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「同位素标记抑制剂」4’-Hydroxyphenyl Carvedilol-d3
作者：德尔塔生物 日期：2025-06-13
生物活性：4’-Hydroxyphenyl Carvedilol-d3 is the deuterium labeled 4’-Hydroxyphenyl Carvedilol[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：425.49Formula：C24H23D3N2O5CAS 号：1189675-28-2非标记 CAS：142227-49-4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」rac Felodipine-(Methoxy-d3)
作者：德尔塔生物 日期：2025-06-13
生物活性：rac Felodipine-(Methoxy-d3) is the deuterium labeled rac Felodipine-(Methoxy)[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：387.27Formula：C18H16D3Cl2NO4CAS 号：1189970-31-7非标记 CAS：72509-76-3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Nefopam-d3 N-Oxide
作者：德尔塔生物 日期：2025-06-13
生物活性：Nefopam-d3 N-Oxide is the deuterium labeled Nefopam N-Oxide[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：272.36Formula：C17H16D3NO2CAS 号：1346603-50-6非标记 CAS：66091-32-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」(rac)-Mepindolol-d7
作者：德尔塔生物 日期：2025-06-13
生物活性：(rac)-Mepindolol-d7 is the deuterium labeled (rac)-Mepindolol[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：269.39Formula：C15H15D7N2O2CAS 号：1794970-97-0非标记 CAS：23694-81-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」4-Hydroxy Mepivacaine-d3
作者：德尔塔生物 日期：2025-06-13
生物活性：4-Hydroxy Mepivacaine-d3 is the deuterium labeled 4-Hydroxy Mepivacaine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：265.37Formula：C15H19D3N2O2CAS 号：1323251-06-4非标记 CAS：616-66-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Octhilinone-d17
作者：德尔塔生物 日期：2025-06-13
生物活性：Octhilinone-d17 is the deuterium labeled Octhilinone[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：230.44Formula：C11H2D17NOSCAS 号：1185109-79-8非标记 CAS：26530-20-1运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」iso-Nadolol (tert-Butyl-d9)
作者：德尔塔生物 日期：2025-06-13
生物活性：iso-Nadolol (tert-Butyl-d9) is the deuterium labeled iso-Nadolol (tert-Butyl)[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：318.46Formula：C17H18D9NO4CAS 号：1246820-10-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」Granisetron-d3
作者：德尔塔生物 日期：2025-06-13
生物活性：Granisetron-d3 is the deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy[1][2].细胞效力(Cellular Effect)HEK293Cell Line TypeValueDescriptionReferencesHEK293EC500.32 μMCompound: Granisetron, KutrilAgonist activity at human wild type 5-HT3A receptor expressed in HEK293 cells by FLIPR assayAgonist activity at human wild type 5-HT3A receptor expressed in HEK293 cells by FLIPR assay[PMID: 24128813]HEK293EC500.5 μMCompound: Granisetron, KutrilAgonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells by FLIPR assayAgonist activity at human wild type 5-HT3A/5-HT3B receptor expressed in HEK293 cells by FLIPR assay[PMID: 24128813]HEK293IC50311 μMCompound: granisetronInhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayInhibition of human MATE2K-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay[PMID: 23241029]HEK293IC504.3 μMCompound: granisetronInhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assayInhibition of human OCT2-mediated ASP+ uptake expressed in HEK293 cells after 3 mins by fluorescence assay[PMID: 23241029]HEK293IC505 μMCompound: granisetronInhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayInhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay[PMID: 23241029]体外研究(
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「同位素标记抑制剂」Homo Sildenafil-d5
作者：德尔塔生物 日期：2025-06-13
生物活性：Homo Sildenafil-d5 is the deuterium labeled Homo Sildenafil. Homo Sildenafil, an analog of Sildenafil, acts as a phosphodiesterase inhibitor[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Homo Sildenafil-d5 相关抗体:PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)PDE4D Antibody (YA1714)分子量：493.63Formula：C23H27D5N6O4SCAS 号：1216711-61-3非标记 CAS：642928-07-2中文名称：豪莫西地那非-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Jackie D Corbin, et al. Vardenafil: Structural Basis for Higher Potency Over Sildenafil in Inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochem Int. 2004 Nov;45(6):859-63. [Content Brief]
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「同位素标记抑制剂」Pimozide-d5 N-Oxide
作者：德尔塔生物 日期：2025-06-13
生物活性：Pimozide-d5 N-Oxide is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5[1][2].IC50 & Target：D1 ReceptorD3 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pimozide-d5 N-Oxide 相关抗体:FOXP3 Antibody (YA858)Phospho-STAT3 (Tyr705) Antibody (YA146)STAT3 Antibody (YA056)Phospho-STAT1 (Ser727) Antibody (YA148) Phospho-STAT1 (Tyr701) AntibodyPhospho-STAT3 (Tyr705) AntibodyFOXP3 AntibodyPhospho-STAT3 (Ser727) AntibodySTAT1 Antibody (YA059)STAT1 Antibody (YA667)STAT1 alpha AntibodySTAT2 Antibody (YA057)STAT5a AntibodySTAT5b AntibodySTAT6 AntibodyPhospho-STAT5 (Tyr694) Antibody (YA145)FOXP3 Antibody (YA759)Phospho-STAT1 (Ser727) Antibody (YA149) STAT3 Antibody (YA666)STAT4 AntibodySTAT5 AntibodyADRB2 AntibodyDRD2 AntibodyPhospho-STAT5(Tyr694) Antibody (YA1513)Dopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Salbutamol Antibody (YA901)Clenbuterol Antibody (YA904)T-bet / Tbx21 Antibody (YA1217)分子量：482.58Formula：C28H24
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「同位素标记抑制剂」CAS:1219798-43-2|Isonipecotic acid-d9
作者：德尔塔生物 日期：2025-06-13
生物活性：Isonipecotic acid-d9 is the deuterium labeled Isonipecotic acid[1]. Isonipecotic acid is a GABAA receptor partial agonist[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Isonipecotic acid-d9 相关抗体:GABARAP AntibodyIP3 Receptor Antibody (YA1596)GABA B Receptor 2 Antibody (YA1733)GABA B Receptor 1 Antibody (YA2418)GAD65 Antibody (YA758)GABA A Receptor alpha 1 Antibody (YA1315)GABA A Receptor beta 2 Antibody (YA1758)GABA Transporter 1 Antibody (YA1795)GAD67 Antibody (YA1807)ABAT Antibody (YA1964)GABA A Receptor alpha 5 Antibody (YA2249)GABA A Receptor beta 1 Antibody (YA2261)BGAT Antibody (YA2741)GABARAPL2 Antibody (YA2882)分子量：138.21Formula：C6H2D9NO2CAS 号：1219798-43-2中文名称：4-哌啶甲酸-d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Krehan D, et al. Phosphinic, phosphonic and seleninic acid bioisosteres of isonipecotic acid as novel and selective
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「同位素标记抑制剂」CAS:19031-56-2|Pimelic acid-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：Pimelic acid-d4 is the deuterium labeled Pimelic acid[1]. Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Pimelic acid-d4 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：164.19Formula：C7H8D4O4CAS 号：19031-56-2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharm
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「同位素标记抑制剂」CAS:1173022-88-2|Melamine-13C3
作者：德尔塔生物 日期：2025-06-13
生物活性：Melamine-13C3 is the 13C labeled Melamine[1]. Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：129.10Formula：13C3H6N6CAS 号：1173022-88-2非标记 CAS：108-78-1中文名称：三聚氰胺-13C3； 密胺-13C3； 蛋白精-13C3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Melamine
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「同位素标记抑制剂」CAS:646502-89-8|2-Fluorobenzoic acid-d4
作者：德尔塔生物 日期：2025-06-13
生物活性：2-Fluorobenzoic acid-d4 is the deuterium labeled 2-Fluorobenzoic acid[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：144.14Formula：C7HD4FO2CAS 号：646502-89-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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「同位素标记抑制剂」CAS:1219799-17-3|Cyclopropylmethyl bromide-d3
作者：德尔塔生物 日期：2025-06-13
生物活性：Cyclopropylmethyl bromide-d3 is the deuterium labeled Cyclopropylmethyl bromide[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：138.02Formula：C4H4D3BrCAS 号：1219799-17-3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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