CAS:458-37-7|姜黄素
【产品介绍】:
产品名称 姜黄素 英文名称 Curcumin 应用 酸碱指示剂,pH7.8(黄)~9.2(红棕)。显色反应测铍、锆和镁,硼酸盐和试剂。 一种天然酚性物质,抗肿瘤和消炎物质,并具有抗氧化特性,能诱导癌细胞凋亡。 Curcumin has been used: · to measure its antibacterial activity in vitro · to determine its preventative effects for Alzheimer′s disease (AD) in mice · as a bifunctional agent for generation and validation of the erythroid 2-related factor 2 (Nrf2) reporter system · to study its in vitro inhibitory effects on human liver glucuronidation activity · to evaluate the effects of curcumin on Parkinson′s disease (PD)-like phenotypes 规格或纯度 ≥65% 别名 克扣明;川芎内酯 B 英文别名 Natural Yellow 3;Diferuloylmethane;Diferulylmethane;(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione 运输条件 超低温冰袋运输 生化机理 A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity.1 Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.Flavonoid derived from Curcuma longa plant. Potent antioxidant, anti-inflammatory, analgesic and anticancer agent. Lipooxygenase and cyclooxygenase inhibitor (IC 50 values are 8 and 52 μM, respectively). Blood-brain barrier permeable.CAS编号 458-37-7 熔点 183°C 溶解性 Soluble in acetone, dimethylsufoxide, ethanol and dimethyl formamide. Insoluble in water. 储存温度 -20°C储存 RTECS MI5230000 MDL号 MFCD00008365 密度 0.93 分子量 368.38 分子式 C21H20O6 EC号 207-280-5 PubChem CID 587790