阿托伐醌
【产品介绍】:
Atovaquone 用于**或预防肺孢子菌肺炎,弓形虫病, 疟疾和巴贝西虫。 安全信息 RTECS QJ5616500 WGK 3 属性 产品名称 阿托伐醌 产品名称 Atovaquone 别名 阿托伐醌 英文别名 Mepron;trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione CAS编号 95233-18-4 分子式 C22H19ClO3 分子量 366.84 PubChem CID 74989 MDL号 MFCD00889188 Merck Index 866 规格或纯度 ≥98% 应用 Atovaquone may be used as a pharmaceutical secondary reference standard for the determination of the analyte in plasma samples by liquid-liquid extraction followed by reversed-phase high-performance liquid chromatography with ultraviolet detection. These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. 备注 如果有可能,您尽量在同一天配置溶液,并在当天使用完它。但是,如果您需要预先配制储备溶液,我们建议您将溶液等份保存在-20°C的密封小瓶中。通常,它们最多可以使用一个月。在使用前和打开样品瓶之前,我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度,用法和处理的建议吗?请访问我们的常见问题(FAQ)页面以获取更多详细信息。 生化机理 Atovaquone is an anti-protozoal mitochondrial electron transport inhibitor; Antimalarial; Antipneumocystic, and has also been used to treat toxoplasmosis. It is an analog of protozoan mitochondrial protein ubiquinone, and acts by inhibiting the cytochrome bc(1) complex via interactions with the Rieske iron-sulfur protein and cytochrome b in the ubiquinol oxidation pocket.Antiparasitic agent. Protozoan ubiquinone analog. Inhibits coenzyme Q-complex III binding at the Qo cytochrome domain. Disrupts the protozoa electron transport chain. Active against Plasmodium spp., P. carinii, Babesia spp., and Toxoplasma go 熔点 223 °C 敏感性 对热敏感 储存温度 -20°C储存 运输条件 超低温冰袋运输