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「同位素标记抑制剂」CAS:1329799-64-5|Piracetam-d8
作者：德尔塔生物 日期：2025-06-13
生物活性：Piracetam-d8 (UCB-6215-d8) is the deuterium labeled Piracetam. Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Piracetam-d8 相关抗体:PSD95 AntibodyNMDAR1 AntibodyNMDAR2A AntibodyIonotropic Glutamate Receptor 2 Antibody (YA1143)GRM5 Antibody (YA1509)Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081)NR2E1 Antibody (YA2648)NR2F2 Antibody (YA1223)KA1 Antibody (YA1879)GRIK2 Antibody (YA2705)PSD93 Antibody (YA3187)分子量：150.21Formula：C6H2D8N2O2CAS 号：1329799-64-5非标记 CAS：7491-74-9中文名称：吡拉西坦 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mingeot-Leclercq, M.P., et al., Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment. Biochi
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「同位素标记抑制剂」CAS:2748541-85-5|Flavoxate-d5
作者：德尔塔生物 日期：2025-06-13
生物活性：Flavoxate-d5 is deuterium labeled Flavoxate.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Flavoxate-d5 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)PDE1B Antibody (YA1553)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)CRCP Antibody (YA3350)Muscarinic Acetylcholine receptor M3 AntibodyAnnexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)PDE4D Antibody (YA1714)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)Muscarinic Acetylcholine Receptor M2 Antibody (YA2610)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)分子量：396.49Formula：C24H20D5NO4CAS 号：2748541-85-5非标记 CAS：15301-69-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)
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「同位素标记抑制剂」CAS:1219803-67-4|Stavudine-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Stavudine-d4 is the deuterium labeled Stavudine. Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis[1][2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Stavudine-d4 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP AntibodyNLRP3 Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyNLRP3 AntibodyAIF Antibody (YA636)ALIX AntibodyCD4 AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 Antibody分子量：228.24Formula：C10H8D4N2O4CAS 号：1219803-67-4非标记 CAS：3056-17-5中文名称：司他夫定 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under t
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「同位素标记抑制剂」CAS:1246819-84-0|Dovitinib-d8
作者：德尔塔生物 日期：2025-06-13
生物活性：Dovitinib-d8 is the deuterium labeled Dovitinib. Dovitinib (CHIR-258) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/FGFR3, VEGFR1/VEGFR2/VEGFR3 and PDGFRα/PDGFRβ, respectively[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dovitinib-d8 相关抗体:FGFR2/CD332 Antibodyc-Kit Antibody (YA502)Phospho-PDGFR beta (Y740) AntibodyVEGF Receptor 2 Antibody (YA014)FGFR1 AntibodyFGFR1 Oncogene Partner AntibodyFGFR2 AntibodyFGFR3 AntibodyPDGFR alpha AntibodyFGF2 AntibodyM-CSF AntibodyVEGF Receptor 1 AntibodyVEGFA AntibodyCSF-1R Antibody (YA1299)VEGF Receptor2 Antibody FGF1 Antibody (YA1430)PDGF B Antibody (YA1556)FGFR4 Antibody (YA1588)PLGF Antibody (YA1812)PDGFR beta Antibody (YA1925)VEGFD Antibody (YA2385)FGF19 Antibody (YA2672)TACC3 Antibody (YA2921)Phospho-PDGFR beta (Tyr740) Antibody (YA3062)FGF21 Antibody (YA3276)G-CSF Antibody (YA3307)c-Kit AntibodySCF AntibodyPGF Antibody (YA1434)Neuropilin 1 Antibody (YA1831)分子量：400.48Formula：C21H13D8FN6OCAS 号：1246819-84-0非标记 CAS：405169-16-6中文名称：多韦替尼 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended cond
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「同位素标记抑制剂」CAS:1398065-50-3|Terconazole-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Terconazole-d4 is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Terconazole-d4 相关抗体:SDHA Antibody分子量：536.49Formula：C26H27D4Cl2N5O3CAS 号：1398065-50-3非标记 CAS：67915-31-5性状：固体颜色：White to off-white中文名称：特康唑 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:2713301-45-0|Ibudilast-d7
作者：德尔塔生物 日期：2025-06-13
生物活性：Ibudilast-d7 is the deuterium labeled Ibudilast. Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ibudilast-d7 相关抗体:PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)PDE4D Antibody (YA1714)分子量：237.35Formula：C14H11D7N2OCAS 号：2713301-45-0非标记 CAS：50847-11-5中文名称：异丁司特 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (540 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mizuno T, et al. Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia. Neuropharmaco
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「同位素标记抑制剂」CAS:1795142-30-1|Methazolamide-d6
作者：德尔塔生物 日期：2025-06-13
生物活性：Methazolamide-d6 is the deuterium labeled Methazolamide. Methazolamide (L584601) is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders[1][2].IC50 & Target：CA Ⅱ体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：242.31Formula：C5H2D6N4O3S2CAS 号：1795142-30-1非标记 CAS：554-57-4中文名称：醋甲唑胺 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (536 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Yang F, et al. HLA-B*59:01: a marker for Stevens-Johnson syndrome/toxic epidermal necrolysis caused by methazolamide in Han Chinese. Pharmacogenomics J. 2016;16(1):83-87. [Content Brief][3]. Abbate F, et al. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with
