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利哌酮

发布时间:2022-01-14     作者:德尔塔   分享到:

【产品介绍】:

Risperidone is a benzisoxazole derivative. It functions as an antagonist for dopamine D2, histamine H1 and α1 and α2 adrenergic receptors. Risperidone is used to treat schizophrenia, bipolar disorder and autismRisperidone has been used:• to study its effects on bone formation and differentiation• to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients• to reverse induced schizophrenia-like behavior in mice 安全信息 标识符号 GHS06 信号词 Danger 危害声明 H301 警示性声明 P301+P310 RTECS UV1164800 WGK 3 属性 产品名称 利哌酮 产品名称 Risperidone 别名 利培酮;瑞司哌酮 英文别名 Risperdal; Risperidal; Risperdal Consta; Rispolept; Risperin; Rispolin; Sequinan; Risperdal M-Tab;3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl)ethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one CAS编号 106266-06-2 分子式 C23H27FN4O2 分子量 410.48 PubChem CID 5073 MDL号 MFCD00274576 UN Number 2811 Reaxys-RN 4891881 Merck Index 8233 Class 6.1 Packing group III 规格或纯度 ≥98% 应用 Risperidone has been used: · to study its effects on bone formation and differentiation · to investigate the relationship between risperidone (RIS) dosages and RIS plasma levels in autism spectrum disorder (ASD) pediatric patients · to reverse induced schizophrenia-like behavior in mice 备注 如果有可能,您尽量在同一天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 生化机理 Risperidone is an antipsychotic; serotonin-dopamine antagonist.Atypical antipsychotic agent. Potent 5-HT 2A antagonist (K i = 0.4 nM). Also displays high affinity at D 2 receptors (K i = 3.13 nM). 熔点 172 °C 溶解性 Soluble in DMSO (10 mM), ethanol (10 mM), chloroform, and methanol. Insoluble in water. 储存温度 2-8°C储存 运输条件 冰袋运输 Blessing WW et al.  et al (2017) Clozapine, chlorpromazine and risperidone dose-dependently reduce emotional hyperthermia, a biological marker of salience. Psychopharmacology (Berl)(Berl) 3259-3269 PMID:28812124