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「同位素标记抑制剂」CAS:1173018-93-3|3-Methylxanthine-13C4,15N3
作者：德尔塔生物 日期：2025-06-13
生物活性：3-Methylxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled 3-Methylxanthine. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.3-Methylxanthine-13C4,15N3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：173.09Formula：C213C4H6N15N3O2CAS 号：1173018-93-3非标记 CAS：1076-22-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (544 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2)
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「同位素标记抑制剂」CAS:2673270-26-1|Montelukast-d6 sodium
作者：德尔塔生物 日期：2025-06-13
生物活性：Montelukast-d6 (sodium) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Montelukast-d6 sodium 相关抗体:Leukotriene A4 Hydrolase Antibody (YA2400)分子量：614.20Formula：C35H29D6ClNNaO3SCAS 号：2673270-26-1非标记 CAS：151767-02-1性状：固体颜色：White to off-white中文名称：孟鲁司特钠 d6 (钠盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： ≥96.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Pu S, et, al. Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury. Front Pharmacol. 2019 Sep 18; 10:1070.;William RHJ, et, al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med. 2002 Jan 1; 165(1): 108-16. [Content Brief]
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「同位素标记抑制剂」CAS:2006272-96-2|β-Caryophyllene-d2
作者：德尔塔生物 日期：2025-06-13
生物活性：β-Caryophyllene-d2 is deuterium labeled β-Caryophyllene. β-Caryophyllene is a CB2 receptor agonist.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.β-Caryophyllene-d2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：206.36Formula：C15H22D2CAS 号：2006272-96-2非标记 CAS：87-44-5性状：油状物颜色：Colorless to light yellow中文名称：β-石竹烯-d2；β-丁香烯-d2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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「同位素标记抑制剂」CAS:2041095-50-3|Filgotinib-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Filgotinib-d4 is the deuterium labeled Filgotinib. Filgotinib (GLPG0634) is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Filgotinib-d4 相关抗体:Phospho-JAK2 (Tyr1007/1008) AntibodyJAK1 Antibody (YA722)JAK1 AntibodyJAK2 Antibody (YA721)Phospho-JAK2 (Tyr1007+Tyr1008) AntibodyJAK2 Antibody (YA330)Phospho-JNK (Thr183) AntibodyJAK3 Antibody (YA2466)分子量：429.53Formula：C21H19D4N5O3SCAS 号：2041095-50-3非标记 CAS：1206161-97-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Van Rompaey L, et al. Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases. J Immunol. 2013, 191(7), 3568-3577. [Content Brief][3]. Menet CJ, et al. Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634. J Med Chem. 2014 Nov 17. [Content Brief]
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「同位素标记抑制剂」CAS:1794810-59-5|Bambuterol-d9 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Bambuterol-d9 (hydrochloride) is the deuterium labeled Bambuterol. Bambuterol ((±)-Bambuterol) hydrochloride is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Bambuterol-d9 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：412.96Formula：C18H21D9ClN3O5CAS 号：1794810-59-5非标记 CAS：81732-65-2性状：固体颜色：White to off-white中文名称：班布特罗盐酸盐-d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:1353867-92-1|Albendazole-d3
作者：德尔塔生物 日期：2025-06-13
生物活性：Albendazole-d3 is the deuterium labeled Albendazole, which is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations[1].分子量：268.35Formula：C12H12D3N3O2SCAS 号：1353867-92-1非标记 CAS：54965-21-8性状：固体颜色：White to off-white中文名称：阿苯达唑 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1189469-46-2|Loperamide-d6 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Loperamide-d6 (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea[1].分子量：519.54Formula：C29H28D6Cl2N2O2CAS 号：1189469-46-2非标记 CAS：34552-83-5性状：固体颜色：White to off-white中文名称：盐酸洛哌丁胺 d6 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:70711-53-4|Phenindione-d5
作者：德尔塔生物 日期：2025-06-13
生物活性：Phenindione-d5 is deuterium labeled Phenindione, which is an anticoagulant which functions as a Vitamin K antagonist.分子量：227.27Formula：C15H5D5O2CAS 号：70711-53-4非标记 CAS：83-12-5性状：固体颜色：White to off-white中文名称：苯茚二酮 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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「同位素标记抑制剂」CAS:1356922-29-6|Enalaprilat-d5 sodium
