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MPP+-d3 iodide「同位素标记抑制剂」

MPP+-d3 iodide「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:MPP+-d3 (iodide) is deuterium labeled MPP+ (iodide). MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.MPP+-d3 iodide 相关抗体:Parkin AntibodyMCU AntibodyMitofusin 2 AntibodyLIAS AntibodyNDUFS8 Antibody (YA1352)TOMM20 Antibody (YA1380)NUDT9 Antibody (YA1453)CPS1 Antibody (YA1661)Complex III Subunit 5 Antibody (YA1865)NDUFB8 Antibody (YA1947)MFF Antibody (YA2012)NDUFS4 Antibody (YA2072)MT ND1 Antibody (YA2089)Mitochondrial Fission 1 Protein Antibody (YA2098)Cyclophilin 40 Antibody (YA2099)TIMM44 Antibody (YA2207)NDUFS1 Antibody (YA2535)CLPX Antibody (YA2814)MTCO2 Antibody (YA3254)Mitochondrial Ferritin Antibody (YA3353)mtTFA Antibody (YA3360)Mitofusin 1 AntibodyOrnithine Carbamoyltransferase/OTC Antibody (YA1230)NDUFB10 Antibody (YA1330)NDUFB11 Antibody (YA1

Decyltrimethylammonium-d21 bromide「同位素标记抑制剂」

Decyltrimethylammonium-d21 bromide「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:N,N,N-Trimethyldecan-1-aminium-d21 bromide is the deuterium labeled N,N,N-Trimethyldecan-1-aminium bromide[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:301.42Formula:C13H9D21BrNCAS 号:1515861-67-2非标记 CAS:2082-84-0性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Sodium 3-methyl-2-oxobutanoate-d7「同位素标记抑制剂」

Sodium 3-methyl-2-oxobutanoate-d7「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Sodium 3-methyl-2-oxobutanoate-d7 is the deuterium labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sodium 3-methyl-2-oxobutanoate-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:145.14Formula:C5D7NaO3CAS 号:2483831-46-3非标记 CAS:3715-29-5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et

Methyl tetradecanoate-d27,Myristic acid methyl ester-d27「同位素标记抑制剂」

Methyl tetradecanoate-d27,Myristic acid methyl ester-d27「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Methyl tetradecanoate-d27 is the deuterium labeled Methyl myristate. Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:269.56Formula:C15H3D27O2CAS 号:434349-93-6非标记 CAS:124-10-7性状:液体颜色:Colorless to off-white中文名称:五甲基呋喃溴酸酯 d27运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

Tempo-d18「同位素标记抑制剂」

Tempo-d18「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Tempo-d18 is the deuterium labeled Tempo[1]. Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects[2][3][4][5].细胞效力(Cellular Effect)A-431Cell Line TypeValueDescriptionReferencesA-431IC50> 300 μMCompound: TEMPOCytotoxicity against human A431 cells after 72 hrs by MTT assayCytotoxicity against human A431 cells after 72 hrs by MTT assay[PMID: 22309911]体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Tempo-d18 相关抗体:Ctip2 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyParkin AntibodyRPA32 Antibody (YA679)Catalase Antibody (YA552)Catalase Antibody (YA811)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyMCU AntibodyNanog AntibodyNucleolin AntibodyPCNA AntibodyPDX1 AntibodyRbBP5 AntibodyS100A4 AntibodySP1 AntibodyBRCA1 Antibody (YA819)Argonaute 2 AntibodyBRCA1 AntibodyElongation Factor 1A1 AntibodyKAP1 AntibodyMCM2 Antibody (YA705)Mitofusin 2 AntibodyMLH1 Antibody (YA703)分子量:174.36Formula:C9D18NOCAS

Colfosceril miristate-d9,DMPC-d9;  1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9「同位素标记抑制剂」

Colfosceril miristate-d9,DMPC-d9; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Colfosceril miristate-d9 (DMPC-d9) is deuterium labeled Colfosceril miristate. Colfosceril miristate a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:686.99Formula:C36H63D9NO8PCAS 号:71479-88-4非标记 CAS:18194-24-6性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

1-Iodoethane-1,1,2,2,2-d5,Iodoethane-d5「同位素标记抑制剂」

1-Iodoethane-1,1,2,2,2-d5,Iodoethane-d5「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:1-Iodoethane-1,1,2,2,2-d5 is the deuterium labeled 1-Iodoethane[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:161.00Formula:C2D5ICAS 号:6485-58-1非标记 CAS:75-03-6性状:液体(密度:2.013 g/cm3)颜色:Colorless to light yellow中文名称:氘代碘乙烷运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.58%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Fenoterol-d6 hydrobromide,非诺特罗氢溴酸盐 d6 (氢溴酸盐「同位素标记抑制剂」

