【产品介绍】：

Pidotimod是一种合成的二肽分子，对适应性和先天性免疫反应都有生物学免疫活性。对动物和人的样本进行体外研究发现Pidotimod对适应性和先天性免疫反应都有很好的活性，这一结论也在体内实验中得到了确认。这些活性已经应用到临床，在减轻儿童上呼吸道和尿道感染复发率上效果良好。在成人呼吸道感染复发的抑制上也有同样效果A synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses. 属性 产品名称 匹多莫德 产品名称 Pidotimod 别名 匹多莫德; 匹多替莫 英文别名 (R)-3-[[(S)-5-Oxo-2-pyrrolidinyl]carbonyl]-1,3-thiazolidine-4-carboxylic Acid ;(4R)-3-{[(2S)-5-oxopyrrolidin-2-yl]carbonyl}-1,3-thiazolidine-4-carboxylic acid CAS编号 121808-62-6 分子式 C9H12N2O4S 分子量 244.27 PubChem CID 65944 MDL号 MFCD00867583 Merck Index 7419 规格或纯度 ≥98% 应用 A synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses. 备注 如果有可能，您尽量在同一天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。 生化机理 Pidotimod is a synthetic dipeptide with immunological modulatory activity on both the adaptive and innate immune responses. This compound has been shown to induce dendritic cell maturation and up-regulate the expression of HLA-DR and co-stimulatory molecules CD83 and CD86, which are integral to communication with adaptive immunity cells. Pidotimod has also been shown to stimulate dendritic cells to release pro-inflammatory molecules such as MCP-1 and TNF-α cytokines, and to inhibit thymocyte apoptosis caused by a variety of apoptosis inducing molecules.Immunostimulant. Active in adaptive and innate immune responses in vitro and in vivo . Shows adjuvant effects in vivo . Stimulates the release of pro-inflammatory factors from dendritic cells. Orally active. 熔点 196-198°C 比旋光度 -136° (C=2,5mol/L HCl) 溶解性 Soluble in water (37.8 g/L), methanol (13.8 g/L), ethanol (4.4 g/L), and DMF (72.4 g/L). 储存温度 2-8°C储存 运输条件 冰袋运输