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CAS:1329496-63-0|Maprotiline-d3 hydrochloride，盐酸马普替林-d3
作者：德尔塔生物 日期：2025-09-16
生物活性：Maprotiline-d3 (hydrochloride) is deuterium labeled Maprotiline (hydrochloride).体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Maprotiline-d3 hydrochloride 相关抗体:FOXO1A AntibodyBeclin 1 AntibodyAtg12 AntibodyATG5 AntibodyBmi1 AntibodyFOXO4 AntibodyFOXP3 AntibodyGABARAP AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyPhospho-FOXO3a(Ser253) AntibodyAPG5L AntibodyATG10 Antibody (YA603)ATG3 AntibodyATG4A AntibodyATG4C AntibodyATG7 AntibodyFOXO1 Antibody (YA430)FOXO3 AntibodyFOXP3 Antibody (YA759)FTO AntibodyPhospho-FOXO3A (Ser253) AntibodyFOXO1 AntibodyATG10 AntibodyGranulin Antibody (YA1162)ATG13 Antibody (YA1650)ATG9A Antibody (YA3081)LAMP2 Antibody (YA310)WIPI1 Antibody (YA1721)ATG16L1 Antibody (YA2187)分子量：316.88Formula：C20H21D3ClNCAS 号：1329496-63-0非标记 CAS：10347-81-6性状：固体颜色：White to off-white中文名称：盐酸马普替林-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1356383-38-4|Captopril-d3，卡托普利-d3; SQ 14225-d3
作者：德尔塔生物 日期：2025-09-16
生物活性：Captopril-d3 is deuterium labeled Captopril. Captopril (SQ 14225), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Captopril-d3 相关抗体:ACE2 AntibodyACE AntibodyACE Antibody (YA2094)分子量：220.30Formula：C9H12D3NO3SCAS 号：1356383-38-4非标记 CAS：62571-86-2中文名称：卡托普利-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268. [Content Brief][3]. Esmaeili S, et al. Captopril/enalapril inhibit promisc
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CAS:2702733-53-5|Azathioprine-d3，硫唑嘌呤-d3; BW 57-322-d3
作者：德尔塔生物 日期：2025-09-16
生物活性：Azathioprine-d3 (BW 57-322-d3) is the deuterium labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1].Clinical TrialNCT NumberSponsorConditionStart DatePhaseNCT01284725Assistance Publique Hopitaux De MarseilleNephritis of LupusJanuary 2011Phase 3NCT01802593Prof. Arie Levine|Wolfson Medical CenterCrohn´s DiseaseFebruary 2013Phase 4NCT00377637Hoffmann-La Roche|Aspreva PharmaceuticalsLupus NephritisJuly 2005Phase 3 NCT03393247Sixth Affiliated Hospital, Sun Yat-sen UniversityCrohn DiseaseJune 1, 2017Not ApplicableNCT03498703Ain Shams University|Capital Birth CenterRecurrent Implantation Failure|In Vitro Fertilization|Intracytoplsmic Sperm InjectionApril 25, 2018Phase 2NCT00987116Assistance Publique - Hôpitaux de ParisMyasthenia GravisJune 2009Phase 4NCT03930264Nova Laboratories Limited|Medicines Evaluation Unit Ltd|Syne Qua Non Limited|Alderley Analytical Ltd|Black County Pathology Services|Diamond Pharma Services Regulatory Affairs Consultancy|Boyd ConsultantsTherapeutic EquivalencyApril 11, 2019Phase 1NCT00976690Groupe d´Etude Therapeutique des Affections Inflammatoires DigestivesCrohn DiseaseOctober 2002Phase 3NCT01663623Human Genome Sciences Inc., a GSK Company|GlaxoSmithKlineVasculitisMarch 20, 2013Phase 3NCT02645565Jawaharlal Institute of Postgraduate Medical Education & ResearchLupus NephritisDecember 2015Phase 4NCT05813860Sixth Affiliated Hospital, Sun Yat-sen
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CAS:1432057-38-9|Ramelteon-d3，雷美替胺-d3; TAK-375-d3
作者：德尔塔生物 日期：2025-09-16
生物活性：Ramelteon-d3 is a deuterium-labelled Ramelteon (HY-A0014).分子量：262.36Formula：C16H18D3NO2CAS 号：1432057-38-9非标记 CAS：196597-26-9性状：固体颜色：White to off-white中文名称：雷美替胺-d3；瑞美替昂-d3；拉米替隆-d3；雷美尔通-d3；瑞美替胺-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1190043-13-0|Alosetron-d3，阿洛司琼-d3; GR 68755-d3; GR 68755X-d3
作者：德尔塔生物 日期：2025-09-16
生物活性：Alosetron-d3 is a deuterium labeled Alosetron. Alosetron is a serotonin 5HT3-receptor antagonist[1].分子量：297.37Formula：C17H15D3N4OCAS 号：1190043-13-0非标记 CAS：122852-42-0中文名称：阿洛司琼-d3；洛曲尼斯-d3；罗肠兴-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Harris LA, et al. Alosetron: an effective treatment for diarrhea-predominant irritable bowel syndrome. Womens Health (Lond). 2007 Jan;3(1):15-27. [Content Brief]
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CAS:2734919-98-1|Moxifloxacin-d3 hydrochloride，莫西沙星盐酸盐-d3; BAY 12-8039-d3
作者：德尔塔生物 日期：2025-09-16
生物活性：Moxifloxacin-d3 (hydrochloride) is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin hydrochloride is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2][3].IC50 & Target：Quinolone体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Moxifloxacin-d3 hydrochloride 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：440.91Formula：C21H22D3ClFN3O4CAS 号：2734919-98-1非标记 CAS：151096-09-2中文名称：盐酸莫西沙星-d3；莫西沙星盐酸盐-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (5
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CAS:1219804-76-8|Linuron-d6，利谷隆-d6
作者：德尔塔生物 日期：2025-09-16
生物活性：Linuron-d6 is the deuterium labeled 3-Bromo-L-tyrosine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Linuron-d6 相关抗体:Androgen receptor AntibodyPOMC Antibody (YA1619)分子量：255.13Formula：C9H4D6Cl2N2O2CAS 号：1219804-76-8非标记 CAS：330-55-2中文名称：利谷隆-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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CAS:2748492-38-6|Cyclobenzaprine-d6 hydrochloride，盐酸环苯扎林-d6; MK130-d6 hydrochloride
作者：德尔塔生物 日期：2025-09-16
生物活性：Cyclobenzaprine-d6 (hydrochloride) is deuterium labeled Cyclobenzaprine (hydrochloride).体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cyclobenzaprine-d6 hydrochloride 相关抗体:MTNR1A Antibody分子量：317.89Formula：C20H16D6ClNCAS 号：2748492-38-6非标记 CAS：6202-23-9中文名称：阿米替林EP杂质B-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kobayashi, H., Y. Hasegawa, and H. Ono, Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol, 1996. 311(1): p. 29-35. [Content Brief][3]. Honda, M., T. Nishida, and H. Ono, Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. Eur J Pharmacol, 2003. 458(1-2): p. 91-9. [Content Brief]
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CAS:1346601-02-2|Itopride-d6 hydrochloride，盐酸伊托必利-d6; HSR803-d6 hydrochloride
作者：德尔塔生物 日期：2025-09-16
生物活性：Itopride-d6 (hydrochloride) is deuterium labeled Itopride (hydrochloride). Itopride hydrochloride (HSR803), a gastroprokinetic Benzamide (HY-Z0283) derivative, is an inhibitor of acetylcholinesterase (AChE) and dopamine D2 receptor[1][2].IC50 & Target：D2 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Itopride-d6 hydrochloride 相关抗体:CHRNA9 AntibodyDRD2 AntibodyChAT AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：400.93Formula：C20H21D6ClN2O4CAS 号：1346601-02-2非标记 CAS：122892-31-3中文名称：盐酸伊托必利-d6；依托必利盐酸盐-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Hyun Chul Lim, et al. Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro. Effect of Itopride
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CAS:1089675-56-8|Phenylephrine-d6 hydrochloride，盐酸去氧肾上腺素-d6; (R-(--Phenylephrine-d6 hydrochloride; L-Phenylephrine-d6 hydrochloride
作者：德尔塔生物 日期：2025-09-16
生物活性：Phenylephrine-d6 (hydrochloride) is deuterium labeled Phenylephrine (hydrochloride). (R)-(-)-Phenylephrine hydrochloride is a selective α1-adrenoceptor agonist with pKis of 5.86, 4.87 and 4.70 for α1D, α1B and α1A receptors respectively.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Phenylephrine-d6 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：209.70Formula：C9H8D6ClNO2CAS 号：1089675-56-8非标记 CAS：61-76-7中文名称：盐酸去氧肾上腺素-d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 &
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CAS:1346604-21-4|Ulixacaltamide-d9 hydrochloride，Z944-d9 hydrochloride; PRAX-944-d9 hydrochloride
作者：德尔塔生物 日期：2025-09-16
生物活性：Ulixacaltamide-d9 (hydrochloride) salt is the deuterium labeled Ulixacaltamide hydrochloride[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ulixacaltamide-d9 hydrochloride 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)C10orf63 Antibody (YA2894)ITPK1 Antibody (YA3125)ORAI3 Antibody (YA3128)ORAI1 Antibody (YA3157)CREB Regulated Transcription Coactivator 2 Antibody (YA3279)分子量：429.40Formula：C19H19D9Cl2FN3O2CAS 号：1346604-21-4非标记 CAS：1199236-64-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of A
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CAS:1189693-23-9|Oxyphenbutazone-d9，羟布宗 d9
作者：德尔塔生物 日期：2025-09-16
生物活性：Oxyphenbutazone-d9 is the deuterium labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone.html" class="link-product" target="_blank">Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2][3].IC50 & Target：COX, Bacteria[2][3]体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Oxyphenbutazone-d9 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：333.43Formula：C19H11D9N2O3CAS 号：1189693-23-9非标记 CAS：129-20-4
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CAS:1189986-72-8|Diphenhydramine-d6 hydrochloride，盐酸苯海拉明 d6 (盐酸盐
作者：德尔塔生物 日期：2025-09-16
生物活性：Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].IC50 & Target：H1 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Diphenhydramine-d6 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyADGRE1 (F4/80) Antibody (YA002)TSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 Antibody分子量：297.85Formula：C17H16D6ClNOCAS 号：1189986-72-8非标记 CAS：147-24-0性状：固体颜色：White to off-white中文名称：盐酸苯海拉明 d6 (盐酸盐)运输条件：Room temperature in continental
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CAS:1020719-55-4|Paliperidone-d4，帕潘立酮 d4
作者：德尔塔生物 日期：2025-09-16
生物活性：Paliperidone-d4 is the deuterium labeled Paliperidone. Paliperidone (9-Hydroxyrisperidone), the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against schizophrenia[1].IC50 & Target：D2 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Paliperidone-d4 相关抗体:ADRB2 AntibodyDRD2 AntibodyMTNR1A AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Salbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：430.51Formula：C23H23D4FN4O3CAS 号：1020719-55-4非标记 CAS：144598-75-4性状：固体颜色：White to off-white中文名称：帕潘立酮 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (539 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitu
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CAS:1216429-25-2|AGN 193109-d7
作者：德尔塔生物 日期：2025-09-16
生物活性：AGN 193109-d7 is the deuterium labeled AGN 193109. AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs), with Kds of 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ, respectively.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.AGN 193109-d7 相关抗体:Retinoid X Receptor alpha Antibody分子量：399.53Formula：C28H17D7O2CAS 号：1216429-25-2非标记 CAS：171746-21-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Johnson AT, et al. Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors. J Med Chem. 1995 Nov 24;38(24):4764-7. [Content Brief][3]. Agarwal C, et al. AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells. J Biol Chem. 1996 May 24;271(21):12209-12. [Content Brief][4]. Standeven AM, et al. Specific antago
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