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Melitracen-d6 hydrochloride,盐酸美力他欣 d6 (盐酸盐「同位素标记抑制剂」

Melitracen-d6 hydrochloride,盐酸美力他欣 d6 (盐酸盐「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Melitracen-d6 (hydrochloride) is the deuterium labeled Melitracen hydrochloride. Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Melitracen-d6 hydrochloride 相关抗体:MTNR1A Antibody分子量:333.93Formula:C21H20D6ClNCAS 号:1189648-08-5非标记 CAS:10563-70-9中文名称:盐酸美力他欣 d6 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Xiaoqian Zhou , et al. The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis. Gastroenterol Res Pract. 2019 Feb 28;2019:3480732. [Content Brief][3]. K Shimamoto, et al. Myriatic E

Molindone-d8,盐酸吗啉吲酮-d8; (±-Molindone-d8; SPN-810M-d8「同位素标记抑制剂」

Molindone-d8,盐酸吗啉吲酮-d8; (±-Molindone-d8; SPN-810M-d8「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Molindone-d8 is the deuterium labeled Molindone. Molindone hydrochloride (EN-1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Molindone-d8 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量:284.42Formula:C16H16D8N2O2CAS 号:1189805-13-7非标记 CAS:7416-34-4性状:固体颜色:Off-white to light yellow中文名称:盐酸吗茚酮-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.2%参考文献[1]. Yu C, et al. In vitro pharmacological characterization of SPN-810M (molindone). J Exp Pharmacol. 2018;10:65-73. Published 2018 Nov 21. [Content Brief][2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Nevirapine-d3,奈韦拉平 d3「同位素标记抑制剂」

Nevirapine-d3,奈韦拉平 d3「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Nevirapine-d3 (BI-RG 587-d3) is the deuterium labeled Nevirapine. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nevirapine-d3 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:269.32Formula:C15H11D3N4OCAS 号:1051419-24-9非标记 CAS:129618-40-2中文名称:奈韦拉平 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Erickson DA, et al. Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitornevirapine by human hepatic cytochromes P-450. Drug Metab Dispos. 1999 Dec;27(12):1488-95. [Content Brief][3]. Dong JJ, et al. In vitro evaluation of the therapeutic potential of nevirapine in treatment of

(E/Z-Capsaicin-d3,辣椒素 d3「同位素标记抑制剂」

(E/Z-Capsaicin-d3,辣椒素 d3「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:(E/Z)-Capsaicin-d3 is the deuterium labeled (E/Z)-Capsaicin[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(E/Z)-Capsaicin-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 AntibodyAIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)CNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 Antibody分子量:308.43Formula:C18H24D3NO3CAS 号:1185237-43-7非标记 CAS:7553-53-9中文名称:辣椒素 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (516 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Br

Pamapimod-d4「同位素标记抑制剂」

Pamapimod-d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Pamapimod-d4 (Ro4402257-d4) is the deuterium labeled Pamapimod. Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38α and p38β, respectively. Pamapimod has no activity against p38δ or p38γ isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pamapimod-d4 相关抗体:p38 AntibodyPhospho-p38 (Thr180/Tyr182) AntibodyASK1 Antibody (YA609)MAPK14 AntibodyATF2 Antibodyp38 Antibody (YA696)Phospho-ATF2 (Thr71) AntibodyPhospho-MSK1 (Ser360) Antibodyp38 MAPK AntibodyGADD45A Antibody (YA1076)RRAS Antibody (YA3212)MAPKAP Kinase 2 AntibodyPhospho-MSK1 (Ser376) AntibodyMAP2K6 Antibody (YA1088)p40 Antibody (YA1500)PCPTP1 Antibody (YA1549)Sprouty 2 Antibody (YA1604)Sprouty 4 Antibody (YA1780)MAPKAP Kinase 3 Antibody (YA3070)MAPK6 Antibody (YA3194)分子量:410.41Formula:C19H16D4F2N4O4CAS 号:1246814-57-2非标记 CAS:449811-01-2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 K

