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「同位素标记抑制剂」CAS:2098655-72-0|3-Chlorobenzoic acid-d4

「同位素标记抑制剂」CAS:2098655-72-0|3-Chlorobenzoic acid-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:3-Chlorobenzoic acid-d4 is the deuterium labeled 3-Chlorobenzoic acid-d4[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:160.59Formula:C7HD4ClO2CAS 号:2098655-72-0运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

「同位素标记抑制剂」CAS:85577-25-9|4-Chlorobenzoic acid-d4

「同位素标记抑制剂」CAS:85577-25-9|4-Chlorobenzoic acid-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:4-Chlorobenzoic acid-d4 is the deuterium labeled 4-Chlorobenzoic acid-d4[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:160.59Formula:C7HD4ClO2CAS 号:85577-25-9中文名称:对氯苯甲酸-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

「同位素标记抑制剂」CAS:25837-47-2|1-(Ethynyl-d)benzene-2,3,4,5,6-d5

「同位素标记抑制剂」CAS:25837-47-2|1-(Ethynyl-d)benzene-2,3,4,5,6-d5

作者:德尔塔生物 日期:2025-06-13

生物活性:1-(Ethynyl-d)benzene-2,3,4,5,6-d5 is the deuterium labeled 1-(Ethynyl-d)benzene[1]. 1-(Ethynyl-d)benzene-2,3,4,5,6-d5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:108.17Formula:C₈D₆CAS 号:25837-47-2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

「同位素标记抑制剂」CAS:70837-27-3|2-(Methyl-d3)phenol

「同位素标记抑制剂」CAS:70837-27-3|2-(Methyl-d3)phenol

作者:德尔塔生物 日期:2025-06-13

生物活性:2-(Methyl-d3)phenol is the deuterium labeled 2-(Methyl)phenol[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:111.16Formula:C₇H₅D₃OCAS 号:70837-27-3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

「同位素标记抑制剂」CAS:1515861-68-3|N,N-dimethyl-N-((phenyl-dd5)methyl)tetradecan-1-aminium bromide

「同位素标记抑制剂」CAS:1515861-68-3|N,N-dimethyl-N-((phenyl-dd5)methyl)tetradecan-1-aminium bromide

作者:德尔塔生物 日期:2025-06-13

生物活性:N,N-dimethyl-N-((phenyl-dd5)methyl)tetradecan-1-aminium bromide is the deuterium labeled N,N-dimethyl-N-((phenyl-d5)methyl)tetradecan-1-aminium bromide[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:417.52Formula:C23H37D5BrNCAS 号:1515861-68-3非标记 CAS:18773-88-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (516 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

「同位素标记抑制剂」CAS:2470243-19-5|Demethoxycurcumin-d7

「同位素标记抑制剂」CAS:2470243-19-5|Demethoxycurcumin-d7

作者:德尔塔生物 日期:2025-06-13

生物活性:Demethoxycurcumin-d7 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Demethoxycurcumin-d7 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量:345.40Formula:C20H11D7O5CAS 号:2470243-19-5非标记 CAS:22608-11-3中文名称:去甲氧基姜黄素 d7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使

「同位素标记抑制剂」CAS:1217780-28-3|(±)-Epicatechin-13C3

「同位素标记抑制剂」CAS:1217780-28-3|(±)-Epicatechin-13C3

作者:德尔塔生物 日期:2025-06-13

生物活性:(±)-Epicatechin-13C3 is the 13C labeled (±)-Epicatechin. (-)-Epicatechin (HY-N0001) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(±)-Epicatechin-13C3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)COX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyAMID/FSP1 Antibody分子量:293.25Formula:C1213C3H14O6CAS 号:1217780-28-3非标记 CAS:490-46-0中文名称:表儿茶素-13C3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate

「同位素标记抑制剂」CAS:95046-87-0|1-Acetylnaphthalene-d3

「同位素标记抑制剂」CAS:95046-87-0|1-Acetylnaphthalene-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:1-Acetylnaphthalene-d3 is the deuterium labeled 1-Acetylnaphthalene[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:173.23Formula:C12H7D3OCAS 号:95046-87-0非标记 CAS:941-98-0运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

「同位素标记抑制剂」CAS:2140317-01-5|Regorafénib N-oxyde (M2)-13C,d3

「同位素标记抑制剂」CAS:2140317-01-5|Regorafénib N-oxyde (M2)-13C,d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Regorafénib N-oxyde (M2)-13C,d3 is the 13C- and deuterium labeled Regorafénib N-oxyde (M2). Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[90].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Regorafénib N-oxyde (M2)-13C,d3 相关抗体:FMO3 Antibody (YA1992)分子量:502.83Formula:C2013CH12D3ClF4N4O4CAS 号:2140317-01-5非标记 CAS:835621-11-9中文名称:瑞戈非尼氮氧化物(M2代谢物)-13C,d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief][2]. Allard M, et al. Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC-MS/MS. J Pharm Biomed Anal. 2017 Aug 5;142:42-48. [Content Brief]

