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Isovaleric acid-d7「同位素标记抑制剂」

Isovaleric acid-d7「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Isovaleric acid-d7 is the deuterium labeled Isovaleric acid[1]. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Isovaleric acid-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:109.17Formula:C5H3D7O2CAS 号:1219805-32-9性状:液体颜色:Colorless to light yellow运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

Sodium 3-Methyl-2-oxobutanoic acid-13C2「同位素标记抑制剂」

Sodium 3-Methyl-2-oxobutanoic acid-13C2「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:3-Methyl-2-oxobutanoic acid-13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sodium 3-Methyl-2-oxobutanoic acid-13C2 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:140.08Formula:C313C2H7NaO3CAS 号:634908-42-2非标记 CAS:3715-29-5性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资

Enoxacin-d8 hydrochloride,依诺沙星-d8「同位素标记抑制剂」

Enoxacin-d8 hydrochloride,依诺沙星-d8「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Enoxacin-d8 (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing[1][2][3][4].IC50 & Target:Quinolone体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Enoxacin-d8 hydrochloride 相关抗体:Ctip2 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyRPA32 Antibody (YA679)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyDrosha AntibodyHes1 AntibodyJunB AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNucleolin AntibodyPCNA AntibodyPDX1 AntibodyRbBP5 AntibodyS100A4 AntibodySP1 AntibodyBRCA1 Antibody (YA819)Argonaute 2 AntibodyBRCA1 AntibodyElongation Factor 1A1 AntibodyKAP1 AntibodyMCM2 Antibody (YA705)MLH1 Antibody (YA703)RNA Polymerase II Subunit B1 AntibodyRPA70 Antibody (YA678)MRP2 AntibodySP7/Osterix Antibody分

Moxifloxacin-d4,BAY 12-8039-d4 free base「同位素标记抑制剂」

Moxifloxacin-d4,BAY 12-8039-d4 free base「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Moxifloxacin-d4 is the deuterium labeled Moxifloxacin. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2].IC50 & Target:Quinolone体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Moxifloxacin-d4 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:405.46Formula:C21H20D4FN3O4CAS 号:2596386-23-9非标记 CAS:151096-09-2中文名称:莫西沙星 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substit

Hydralazine-d4 hydrochloride,盐酸肼屈嗪-d4「同位素标记抑制剂」

Hydralazine-d4 hydrochloride,盐酸肼屈嗪-d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Hydralazine-d4 hydrochloride is the deuterium labeled Hydralazine hydrochloride. Hydralazine hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Hydralazine-d4 hydrochloride 相关抗体:HIF1 alpha AntibodyHIF1 beta AntibodyHIF 2 alpha AntibodyCA9 Antibody (YA1368)HIF2 alpha Antibody (YA1445)ORP150 Antibody (YA1478)PHD3 Antibody (YA1612)CITED2 Antibody (YA2596)ORP1 Antibody (YA1477)HIF1AN Antibody (YA1907)OS9 Antibody (YA1939)PHD2 Antibody (YA2431)HIF Prolyl Hydroxylases Antibody (YA2975)HLF Antibody (YA2990)PHD1 Antibody (YA3325)分子量:200.66Formula:C8H5D4ClN4CAS 号:2749234-32-8非标记 CAS:304-20-1中文名称:盐酸肼屈嗪-d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Bourreli, B., et al., Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for s

GW2580-d6「同位素标记抑制剂」

GW2580-d6「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:GW2580-d6 is the deuterium labeled GW2580. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.GW2580-d6 相关抗体:M-CSF AntibodyCSF-1R Antibody (YA1299)G-CSF Antibody (YA3307)Destrin Antibody (YA1859)DCI Antibody (YA2658)DPS1 Antibody (YA2721)M-CSF Receptor Antibody (YA3205)G-CSF Receptor Antibody (YA3373)分子量:372.45Formula:C20H16D6N4O3CAS 号:2733770-48-2非标记 CAS:870483-87-7性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

Vapendavir-d5,BTA798-d5「同位素标记抑制剂」

Vapendavir-d5,BTA798-d5「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Vapendavir-d5 is the deuterium labeled Vapendavir. Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). Vapendavir (BTA798) possesses potent antiviral activity for enterovirus 71 (EV71) replication, with EC50 values of 0.5-1.4 μM in different EV71 strains[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:387.49Formula:C21H21D5N4O3CAS 号:2738376-73-1非标记 CAS:439085-51-5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Tijsma A, et al. The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2. [Content Brief][3]. Sun L, et al. Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5. [Content Brief]