Lansoprazole sulfide-d4,AG-1777-d4「同位素标记抑制剂」

Lansoprazole sulfide-d4,AG-1777-d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].IC50 & Target:Proton pump[1]IC50: 0.59 µM (Mycobacterium tuberculosis intracellularly), 0.46 µM (Mycobacterium tuberculosis in broth)[1]分子量:357.39Formula:C16H10D4F3N3OSCAS 号:1216682-38-0非标记 CAS:103577-40-8性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: ≥99.0%参考文献[1]. Mdanda S, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12). [Content Brief]

Pyrazine-d4,1,4-Diazine-d4「同位素标记抑制剂」

Pyrazine-d4,1,4-Diazine-d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Pyrazine-d4 is the deuterium labeled Pyrazine[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pyrazine-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:84.11Formula:C4D4N2CAS 号:1758-62-9非标记 CAS:290-37-9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Metaxalone-d6,美他沙酮-d6; AHR438-d6; NSC170959-d6「同位素标记抑制剂」

Metaxalone-d6,美他沙酮-d6; AHR438-d6; NSC170959-d6「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Metaxalone-d6 is deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia[1][2][3].IC50 & Target:PPARγ and MAO-A[2]体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Metaxalone-d6 相关抗体:NF-KB p65 AntibodyPhospho-NF-KB p65 (Ser536) AntibodyPhospho-NF-κB p65 (Ser529) AntibodyNF-KB p65 Antibody (YA267)NF-KB p105/p50 AntibodyRelB AntibodyRet AntibodyRetinoic Acid Receptor alpha AntibodySOD2 Antibody (YA071)SOX1 AntibodyTRAF2 AntibodyAnnexin A1 Antibody (YA832)DDX3 Antibody (YA784)NF-KB p100 AntibodyNF-KB p105 Antibody (YA700)Nrf1 AntibodyPGC1 alpha AntibodyPhospho-NF-KB p65 (Thr254) AntibodySOD2 Antibody (YA670)TRAF6 AntibodyPhospho-NFKB1(Ser337) Antibody Nrf2 Antibody(YA895)DDIT3 AntibodyPhospho-NF-κB p65 (Ser536) Antibodyc-Rel AntibodyAnnexin A10 Antibody

Metaxalone-d3,美他沙酮 d3「同位素标记抑制剂」

Metaxalone-d3,美他沙酮 d3「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Metaxalone-d3 is the deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia[1][2][3][4].IC50 & Target:PPARγ and MAO-A[4]体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Metaxalone-d3 相关抗体:NF-KB p65 AntibodyPhospho-NF-KB p65 (Ser536) AntibodyPhospho-NF-κB p65 (Ser529) AntibodyNF-KB p65 Antibody (YA267)NF-KB p105/p50 AntibodyRelB AntibodyRet AntibodyRetinoic Acid Receptor alpha AntibodySOD2 Antibody (YA071)SOX1 AntibodyTRAF2 AntibodyAnnexin A1 Antibody (YA832)DDX3 Antibody (YA784)NF-KB p100 AntibodyNF-KB p105 Antibody (YA700)Nrf1 AntibodyPGC1 alpha AntibodyPhospho-NF-KB p65 (Thr254) AntibodySOD2 Antibody (YA670)TRAF6 AntibodyPhospho-NFKB1(Ser337) Antibody Nrf2 Antibody(YA895)DDIT3 AntibodyPhospho-NF-κB p65 (Ser536) Antibodyc-Rel AntibodyAnnexin A10 A

3-Aminobenzoic acid-d4,m-Aminobenzoic acid-d4;  3ABA-d4「同位素标记抑制剂」

3-Aminobenzoic acid-d4,m-Aminobenzoic acid-d4; 3ABA-d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:3-Aminobenzoic acid-d4 is the deuterium labeled 3-Aminobenzoic acid[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.3-Aminobenzoic acid-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:141.16Formula:C7H3D4NO2CAS 号:78399-79-8非标记 CAS:99-05-8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content

Tetradecyltrimethylammonium-d38 bromide,TTAB-d38 ;  TTABr-d38 ;  MiTMAB-d38「同位素标记抑制剂」

