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DBCO-Sulfo-NHS ester sodium
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.分子量 532.5 分子式 C25H21N2NaO8S CAS No. 1400191-52-7存储 Powder: -20°C for 3 years In sol
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DBCO-NH-(CH2)4COOH
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-NH-(CH2)4COOH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 Alkyl-Chain 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 404.46 分子式 C24H24N2O4 CAS No. 2375193-74-9存储
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DBCO-NHCO-PEG2-CH2COOH
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-NHCO-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 464.51 分子式 C26H28N2O6 CAS No. T17765存储
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DBCO-PEG4-Ahx-DM1
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. 靶点活性 Maytansinoids分子量 1297.92 分子式 C68H89ClN6O17 CAS No. T17793存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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DOTA-PEG5-C4-DBCO
作者:德尔塔 日期:2022-08-31
产品描述 DOTA-PEG5-C4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 982.13 分子式 C49H71N7O14 CAS No. T17845存储
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DBCO-mPEG (MW 5kDa)
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-mPEG (MW 5kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 N/A CAS No. T17753存储 Powder: -20°C for 3 years In solvent: -80°C for 2 year
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DBCO-mPEG (MW 30kDa)
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-mPEG (MW 30kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 N/A CAS No. T17752存储 Powder: -20°C for 3 years In solvent: -80°C for 2 yea
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DBCO-mPEG (MW 2kDa)
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-mPEG (MW 2kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 N/A CAS No. T17751存储 Powder: -20°C for 3 years In solvent: -80°C for 2 year
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DBCO-mPEG (MW 20kDa)
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-mPEG (MW 20kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 N/A CAS No. T17750存储 Powder: -20°C for 3 years In solvent: -80°C for 2 yea
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DBCO-mPEG (MW 10kDa)
作者:德尔塔 日期:2022-08-31
产品描述 DBCO-mPEG (MW 10kDa) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 N/A CAS No. T17749存储 Powder: -20°C for 3 years In solvent: -80°C for 2 yea
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DBCO-C3-PEG4-amine
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-C3-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs Alkyl/ether 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 609.71 分子式 C33H43N3O8 CAS No. T177
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DBCO-C2-PEG4-amine
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-C2-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs Alkyl/ether 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 595.68 分子式 C32H41N3O8 CAS No. T177
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DBCO-PEG4-C2-acid
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 552.62 分子式 C30H36N2O8 CAS No. 1537170-85-6存储
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PC DBCO-PEG3-biotin
作者:德尔塔 日期:2022-08-30
产品描述 PC DBCO-PEG3-biotin is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 1002.14 分子式 C50H63N7O13S CAS No. T18521存储 Powder: -20°C for 3 years In so
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Diazo Biotin-PEG3-DBCO
作者:德尔塔 日期:2022-08-30
产品描述 Diazo Biotin-PEG3-DBCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 973.15 分子式 C52H60N8O9S CAS No. T17822存储 Powder: -20°C for 3 years In s