【产品介绍】：

安全信息 RTECS MC0814400 属性 产品名称 Noopept 产品名称 Noopept 别名 N-(1-(苯基乙酰基)-L-脯氨酰)甘氨酸乙酯 英文别名 1-(2-Phenylacetyl)-L-prolyl-glycine ethyl ester；GVS 111；N-Phenylacetyl-L-prolylglycine ethyl ester；SGS 111；Ethyl N-[1-(Phenylacetyl)-L-prolyl]glycinate CAS编号 157115-85-0 分子式 C17H22N2O4 分子量 318.37 PubChem CID 180496 MDL号 MFCD00941121 规格或纯度 ≥98% 备注 有关更多信息，请参考SDS。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 生化机理 Description:IC50 Value: N/ANoopept (GVS-111) is a medication promoted and prescribed in Russia and neighbouring countries as a nootropic.in vitro: Nooglutil exhibits pharmacologically significant competition with a selective agonist of AMPA receptors ([G-3H]Ro 48-8587) for the receptor binding sites (with IC50 = 6.4 +/- 0.2 microM), while the competition of noopept for these receptor binding sites was lower by an order of magnitude (IC50 = 80 +/- 5.6 microM) [1]. GVS-111 significantly increased neuronal survival after H(2)O(2)-treatment displaying a dose-dependent neuroprotective activity from 10 nM to 100 microM, and an IC(50) value of 1.21+/-0.07 microM. GVS-111 inhibited the accumulation of intracellular free radicals and lipid peroxidation damage in neurons treated with H(2)O(2) or FeSO(4), sμggesting an antioxidant mechanism of action [2].in vivo: N-Phenylacetyl-L-prolylglycine ethyl ester (GVS-111) administered intravenously at a dose of 0.Novel, proline-containing, nootropic and neuroprotective dipeptide drug. Modulates physiological functions such as cognition and anxiety. α-synuclein amyloid toxicity rescued in cell models. Stimulates\xa0NGF and BDNF expression in rat hippocampus. 熔点 96 °C 比旋光度 -116° (C=0.4,CHCl3) 敏感性 对热敏感 溶解性 solubility in DMSO:20 mg/mL, clear 储存温度 -20°C储存 运输条件 超低温冰袋运输