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「同位素标记抑制剂」CAS:1189700-56-8|Dofetilide-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Dofetilide-d4 is a deuterium labeled Dofetilide. Dofetilide is a class III antiarrhythmic agent.分子量：445.59Formula：C19H23D4N3O5S2CAS 号：1189700-56-8非标记 CAS：115256-11-6性状：固体颜色：White to off-white中文名称：多非利特 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1219805-04-5|Cysteamine-d4 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Cysteamine-d4 (hydrochloride) is the deuterium labeled Cysteamine hydrochloride. Cysteamine hydrochloride (2-Aminoethanethiol hydrochloride) is an orally active agent for the treatment of nephropathic cystinosis and an antioxidant.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cysteamine-d4 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 AntibodyAIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Catalase Antibody (YA552)Catalase Antibody (YA811)CNPase AntibodyCortactin AntibodyCOX IV Antibody分子量：117.63Formula：C2H4D4ClNSCAS 号：1219805-04-5非标记 CAS：156-57-0性状：固体颜色：White to off-white中文名称：半胱胺盐酸盐 d4 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C
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「同位素标记抑制剂」CAS:1189940-96-2|Fenbufen-d9
作者：德尔塔生物 日期：2025-06-13
生物活性：Fenbufen-d9 (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor[1][2][3][4][5].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fenbufen-d9 相关抗体:Cleaved-Caspase 9 AntibodyCleaved-Caspase 1 AntibodyCleaved-Caspase 3 p12 AntibodyCaspase-3 AntibodyCaspase-9 AntibodyCOX2 AntibodyCaspase 7 AntibodyCaspase-10 AntibodyCaspase-14 AntibodyCaspase-6 AntibodyCaspase-6 p18 AntibodyCaspase-8 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCarbonic Anhydrase I AntibodyCARD9 AntibodyCaspase 1 AntibodyCaspase 11 AntibodyCleaved-Caspase 8 AntibodyCOX IV Antibody (YA867)Caspase-12 AntibodyCaspase-1 AntibodyCASP4 AntibodyCaspase-5 p20 AntibodyAPAF1 Antibody (YA1481)NOXA2 Antibody (YA1649)DKC1 Antibody (YA1750)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)FADD Antibody (YA2793)分子量：263.34Formula
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「同位素标记抑制剂」CAS:774596-22-4|Cetirizine-d8
作者：德尔塔生物 日期：2025-06-13
生物活性：Cetirizine-d8 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].IC50 & Target：H1 Receptor分子量：396.94Formula：C21H17D8ClN2O3CAS 号：774596-22-4非标记 CAS：83881-51-0性状：固体颜色：Off-white to light yellow中文名称：左西替利嗪-d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1638885-65-0|Apalutamide-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].分子量：481.46Formula：C21H11D4F4N5O2SCAS 号：1638885-65-0非标记 CAS：956104-40-8性状：固体颜色：White to light yellow中文名称：阿帕鲁胺 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:2254100-49-5|Osimertinib-13C,d3
作者：德尔塔生物 日期：2025-06-13
生物活性：Osimertinib-13C,d3 is the deuterium and 13C labeled Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Osimertinib-13C,d3 相关抗体:c-Fos AntibodyCaveolin-1 AntibodyPhospho-EGFR (Tyr1068) AntibodyPhospho-EGFR (Tyr1173) Antibodyc-Fos Antibody (YA506)EGF AntibodyEGFR AntibodyEGR1 AntibodyPhospholipase C gamma 1 AntibodyPhospho-EGFR (Tyr1068) Antibody (YA204)HER2 AntibodyEGFR Antibody (YA775)HER2 Antibody (YA771)ErbB 4 AntibodyPhospho-EGFR (Tyr1092) AntibodyTGF alpha AntibodyHBEGF Antibody (YA1801)ErbB 3 AntibodyGRB7 Antibody (YA1165)分子量：503.62Formula：C2713CH30D3N7O2CAS 号：2254100-49-5非标记 CAS：1421373-65-0性状：固体颜色：White to off-white中文名称：奥斯替尼 13C,d3；奥希替尼 13C,d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)纯度 & 产品资料纯度： 99.14%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokin
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「同位素标记抑制剂」CAS:1134803-16-9|Imatinib-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Imatinib-d4 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].分子量：497.63Formula：C29H27D4N7OCAS 号：1134803-16-9非标记 CAS：152459-95-5性状：固体颜色：Off-white to light yellow中文名称：伊马替尼 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1383572-19-7|Cabazitaxel-d9
作者：德尔塔生物 日期：2025-06-13
生物活性：Cabazitaxel-d9 is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cabazitaxel-d9 相关抗体:alpha Tubulin AntibodyLC3A/B AntibodyBeta Tubulin Antibodybeta Tubulin Antibody (YA839)Doublecortin AntibodyLC3B Antibody (YA308)Stathmin 1 Antibody (YA049)Stathmin 1 Antibody (YA050)alpha Tubulin (acetyl K40) Antibodybeta III Tubulin Antibodygamma Tubulin AntibodyLC3B AntibodyBeta Tubulin Antibody (HRP) (YA865)Cytokeratin 5 AntibodyMAP2 AntibodyDM1 Antibody (YA898)CK18 AntibodyCytokeratin 19 AntibodyCytokeratin 7 Antibody (YA951)Cytokeratin 15 Antibody (YA1493)p63 Antibody (YA1531)Cytokeratin 6 Antibody (YA1701)Cytokeratin 4 Antibody (YA1762)Cytokeratin 10 Antibody (YA1857)Cytokeratin 14 Antibody (YA1876)Cytokeratin 1 Antibody (YA2665)Stanniocalcin 1 Antibody (YA2690)Cytokeratin 13 Antibody (YA2695)HRH3 Antibody (YA2701)Phospho-alpha Tubulin (Tyr272) Antibody (YA3041)分子量：844.99Formula：C45H48D9NO14CAS 号：1383572-19-7非标记 CAS：183133-96-2性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式
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