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阿齐沙坦

发布时间:2022-01-14     作者:德尔塔   分享到:

【产品介绍】:

安全信息 WGK 3 属性 产品名称 阿齐沙坦 产品名称 Azilsartan 别名 阿齐沙坦 英文别名 1-[[2′-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl) [1,1′-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid;2-Ethoxy-1-{[2′-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid; TAK-536 CAS编号 147403-03-0 分子式 C25H20N4O5 分子量 456.45 PubChem CID 135415867 MDL号 MFCD00916395 规格或纯度 ≥99% 备注 10mg、50mg卖完停产,不再备货 生化机理 Azilsartan is a highly potent and slowly dissociating Angiotensin II type 1 (AT1) receptor blocker (ARB) with an IC50 of 2.6 nM. It is the active form of Azilsartan medoxomil, used for treatment of hypertension. Azilsartan may also have potentially beneficial effects on metabolic syndrome including insulin sensitizing activity that may involve more than just blockade of AT(1) receptors. 熔点 188 °C(dec.) 敏感性 对热敏感 溶解性 DMSO: soluble15 mg/mL 储存温度 2-8°C储存 运输条件 冰袋运输