Fenoterol-d6 hydrobromide,非诺特罗氢溴酸盐 d6 (氢溴酸盐「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Fenoterol-d6 (hydrobromide) (Th-1165a-d6) is the deuterium labeled Fenoterol hydrobromide. Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fenoterol-d6 hydrobromide 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量:390.30Formula:C17H16D6BrNO4CAS 号:1286129-04-1非标记 CAS:1944-12-3性状:固体颜色:Off-white to light green中文名称:非诺特罗氢溴酸盐 d6 (氢溴酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

Mono-(2-ethylhexyl phthalate-d4,MEHP-d4;  Phthalic acid mono-2-ethylhexyl ester-d4「同位素标记抑制剂」

Mono-(2-ethylhexyl phthalate-d4,MEHP-d4; Phthalic acid mono-2-ethylhexyl ester-d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Mono-(2-ethylhexyl) phthalate-d4 is a deuterium labeled Mono-(2-ethylhexyl) phthalate (HY-W018392). Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD)[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Mono-(2-ethylhexyl) phthalate-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:282.37Formula:C16H18D4O4CAS 号:1276197-22-8非标记 CAS:4376-20-9性状:液体(密度:1.1±0.1 g/cm3)颜色:Colorless to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 years,4°C:2 yearsIn sol

Methyl Paraben-13C6,Methyl 4-hydroxybenzoate-13C6「同位素标记抑制剂」

Methyl Paraben-13C6,Methyl 4-hydroxybenzoate-13C6「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Methyl Paraben-13C6 (Methyl 4-hydroxybenzoate-13C6) is a 13C labeled Methyl Paraben (HY-N0349)[1]. Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Methyl Paraben-13C6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:158.10Formula:C213C6H8O3CAS 号:1581694-95-2非标记 CAS:99-76-3性状:固体颜色:White to off-white中文名称:尼泊金甲酯-13C6; 对羟基苯甲酸甲酯-13C6运输条件:Room temperature in continental US; m

5-Hydroxymethylfurfural-13C6,5-羟甲基糠醛-13C6; 2-Hydroxymethyl-5-furfural-13C6; 2-Formyl-5-hydroxymethylfuran-13C6「同位素标记抑制剂」

5-Hydroxymethylfurfural-13C6,5-羟甲基糠醛-13C6; 2-Hydroxymethyl-5-furfural-13C6; 2-Formyl-5-hydroxymethylfuran-13C6「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:5-Hydroxymethylfurfural-13C6 (2-Hydroxymethyl-5-furfural-13C6; 2-Formyl-5-hydroxymethylfuran-13C6) is a 13C labeled 5-Hydroxymethylfurfural (HY-Y0051). 5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors.体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.5-Hydroxymethylfurfural-13C6 相关抗体:SDHA Antibody分子量:132.07Formula:13C6H6O3CAS 号:1219193-98-2非标记 CAS:67-47-0性状:固体颜色:White to off-white中文名称:5-羟甲基糠醛-13C6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

3-Hydroxybutyric acid-13C4 sodium,3-羟基丁酸钠-13C4; β-Hydroxybutyric acid-13C4 sodium「同位素标记抑制剂」

3-Hydroxybutyric acid-13C4 sodium,3-羟基丁酸钠-13C4; β-Hydroxybutyric acid-13C4 sodium「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:3-Hydroxybutyric acid-13C4 (sodium) is the 13C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids[1].分子量:130.06Formula:13C4H7NaO3CAS 号:287111-43-7非标记 CAS:150-83-4性状:固体颜色:White to off-white中文名称:3-羟基丁酸钠-13C4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Thymine-d4-1「同位素标记抑制剂」

Thymine-d4-1「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Thymine-d4-1 is the deuterium labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Thymine-d4-1 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:130.14Formula:C5H2D4N2O2CAS 号:156054-85-2非标记 CAS:65-71-4性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

Octacosane-d58,n-Octacosane-d58; NSC 5549-d58「同位素标记抑制剂」

Octacosane-d58,n-Octacosane-d58; NSC 5549-d58「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Octacosane-d58 is the deuterium labeled Octacosane[1]. Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l[2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Octacosane-d58 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:453.12Formula:C28D58CAS 号:16416-33-4性状:固体颜色:White to off-white中文名称:二十八烷-d58运输条件:Room temperature

Nicorandil-d4,尼可地尔 d4「同位素标记抑制剂」

Nicorandil-d4,尼可地尔 d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Nicorandil-d4 (SG-75-d4) is the deuterium labeled Nicorandil. Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K+ channels and cardiac ATP-sensitive K+ channels (KATP). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nicorandil-d4 相关抗体:ATP1A1 AntibodyLGI1 Antibody (YA2885)Cardiac Troponin C Antibody (YA2125)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)分子量:215.20Formula:C8H5D4N3O4CAS 号:1132681-23-2非标记 CAS:65141-46-0性状:固体颜色:White to off-white中文名称:尼可地尔 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.81%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mitsuhiko Yamada, et al. The nucleotide-binding domains of sulfonylurea receptor 2A and 2B play different functional role