(R-Praziquantel-d11,(R-吡喹酮 D11「同位素标记抑制剂」

(R-Praziquantel-d11,(R-吡喹酮 D11「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:(R)-Praziquantel-d11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].IC50 & Target[1]:5-HT2B ReceptorSchistosomeAntischistosomal体外研究(In Vitro):(R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(R)-Praziquantel-d11 相关抗体:MTNR1A Antibody分子量:323.47Formula:C19H13D11N2O2CAS 号:1399880-38-6非标记 CAS:57452-98-9性状:固体颜色:White to off-white中文名称:(R)-吡喹酮 d11运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: 99.57%参考文献[1]. Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8(1):1910. [Content Brief]

Hexadecanoate-13C16 potassium「同位素标记抑制剂」

Hexadecanoate-13C16 potassium「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Hexadecanoate-13C16 (potassium) is the 13C-labeled Hexadecanoate sodium. Hexadecanoate potassium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].分子量:310.40Formula:13C16H31KO2CAS 号:1458714-74-3性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Climbazole-d4,BAY-e 6975-d4「同位素标记抑制剂」

Climbazole-d4,BAY-e 6975-d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Climbazole-d4 is the deuterium labeled Climbazole. Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Climbazole-d4 相关抗体:SDHA Antibody分子量:296.79Formula:C15H13D4ClN2O2CAS 号:1185117-79-6非标记 CAS:38083-17-9性状:固体颜色:White to off-white中文名称:氯咪巴唑 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

Nadolol-d9,纳多洛尔 D9; SQ-11725-d9「同位素标记抑制剂」

Nadolol-d9,纳多洛尔 D9; SQ-11725-d9「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Nadolol-d9 is the deuterium labeled Nadolol. Nadolol is a non-selective and orally active β-adrenergic receptors blocker[1].分子量:318.46Formula:C17H18D9NO4CAS 号:94513-92-5非标记 CAS:42200-33-9性状:固体颜色:Off-white to light yellow中文名称:纳多洛尔 d9运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

Gliclazide-d4,格列齐特 d4「同位素标记抑制剂」

Gliclazide-d4,格列齐特 d4「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Gliclazide-d4 (S1702 D4) is the deuterium labeled Gliclazide. Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Gliclazide-d4 相关抗体:ATP1A1 AntibodyLGI1 Antibody (YA2885)Cardiac Troponin C Antibody (YA2125)Cardiac Troponin T Antibody (YA2719)SAP97 Antibody (YA2731)Kir2.1 Antibody (YA2871)分子量:327.44Formula:C15H17D4N3O3SCAS 号:1185039-30-8非标记 CAS:21187-98-4性状:固体颜色:White to off-white中文名称:格列齐特 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

Urapidil-d3,乌拉地尔 d3「同位素标记抑制剂」

Urapidil-d3,乌拉地尔 d3「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Urapidil-d3 is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Urapidil-d3 相关抗体:ADRB2 AntibodyMTNR1A AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量:390.49Formula:C20H26D3N5O3CAS 号:1398066-08-4非标记 CAS:34661-75-1性状:固体颜色:White to off-white中文名称:乌拉地尔 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

Probenecid-d14,丙磺舒 d14「同位素标记抑制剂」

Probenecid-d14,丙磺舒 d14「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Probenecid-d14 is the deuterium labeled Probenecid. Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Probenecid-d14 相关抗体:CD4 AntibodyMRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)TARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)TRPM8 Antibody (YA1609)TRPM7 Antibody (YA2391)SV40 T Antigen Antibody (YA3256)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)CLEC12A Antibody (YA1419)TrpC1 Antibody (YA1814)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)Tat SF1 Antibody (YA2886)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:299.45Formula:C13H5D14NO4SCAS 号:1189657-87-1非标记 CAS:57-66-9性状:固体颜色:White to off-white中文名称:丙磺舒 d14运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent

Clomipramine-d3 hydrochloride,Chlorimipramine-d3 (hydrochloride; G-34586-d3 (hydrochloride; NSC-169865-d3 (hydrochloride「同位素标记抑制剂」

Clomipramine-d3 hydrochloride,Chlorimipramine-d3 (hydrochloride; G-34586-d3 (hydrochloride; NSC-169865-d3 (hydrochloride「同位素标记抑制剂」

作者:德尔塔生物 日期:2025-08-13

生物活性:Clomipramine-d3 (hydrochloride) is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].分子量:354.33Formula:C19H21D3Cl2N2CAS 号:1398065-86-5非标记 CAS:17321-77-6性状:固体颜色:White to off-white中文名称:盐酸氯米帕明 d3 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)