「同位素标记抑制剂」CAS:1333489-03-4|Regorafénib N-oxyde-d3(M2)

「同位素标记抑制剂」CAS:1333489-03-4|Regorafénib N-oxyde-d3(M2)

作者:德尔塔生物 日期:2025-06-13

生物活性:Regorafénib N-oxyde-d3(M2) is the deuterium labeled Regorafénib N-oxyde M2[1]. Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Regorafénib N-oxyde-d3(M2) 相关抗体:Phospho-PDGFR beta (Y740) AntibodyPDGFR alpha AntibodyPDGF B Antibody (YA1556)PDGFR beta Antibody (YA1925)FMO3 Antibody (YA1992)Phospho-PDGFR beta (Tyr740) Antibody (YA3062)分子量:501.83Formula:C21H12D3ClF4N4O4CAS 号:1333489-03-4非标记 CAS:835621-11-9中文名称:瑞格非尼 N-氧化物(M2代谢物)杂质13-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Allard M, et al. Simultaneous analysis of regorafenib and sorafenib and three of their metabolites in human plasma using LC-MS/MS. J Pharm Biomed Anal

「同位素标记抑制剂」CAS:220803-19-0|N-Acetylneuraminic acid-13C-2

「同位素标记抑制剂」CAS:220803-19-0|N-Acetylneuraminic acid-13C-2

作者:德尔塔生物 日期:2025-06-13

生物活性:N-Acetylneuraminic acid-13C-2 is the 13C labeled N-Acetylneuraminic acid.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.N-Acetylneuraminic acid-13C-2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:310.26Formula:C1013CH19NO9CAS 号:220803-19-0非标记 CAS:131-48-6中文名称:唾液酸-13C-2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacoth

「同位素标记抑制剂」CAS:1032998-24-5|N-Acetylneuraminic acid-13C-1

「同位素标记抑制剂」CAS:1032998-24-5|N-Acetylneuraminic acid-13C-1

作者:德尔塔生物 日期:2025-06-13

生物活性:N-Acetylneuraminic acid-13C-1 is the 13C labeled N-Acetylneuraminic acid.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.N-Acetylneuraminic acid-13C-1 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:310.26Formula:C1013CH19NO9CAS 号:1032998-24-5非标记 CAS:131-48-6中文名称:唾液酸-13C-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacot

「同位素标记抑制剂」CAS:64162-77-2|N-Acetylneuraminic acid-13C

「同位素标记抑制剂」CAS:64162-77-2|N-Acetylneuraminic acid-13C

作者:德尔塔生物 日期:2025-06-13

生物活性:N-Acetylneuraminic acid-13C is the 13C labeled N-Acetylneuraminic acid.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.N-Acetylneuraminic acid-13C 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:310.26Formula:C1013CH19NO9CAS 号:64162-77-2非标记 CAS:131-48-6中文名称:唾液酸-13C运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 201

「同位素标记抑制剂」CAS:1216839-31-4|Indole-2-carboxylic acid-13C

「同位素标记抑制剂」CAS:1216839-31-4|Indole-2-carboxylic acid-13C

作者:德尔塔生物 日期:2025-06-13

生物活性:Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].IC50 & Target:NMDA Receptor体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Indole-2-carboxylic acid-13C 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyPSD95 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNMDAR1 AntibodyNMDAR2A AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin Antibody分子量:162.15Formula:C813CH7NO2CAS 号:1216839-31-4非标记 CAS:1477-50-5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Anal

「同位素标记抑制剂」CAS:1189888-77-4|N-Desmethylclozapine-d8

「同位素标记抑制剂」CAS:1189888-77-4|N-Desmethylclozapine-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:N-Desmethylclozapine-d8 is the deuterium labeled N-Desmethylclozapine. N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist[1][2].IC50 & Target:mAChR1δ Opioid Receptor/DOR体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.N-Desmethylclozapine-d8 相关抗体:S100A10 Antibody (YA675)FMO3 Antibody (YA1992)Muscarinic Acetylcholine receptor M3 AntibodyMuscarinic Acetylcholine Receptor M2 Antibody (YA2610)ING1 Antibody (YA3018)delta Opioid Receptor Antibody (YA3117)kappa Opioid Receptor Antibody (YA3132)分子量:320.85Formula:C17H9D8ClN4CAS 号:1189888-77-4非标记 CAS:6104-71-8性状:固体颜色:White to off-white中文名称:N-去甲基氯氮平 d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (540 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitut