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Azido-PEG8-TFP ester，N3-PEG8-TFP ester|CAS:1818294-49-3
作者：德尔塔 日期：2022-08-31
中文：叠氮-八聚乙二醇-五氟苯酯英文：Azido-PEG8-TFP ester，N3-PEG8-TFP esterCAS：1818294-49-3产品参数1 Catalog #: Y-CL-0349 Name: N3-PEG8-TFP ester CAS: 1818294-49-3
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3-Azidopropionic Acid Sulfo-NHS Ester
作者：德尔塔 日期：2022-08-31
产品描述 3-Azidopropionic Acid Sulfo-NHS Ester is a water-soluble compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.分子量 314.20 分子式 C7H7N4NaO7S CAS No. 2055198-09-7存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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Azido-PEG12-t-butyl ester
作者：德尔塔 日期：2022-08-31
产品描述 Azido-PEG12-t-butyl ester is a PEG derivative containing an azide group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.分子量 699.84 分子式 C31H61N3O14 CAS No. 1818294-45-9存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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m-PEG12-azide
作者：德尔塔 日期：2022-08-31
产品描述 M-PEG12-azide is a PEG derivative containing an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with BCN, DBCO, alkyne via Click Chemistry to yield a stable triazole linkage.分子量 585.69 分子式 C25H51N3O12 CAS No. 89485-61-0存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度 DMSO: Soluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
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Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA
作者：德尔塔 日期：2022-08-31
产品描述 Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double claevable 3-unit and 4-unit PEG linker for antibody-drug-conjugation (ADC). 靶点活性 Cleavable分子量 1346.57 分子式 C66H99N13O17 CAS No. T17676存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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N-DBCO-N-bis(PEG2-C2-NHS ester)
作者：德尔塔 日期：2022-08-31
产品描述 N-DBCO-N-bis(PEG2-C2-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 818.82 分子式 C41H46N4O14 CAS No. 2128735-29-3存储
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N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
作者：德尔塔 日期：2022-08-31
产品描述 N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 1087.78 分子式 C63H79ClN4O10 CAS No. 2107273-76-5存储
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N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
作者：德尔塔 日期：2022-08-31
产品描述 N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 1095.26 分子式 C54H74N6O16S CAS No. 2353409-72-8存储
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N-DBCO-N-bis(PEG2-C2-acid)
作者：德尔塔 日期：2022-08-31
产品描述 N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 624.68 分子式 C33H40N2O10 CAS No. 2110449-00-6存储
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DBCO-PEG4-VC-PAB-DMEA-PNU-159682
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker DBCO-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1]. 靶点活性 Duocarmycins分子量 1695.81 分子式 C86H106N10O26 CAS No. 2259318-56-2存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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DBCO-NH-PEG7-C2-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NH-PEG7-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 781.85 分子式 C40H51N3O13 CAS No. T17756存储
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DBCO-(PEG2-Val-Cit-PAB)2
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs). 靶点活性 Cleavable分子量 1347.56 分子式 C69H94N12O16 CAS No. T17788存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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DBCO-(PEG2-VC-PAB-MMAE)2
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-(PEG2-VC-PAB-MMAE)2 is made by MMAE conjugated to the cleavable DBCO-(PEG2-VC-PAB)2 linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate[1]. 靶点活性 Auristatin分子量 2835.5 分子式 C149H224N22O32 CAS No. 2259318-55-1存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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DBCO-NHCO-S-S-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NHCO-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 565.66 分子式 C28H27N3O6S2 CAS No. T17774存储 Powder: -20°C for 3 years In solvent:
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DBCO-CONH-S-S-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 565.66 分子式 C28H27N3O6S2 CAS No. 1435934-53-4存储 Powder: -20°C for 3 years In solv
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