CAS号:515846-21-6|SP-4206
【产品介绍】:
中文别名 5-[[2,3-dichloro-4-[5-[1-[2-[[(2R)-2-(diaminomethylideneamino)-4-methylpentanoyl]amino]acetyl]piperidin-4-yl]-1-methylpyrazol-3-yl]phenoxy]methyl]furan-2-carboxylic acid 英文别名 SP-4206; SP 4206; SP4206. CAS号 515846-21-6 SMILES O=C(C1=CC=C(COC2=CC=C(C3=NN(C)C(C4CCN(C(CNC([C@H](/N=C(N)\N)CC(C)C)=O)=O)CC4)=C3)C(Cl)=C2Cl)O1)O Inchi InChI=1S/C30H37Cl2N7O6/c1-16(2)12-21(36-30(33)34)28(41)35-14-25(40)39-10-8-17(9-11-39)22-13-20(37-38(22)3)19-5-7-23(27(32)26(19)31)44-15-18-4-6-24(45-18)29(42)43/h4-7,13,16-17,21H,8-12,14-15H2,1-3H3,(H,35,41)(H,42,43)(H4,33,34,36)/t21-/m1/s1 InchiKey VNZHOIDQBPFEJU-OAQYLSRUSA-N 分子式 Formula C30H37Cl2N7O6 分子量 Molecular Weight 662.57 闪点 FP 熔点 Melting point 沸点 Boiling point Polarizability极化度 密度 Density 蒸汽压 Vapor Pressure 溶解度Solubility 性状 Solid powder 储藏条件 Storage conditions Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). 产品说明 SP-4206(CAS:515846-21-6 ):仅限应用于工业或者科学研究过程中非医疗目的,不应用于人类或动物的临床诊断以及治过程疗,该产品非药用,非食用。 IntroductionSP-4206 is a IL-2Ralpha inhibitor. SP4206 (Kd approximately 70 nM) was found to block binding of the IL-2alpha receptor (IL-2Ralpha) to IL-2 (Kd approximately 10 nM). Mutational studies show that SP4206 targets virtually the same critical "hot-spot" residues on IL-2 that drive binding of IL-2Ralpha. Moreover, a mutation that enhances binding to the IL-2Ralpha near these hot spots also enhances binding to SP4206. Application1 Application2 Application3 警示图 危险性 Warning 危险性警示 安全声明 安全防护 备注 对不起,暂无产品评价!