-
CAS:1356841-27-4|Trandolaprilate-d5，Trandolaprilat d5; RU 44403 d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Trandolaprilate-d5 is a deuterium labeled Trandolaprilate (Trandolaprilat). Trandolaprilate is an angiotensin-converting enzyme (ACE) inhibitor[1].分子量：407.51Formula：C22H25D5N2O5CAS 号：1356841-27-4非标记 CAS：87679-71-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Shionoiri H, et al. Trandolaprilat, an angiotensin-converting enzyme inhibitor, is not excreted in bile via an ATP-dependent active transporter (cMOAT). Hypertens Res. 2001 May;24(3):235-40. [Content Brief]
-
CAS:1287040-94-1|Eletriptan-d3，UK-116044-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Eletriptan-d3 is the deuterium labeled Eletriptan hydrobromide. Eletriptan hydrobromide is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Eletriptan-d3 相关抗体:MTNR1A Antibody分子量：385.54Formula：C22H23D3N2O2SCAS 号：1287040-94-1非标记 CAS：143322-58-1运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Napier C, et al. Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors. Eur J Pharmacol, 1999, 368(2-3), 259-268. [Content Brief][3]. MaassenVanDenBrink A, et al. Craniovascular selectivity of eletriptan and sumatriptan in human isolated blood vessels. Neurology, 2000, 55(10), 1524-1530. [Content Brief][4]. Gupta P, et al. The in vivo pharmacological profile of eletriptan (UK-116,0
-
CAS:1329809-23-5|Dronedarone-d6 hydrochloride，决奈达隆 d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Dronedarone-d6 (hydrochloride) is the deuterium labeled Dronedarone. Dronedarone hydrochloride, a derivative of Amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone hydrochloride is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone hydrochloride is a substrate for and a moderate inhibitor of CYP3A4[1][2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dronedarone-d6 hydrochloride 相关抗体:Annexin VI AntibodyCytochrome C AntibodyxCT Antibody (YA006)Calbindin AntibodyCalreticulin AntibodyCytochrome P450 17A1 AntibodyxCT Antibody (YA652)Aromatase AntibodyADRB2 AntibodyCardiac Troponin I/TNNC1 AntibodyAlpha-ENaC AntibodyCYP11A1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Cytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Striatin 4 Antibody (YA2088)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Cytochrome P450 2E1 Antibody (YA2302)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody
-
CAS:1142095-93-9|Etravirine-d4，依曲韦林 D4; TMC-125 d4; R-165335 d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Etravirine-d4 is the deuterium labeled Etravirine. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.分子量：439.30Formula：C20H11D4BrN6OCAS 号：1142095-93-9非标记 CAS：269055-15-4性状：固体颜色：White to off-white中文名称：依曲韦林 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
-
CAS:121702-86-1|(R-(--Ibuprofen-d3，(R-Ibuprofen-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：(R)-(-)-Ibuprofen-d3 is the deuterium labeled (R)-(-)-Ibuprofen. (R)-(-)-Ibuprofen is the R enantiomer of Ibuprofen, inactive on COX, inhibits NF-κB activation; (R)-(-)-Ibuprofen exhibits anti-inflammatory and antinociceptive effects.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(R)-(-)-Ibuprofen-d3 相关抗体:NF-KB p65 AntibodyPhospho-NF-KB p65 (Ser536) AntibodyPhospho-NF-κB p65 (Ser529) AntibodyNF-KB p65 Antibody (YA267)NF-KB p105/p50 AntibodyRelB AntibodyRet AntibodyRetinoic Acid Receptor alpha AntibodySOD2 Antibody (YA071)SOX1 AntibodyTRAF2 AntibodyAnnexin A1 Antibody (YA832)DDX3 Antibody (YA784)NF-KB p100 AntibodyNF-KB p105 Antibody (YA700)Nrf1 AntibodyPhospho-NF-KB p65 (Thr254) AntibodySOD2 Antibody (YA670)TRAF6 AntibodyPhospho-NFKB1(Ser337) Antibody Nrf2 Antibody(YA895)DDIT3 AntibodyPhospho-NF-κB p65 (Ser536) Antibodyc-Rel AntibodyAnnexin A10 Antibody (YA1134)MYBBP1A Antibody (YA1387)Retinoic Acid Receptor beta Antibody (YA1574)Rel B Antibody (YA1852)Retinoic Acid Receptor gamma Antibody (YA1860)CARD11 Antibody (YA2615)分子量：209.30Formula：C13H15D3O2CAS 号：121702-86-1非标记 CAS：51146-57-7性状：固体颜色：White to off-white中文名称：(R)-(-)-布洛芬 d3运输条件：Room temperature in contine
-
CAS:1329643-44-8|(S-(+-Ibuprofen-d3，(S-Ibuprofen d3
作者：德尔塔生物 日期：2025-07-08
生物活性：(S)-(+)-Ibuprofen-d3 is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects[1][2].IC50 & Target：COX-12.1 μM (IC50)COX-21.6 μM (IC50)分子量：209.30Formula：C13H15D3O2CAS 号：1329643-44-8非标记 CAS：51146-56-6性状：固体颜色：White to off-white中文名称：(S)-(+)-布洛芬 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
-
CAS:1246818-63-2|Benzyl isothiocyanate-d7，苄基异硫氰酸酯 d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Benzyl isothiocyanate-d7 is the deuterium labeled Benzyl isothiocyanate. Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity[1][2]. Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Benzyl isothiocyanate-d7 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：156.26Formula：C8D7NSCAS 号：1246818-63-2非标记 CAS：622-78-6中文名称：苄基异硫氰酸酯 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommende
