 Antibody (YA3009)Integrin alpha E Antibody (YA3051)Integrin Linked ILK Antibody (YA3111)分子量：449.65Formula：C22H27D9N2O5SCAS 号：1332075-40-7非标记 CAS：144494-65-5中文名称：替罗非班-d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of
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CAS:1092540-50-5|Atazanavir-d6，阿扎那韦-d6; BMS-232632-d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Atazanavir-d6 is deuterium labeled Atazanavir. Atazanavir (BMS-232632), a highly selective HIV-1 protease inhibitor, is the first protease inhibitor approved for once-daily administration[1]. Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp)[2]. Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM[3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Atazanavir-d6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCytochrome C AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CD4 AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyCytochrome P450 17A1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Aromatase AntibodyAsparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)分子量：710.89Formula：C38H46D6N6O7CAS 号：1092540-50-5非标记 CAS：198904-31-3性状：固体颜色：White to off-white中文名称：阿扎那韦-d6运输条件：Ro
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CAS:1092540-52-7|Atazanavir-d18，阿扎那韦-d18; BMS-232632-d18
作者：德尔塔生物 日期：2025-07-08
生物活性：Atazanavir-d18 is the d18 labled Atazanavir (HY-17367). Atazanavir is a selective HIV-1 protease inhibitor[1].IC50 & Target：HIV-1体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Atazanavir-d18 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量：722.97Formula：C38H34D18N6O7CAS 号：1092540-52-7非标记 CAS：198904-31-3中文名称：阿扎那韦-d18运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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CAS:1356840-08-8|Moexiprilat-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Moexiprilat-d5 is deuterium labeled Moexiprilat.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：475.55Formula：C25H25D5N2O7CAS 号：1356840-08-8非标记 CAS：103775-14-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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CAS:1185242-27-6|Cinnarizine-d8，桂利嗪 d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Cinnarizine-d8 is a deuterium labeled Cinnarizine. Cinnarizine is an antihistamine and a calcium channel blocker.分子量：376.56Formula：C26H20D8N2CAS 号：1185242-27-6非标记 CAS：298-57-7性状：固体颜色：Light yellow to yellow中文名称：桂利嗪 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1185878-98-1|Pentoxifylline-d6，BL-191-d6; PTX-d6; Oxpentifylline-d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Pentoxifylline-d6 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pentoxifylline-d6 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)PDE4D Antibody (YA1714)Tat SF1 Antibody (YA2886)分子量：284.34Formula：C13H12D6N4O3CAS 号：1185878-98-1非标记 CAS：6493-05-6性状：固体颜色：White to off-white中文名称：己酮可可碱 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:2122830-90-2|Flibanserin-d4，BIMT-17-d4; BIMT-17BS-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Flibanserin-d4 is a deuterium labeled Flibanserin (BIMT-17). Flibanserin is a full agonist of the serotonin 5-HT1A receptor (Ki=1 nM) and an antagonist of 5-HT2A (49 nM)[1].分子量：394.43Formula：C20H17D4F3N4OCAS 号：2122830-90-2非标记 CAS：167933-07-5中文名称：氟立班丝氨 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Invernizzi RW, et al. Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors. Br J Pharmacol. 2003 Aug;139(7):1281-8. [Content Brief]
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CAS:1246815-00-8|Fenvalerate-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Fenvalerate-d5 is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fenvalerate-d5 相关抗体:PFKFB3 AntibodyDUSP1 AntibodyDUSP3 AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Intestinal Alkaline Phosphatase Antibody (YA1559)PFKL Antibody (YA1597)SHP2 Antibody (YA1643)PP1C alpha/beta Antibody (YA1700)PTP1B Antibody (YA1776)PLEKHA1 Antibody (YA2145)PGAM1 Antibody (YA2156)DUSP6 Antibody (YA2280)PRAS40 Antibody (YA3179)PPP4C Antibody (YA687)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Phospho-PTP1B (Ser352) Antibody (YA1027)Phospho-PTP1B (Ser378) Antibody (YA1028)Placental Alkaline Phosphatase Antibody (YA1038)Placental Alkaline Phosphatase Antibody (YA1039)PP1C alpha Antibody (YA1040)PP1C alpha Antibody (YA1041)SHP1 Antibody (YA1044)SHP1 Antibody (YA1045)Anthrax Protective gen Antibody (YA1060)PP1C gamma Antibody (YA1068)PPP5C Antibody (YA1069)分子量：424.93Formula：C25H17D5ClNO3CAS 号：1246815-00-8非标记 CA
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