作者：德尔塔生物 日期：2025-06-13
生物活性：Enalaprilat-d5 (sodium) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.分子量：397.39Formula：C18H17D5N2Na2O5CAS 号：1356922-29-6性状：固体颜色：White to off-white中文名称：依那普利拉钠 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:1392208-04-6|(Rac)-Ropivacaine-d7
作者：德尔塔生物 日期：2025-06-13
生物活性：(Rac)-Ropivacaine-d7 is the deuterium labeled (Rac)-Ropivacaine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Ropivacaine-d7 相关抗体:xCT Antibody (YA006)xCT Antibody (YA652)ATP1A1 AntibodyAlpha-ENaC AntibodyLGI1 Antibody (YA2885)CRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)Cardiac Troponin C Antibody (YA2125)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)CRMP4 Antibody (YA2777)Kir2.1 Antibody (YA2871)分子量：281.44Formula：C17H19D7N2OCAS 号：1392208-04-6非标记 CAS：84057-95-4中文名称：罗哌卡因 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:1346606-66-3|Clomifene-d5 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Clomifene-d5 (hydrochloride) is a deuterium labeled Clomifene. Clomifene is an orally active compound used for infertility. Clomifene is a simple, relatively safe, easily administered and well-tolerated efficacious compound to induce ovulation[1].分子量：447.45Formula：C26H24D5Cl2NOCAS 号：1346606-66-3非标记 CAS：911-45-5性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： 98.53%参考文献[1]. Wilkes S, et al. Ovulation induction with clomifene: a primary care perspective. J Fam Plann Reprod Health Care. 2012;38(1):48-52. [Content Brief]
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「同位素标记抑制剂」CAS:2714316-71-7|Zuclomiphene-d4 citrate
作者：德尔塔生物 日期：2025-06-13
生物活性：Zuclomiphene-d4 (citrate) is a deuterium labeled Zuclomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[1][2][3][4].分子量：602.11Formula：C32H32D4ClNO8CAS 号：2714316-71-7非标记 CAS：7619-53-6性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:2070009-63-9|Ivabradine-d6 hydrochloride
作者：德尔塔生物 日期：2025-06-13
生物活性：Ivabradine-d6 (hydrochloride) is the deuterium labeled Ivabradine hydrochloride. Ivabradine hydrochloride is a new If inhibitor with IC50 of 2.9 μM, and used as a pure heart rate lowering agent.分子量：511.08Formula：C27H31D6ClN2O5CAS 号：2070009-63-9非标记 CAS：148849-67-6性状：固体颜色：White to off-white中文名称：盐酸伊伐布雷定 d6 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1185995-18-9|Pentoxifylline-d5
作者：德尔塔生物 日期：2025-06-13
生物活性：Pentoxifylline-d5 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pentoxifylline-d5 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)PDE4D Antibody (YA1714)Tat SF1 Antibody (YA2886)分子量：283.34Formula：C13H13D5N4O3CAS 号：1185995-18-9非标记 CAS：6493-05-6性状：固体颜色：White to off-white中文名称：己酮可可碱 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:557794-38-4|Dapsone-d8
作者：德尔塔生物 日期：2025-06-13
生物活性：Dapsone-d8 is a deuterium labeled Dapsone. Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with antibacterial, antigenic and anti-inflammatory activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone can be used as an anticonvulsant and also in the research of skin and glioblastoma diseases[2][3][4][5].体外研究(In Vitro)：氨苯砜 (0.06 mM; 30 min) 抑制 N-Formyl-Met-Leu-Phe.html" class="link-product" target="_blank">N-Formyl-Met-Leu-Phe (HY-P0224) (1 μM) 和生理激动剂 C5a (100 nM) 触发的细胞内外超氧化物 (O2-) 和胰蛋白酶 E 的释放，而不是对 Phorbol 12-myristate 13-acetate.html" class="link-product" target="_blank">Phorbol 12-myristate 13-acetate (HY-18739) (100 nM) 没有作用[5]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dapsone-d8 相关抗体:Catalase Antibody (YA552)Catalase Antibody (YA811)MRP2 AntibodyC Reactive Protein Antibody (YA941)Elongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)PARK7/DJ1 Antibody (YA1799)Sulfadimidine Antibody (YA906)C Reactive Protein Antibody (YA939)C Reactive Protein Antibody (YA940)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)PON1 Antibody (YA1666)PON2 Antibody (YA1688)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Anti
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