-
CAS:1185071-13-9|(Rac-5-Hydroxymethyl Tolterodine-d14，(Rac-Desfesoterodine-d14; (Rac-PNU-200577-d14
作者：德尔塔生物 日期：2025-07-08
生物活性：(Rac)-5-Hydroxymethyl Tolterodine-d14 is the deuterium labeled (Rac)-5-Hydroxymethyl Tolterodine. (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine can be used for overactive bladder research[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-5-Hydroxymethyl Tolterodine-d14 相关抗体:Muscarinic Acetylcholine receptor M3 AntibodyMuscarinic Acetylcholine Receptor M2 Antibody (YA2610)分子量：355.57Formula：C22H17D14NO2CAS 号：1185071-13-9非标记 CAS：200801-70-3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (537 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. L Nilvebrant, et al. Antimuscarinic potency and bladder selectivity of PNU-200577, a major metabolite of tolterodine. Pharmacol Toxicol. 1997 Oct;81(4
-
CAS:153698-86-3|Verlukast-d6，MK-679-d6; L 668019-d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Verlukast-d6 is a deuterium labeled Verlukast. Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma[1].IC50 & Target：leukotriene receptor[1]分子量：521.12Formula：C26H21D6ClN2O3S2CAS 号：153698-86-3非标记 CAS：120443-16-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Dahlén B, et al. Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. Thorax. 1993;48(12):1205-1210. [Content Brief]
-
CAS:1246812-30-5|(Rac-8-Hydroxy-efavirenz-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：rac 8-Hydroxy Efavirenz-d4 is the deuterium labeled rac 8-Hydroxy Efavirenz[1]. rac 8-Hydroxy Efavirenz-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：335.70Formula：C14H5D4ClF3NO3CAS 号：1246812-30-5非标记 CAS：205754-32-1性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
-
CAS:1279037-70-5|Scopolamine-d3 hydrobromide，Hyoscine-d3 hydrobromide
作者：德尔塔生物 日期：2025-07-08
生物活性：Scopolamine-d3 (hydrobromide) is the deuterium labeled Scopolamine hydrobromide[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：387.28Formula：C17H19D3BrNO4CAS 号：1279037-70-5非标记 CAS：6533-68-2性状：固体颜色：White to off-white中文名称：东莨菪碱氢溴酸盐 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)纯度 & 产品资料纯度： 98.01%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
-
CAS:93131-16-9|Cyclohexanecarboxylic acid-d11，环己烷羧酸-d11
作者：德尔塔生物 日期：2025-07-08
生物活性：Cyclohexanecarboxylic acid-d11 is the deuterium labeled Cyclohexanecarboxylic acid[1]. Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cyclohexanecarboxylic acid-d11 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：139.24Formula：C7HD11O2CAS 号：93131-16-9非标记 CAS：98-89-5性状：固体颜色：White to off-white中文名称：环己烷羧酸-d11运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
-
CAS:1331939-77-5|L-Ascorbic acid-13C6-1，L-抗坏血酸-13C6; L-Ascorbate-1; Vitamin C-13C6-1
作者：德尔塔生物 日期：2025-07-08
生物活性：L-Ascorbic acid-13C6-1 (L-Ascorbate-1; Vitamin C-13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166)[1]. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[2][3][4]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[5].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.L-Ascorbic acid-13C6-1 相关抗体:Annexin VI AntibodyBNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyMETTL3 Antibodyc-Myc AntibodyCyclin E1 AntibodyTSG101 AntibodyAIF Antibody (YA636)ALIX AntibodyAlkaline Phosphatase AntibodyCalbindin AntibodyCalnexin Antibody (YA573)Calreticulin AntibodyCatalase Antibody (YA552)Catalase Antibody (YA811)分子量：182.08Formula：13C6H8O6CAS 号：1331939-77-5非标记 CAS：50-81-7性状：固体颜色：White to off-white中文名称：L-抗坏血酸-13C6-1； 维生素C-13C6-1运输条件：Room t
-
CAS:1784060-40-7|6-Hydroxy Chlorzoxazone-15N,d2，6-羟基氯唑沙宗-15N,d2
作者：德尔塔生物 日期：2025-07-08
生物活性：6-Hydroxy Chlorzoxazone-15N,d2 is the 15N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221)[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.6-Hydroxy Chlorzoxazone-15N,d2 相关抗体:FMO3 Antibody (YA1992)分子量：188.57Formula：C7H2D2Cl15NO3CAS 号：1784060-40-7性状：固体颜色：White to off-white中文名称：6-羟基氯唑沙宗-15N,d2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
-
CAS:108395-15-9|2-Ketoglutaric acid-13C，α-酮戊二酸-13C; Alpha-Ketoglutaric acid-13C
作者：德尔塔生物 日期：2025-07-08
生物活性：2-Ketoglutaric acid-13C (Alpha-Ketoglutaric acid-13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636)[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2][3].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.2-Ketoglutaric acid-13C 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyMiTF AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)ZAP70 Antibody (YP4051)Asparagine Synthetase AntibodyCalnexin AntibodyCD3 epsilon AntibodyCD3D AntibodyKi67 Antibody (YA001)分子量：147.09Formula：C413CH6O5CAS 号：108395-15-9非标记 CAS：328-50-7性状：固体颜色：White to light yellow中文名称：α-酮戊二酸-13C运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 mont
咨询热线
18133906270
德尔塔官方微信