Tetradecyltrimethylammonium-d38 bromide,TTAB-d38 ; TTABr-d38 ; MiTMAB-d38「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Tetradecyltrimethylammonium-d38 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide)[1]. Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure[2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:374.63Formula:C17D38BrNCAS 号:95523-72-1非标记 CAS:1119-97-7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Dopierala K, et al. The effect of molecular structure on the surface properties of selected quaternary ammonium salts. J Colloid Interface Sci. 2008;321(1):220-226. [Content Brief][3]. N. Gorski, et al. Mixtures of Nonionic and Ionic Surfactants. The Effect of Counterion Binding in Mixtures of Tetradecyldimethylamine Oxide and Tetradecyltrimethylammonium Bromide. Langmuir 1994, 10, 8, 2594-2603.[4]. Cocke DL, et al. The surface properties of tetradecyltrimethylammonium

Tetradecyltrimethylammonium-d29 bromide,TTAB-d29;  TTABr-d29;  MiTMAB-d29「同位素标记抑制剂」

Tetradecyltrimethylammonium-d29 bromide,TTAB-d29; TTABr-d29; MiTMAB-d29「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Tetradecyltrimethylammonium-d29 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide)[1]. Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure[2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:365.57Formula:C17H9D29BrNCAS 号:95523-73-2非标记 CAS:1119-97-7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Dopierala K, et al. The effect of molecular structure on the surface properties of selected quaternary ammonium salts. J Colloid Interface Sci. 2008;321(1):220-226. [Content Brief][3]. N. Gorski, et al. Mixtures of Nonionic and Ionic Surfactants. The Effect of Counterion Binding in Mixtures of Tetradecyldimethylamine Oxide and Tetradecyltrimethylammonium Bromide. Langmuir 1994, 10, 8, 2594-2603.[4]. Cocke DL, et al. The surface properties of tetradecyltrimethylammoni

Aflatoxin B1-13C17,黄曲霉毒素B1-13C17「同位素标记抑制剂」

Aflatoxin B1-13C17,黄曲霉毒素B1-13C17「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Aflatoxin B1-13C17 is 13C- and 15N-labeled Aflatoxin B1 (HY-N6615). Aflatoxin B1 (AFB1) is a Group 1A carcinogen and a secondary metabolite produced by Aspergillus flavus and Aspergillus parasiticus. Aflatoxin B1 (AFB1) primarily induces mutations by causing a G to T transversion at the third nucleotide of codon 249 in the tumor suppressor gene p53. In the body, Aflatoxin B1 (AFB1) can cause damage to the intestines and kidneys and has some teratogenic effects[1].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:329.15Formula:13C17H12O6CAS 号:1217449-45-0非标记 CAS:1162-65-8性状:液体颜色:Colorless to light yellow中文名称:黄曲霉毒素B1-13C17运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料纯度: 99.90%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Aflatoxin M1-13C17,黄曲霉毒素 M1-13C17「同位素标记抑制剂」

Aflatoxin M1-13C17,黄曲霉毒素 M1-13C17「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Aflatoxin M1-13C17 is the 13C labeled Aflatoxin M1 (HY-N6699)[1]. Aflatoxin M1 is a major metabolite of Aflatoxin B1. Aflatoxin M1 is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus. The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:345.15Formula:13C17H12O7CAS 号:2707441-97-0非标记 CAS:6795-23-9中文名称:黄曲霉毒素 M1-13C17运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (542 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief][2]. Kumar P, et al. Aflatoxins: A Global Concern for Food Safety, Human Health and Their Management. Front Microbiol. 2017 Jan 17;7:2170. [Content Brief]

Aflatoxin B2-13C17,黄曲霉毒素 B2-13C17「同位素标记抑制剂」

Aflatoxin B2-13C17,黄曲霉毒素 B2-13C17「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-06-06

生物活性:Aflatoxin B2-13C17 is 13C- and 15N-labeled Aflatoxin B2 (HY-N6696). Aflatoxin B2 is a major naturally produced aflatoxin. Aflatoxin B2 is a mycotoxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus.The level of toxicity associated with Aflatoxin is Aflatoxin B1>Aflatoxin M1>Aflatoxin G1>Aflatoxin B2>Aflatoxin M2>Aflatoxin G2[1][2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:331.16Formula:13C17H14O6CAS 号:1217470-98-8非标记 CAS:7220-81-7中文名称:黄曲霉毒素 B2-13C17运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (544 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]