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「同位素标记抑制剂」CAS:1246816-14-7|Melamine-15N3,13C3
作者：德尔塔生物 日期：2025-06-09
生物活性：Melamine-15N3,13C3 is a 13C- and 15N-labeled Melamine (HY-Y1117). Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[1][2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Melamine-15N3,13C3 相关抗体:FMO3 Antibody (YA1992)分子量：132.08Formula：13C3H6N315N3CAS 号：1246816-14-7非标记 CAS：108-78-1性状：固体颜色：White to off-white中文名称：三聚氰胺-13C3,15N3；密胺-13C3,15N3；三聚氰酰胺-13C3,15N3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)纯度 & 产品资料纯度： 96.08%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief][2]. Melamine
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「同位素标记抑制剂」CAS:1332075-41-8|H-HoArg-OH-d4
作者：德尔塔生物 日期：2025-06-09
生物活性：H-HoArg-OH-d4 is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.H-HoArg-OH-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：192.25Formula：C7H12D4N4O2CAS 号：1332075-41-8非标记 CAS：1483-01-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief][2]. Fishman W, et al. L-homoarginine; an inhibitor of
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「同位素标记抑制剂」CAS:1216616-31-7|Flucytosine-13C,15N2
作者：德尔塔生物 日期：2025-06-09
生物活性：Flucytosine-13C,15N2 (NSC 103805-13C,15N2; Ro 2-9915-13C,15N2) is a 13C- and 15N-labeled Flucytosine (HY-B0139).体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Flucytosine-13C,15N2 相关抗体:SDHA Antibody分子量：132.07Formula：C313CH4FN15N2OCAS 号：1216616-31-7非标记 CAS：2022-85-7性状：固体颜色：White to off-white中文名称：氟胞嘧啶-13C,15N2；5-氟胞嘧啶-13C,15N2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)纯度 & 产品资料纯度： 98.06%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246. [Content Brief][2]. Vermes A, et al. Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions. J Antimicrob Chemother. 2000 Aug;46(2):171-9. [Content Brief][3]. Te Dorsthorst DT, et al. In vitro interaction of flucytosine combined with amphotericin B or fluconazole against thirty-five yeast isolates determined by both the fractional inhibitory concentration index and the response surface approach. Antimicrob Agents Chemother. 2002 Sep;46(9):2982-9. [Content Brief]
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「同位素标记抑制剂」CAS:1217632-04-6|Neopterin-13C5
作者：德尔塔生物 日期：2025-06-09
生物活性：Neopterin-13C5 (D-(+)-Neopterin-13C5; D-erythro-Neopterin-13C5) is the deuterium labeled Neopterin (HY-W040055)[1]. Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation[2].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Neopterin-13C5 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：258.18Formula：C413C5H11N5O4CAS 号：1217632-04-6非标记 CAS：2009-64-5性状：固体颜色：White to light yellow中文名称：新蝶呤-13C5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)纯度 & 产品资料纯度： 97.53%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Ph
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「同位素标记抑制剂」CAS:1227162-34-6|Lenalidomide-d5
作者：德尔塔生物 日期：2025-06-09
生物活性：Lenalidomide-d5 is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].IC50 & Target：Cereblon体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lenalidomide-d5 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase An
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「同位素标记抑制剂」CAS:1189649-47-5|Oxprenolol-d7 hydrochloride
作者：德尔塔生物 日期：2025-06-09
生物活性：Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Oxprenolol-d7 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：308.85Formula：C15H17D7ClNO3CAS 号：1189649-47-5非标记 CAS：6452-73-9性状：固体颜色：White to off-white中文名称：盐酸氧烯洛尔 d7 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:203784-52-5|Nortriptyline-d3 hydrochloride
作者：德尔塔生物 日期：2025-06-09
生物活性：Nortriptyline-d3 (hydrochloride) is the deuterium labeled Nortriptyline hydrochloride. Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nortriptyline-d3 hydrochloride 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：302.86Formula：C19H19D3ClNCAS 号：203784-52-5非标记 CAS：894-71-3性状：固体颜色：White to off-white中文名称：盐酸去甲替林 d3 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture
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「同位素标记抑制剂」CAS:64717-35-7|Propantheline-d3 bromide
作者：德尔塔生物 日期：2025-06-09
生物活性：Propantheline-d3 (bromide) is the deuterium labeled Propantheline bromide. Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Propantheline-d3 bromide 相关抗体:Muscarinic Acetylcholine receptor M3 AntibodyMuscarinic Acetylcholine Receptor M2 Antibody (YA2610)分子量：451.41Formula：C23H27D3BrNO3CAS 号：64717-35-7非标记 CAS：50-34-0性状：固体颜色：Off-white to light yellow中文名称：普鲁本辛 d3 (溴盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:1185117-79-6|Climbazole-d4
作者：德尔塔生物 日期：2025-06-09
生物活性：Climbazole-d4 is the deuterium labeled Climbazole. Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Climbazole-d4 相关抗体:SDHA Antibody分子量：296.79Formula：C15H13D4ClN2O2CAS 号：1185117-79-6非标记 CAS：38083-17-9性状：固体颜色：White to off-white中文名称：氯咪巴唑 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:94513-92-5|Nadolol-d9
作者：德尔塔生物 日期：2025-06-09
生物活性：Nadolol-d9 is the deuterium labeled Nadolol. Nadolol is a non-selective and orally active β-adrenergic receptors blocker[1].分子量：318.46Formula：C17H18D9NO4CAS 号：94513-92-5非标记 CAS：42200-33-9性状：固体颜色：Off-white to light yellow中文名称：纳多洛尔 d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1185039-30-8|Gliclazide-d4
作者：德尔塔生物 日期：2025-06-09
生物活性：Gliclazide-d4 (S1702 D4) is the deuterium labeled Gliclazide. Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Gliclazide-d4 相关抗体:ATP1A1 AntibodyLGI1 Antibody (YA2885)Cardiac Troponin C Antibody (YA2125)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)分子量：327.44Formula：C15H17D4N3O3SCAS 号：1185039-30-8非标记 CAS：21187-98-4性状：固体颜色：White to off-white中文名称：格列齐特 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1398066-08-4|Urapidil-d3
作者：德尔塔生物 日期：2025-06-09
生物活性：Urapidil-d3 is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Urapidil-d3 相关抗体:ADRB2 AntibodyMTNR1A AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量：390.49Formula：C20H26D3N5O3CAS 号：1398066-08-4非标记 CAS：34661-75-1性状：固体颜色：White to off-white中文名称：乌拉地尔 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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「同位素标记抑制剂」CAS:1189657-87-1|Probenecid-d14
作者：德尔塔生物 日期：2025-06-09
生物活性：Probenecid-d14 is the deuterium labeled Probenecid. Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Probenecid-d14 相关抗体:CD4 AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)TARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)TRPM8 Antibody (YA1609)TRPM7 Antibody (YA2391)SV40 T Antigen Antibody (YA3256)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)CLEC12A Antibody (YA1419)TrpC1 Antibody (YA1814)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)Tat SF1 Antibody (YA2886)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：299.45Formula：C13H5D14NO4SCAS 号：1189657-87-1非标记 CAS：57-66-9性状：固体颜色：White to off-white中文名称：丙磺舒 d14运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent
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「同位素标记抑制剂」CAS:1398065-86-5|Clomipramine-d3 hydrochloride
作者：德尔塔生物 日期：2025-06-09
生物活性：Clomipramine-d3 (hydrochloride) is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].分子量：354.33Formula：C19H21D3Cl2N2CAS 号：1398065-86-5非标记 CAS：17321-77-6性状：固体颜色：White to off-white中文名称：盐酸氯米帕明 d3 (盐酸盐)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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「同位素标记抑制剂」CAS:65854-97-9|Phenytoin-d10
作者：德尔塔生物 日期：2025-06-09
生物活性：Phenytoin-d10 is the deuterium labeled Phenytoin. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Phenytoin-d10 相关抗体:S100A10 Antibody (YA675)xCT Antibody (YA006)xCT Antibody (YA652)Alpha-ENaC AntibodyCRMP2 Antibody (YA3370)SLC12A1 Antibody (YA1403)CRMP1 Antibody (YA1941)CRMP5 Antibody (YA2497)CRMP3 Antibody (YA2563)CRMP4 Antibody (YA2777)分子量：262.33Formula：C15H2D10N2O2CAS 号：65854-97-9非标记 CAS：57-41-0性状：固体颜色：White to off-white中文名称：苯妥英 d10运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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