【产品介绍】：

生物活性：Nifuroxazide-d4 is the deuterium labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Nifuroxazide-d4 相关抗体:
FOXP3 Antibody (YA858)
Phospho-STAT3 (Tyr705) Antibody (YA146)
STAT3 Antibody (YA056)
Phospho-STAT1 (Ser727) Antibody (YA148)
Phospho-STAT1 (Tyr701) Antibody
Phospho-STAT3 (Tyr705) Antibody
FOXP3 Antibody
Phospho-STAT3 (Ser727) Antibody
STAT1 Antibody (YA059)
STAT1 Antibody (YA667)
STAT1 alpha Antibody
STAT2 Antibody (YA057)
STAT5a Antibody
STAT5b Antibody
STAT6 Antibody
Phospho-STAT5 (Tyr694) Antibody (YA145)
FOXP3 Antibody (YA759)
Phospho-STAT1 (Ser727) Antibody (YA149)
STAT3 Antibody (YA666)
STAT4 Antibody
STAT5 Antibody
MRP2 Antibody
Elongation factor 2 Antibody (YA962)
Elongation factor 2 Antibody (YA964)
PU.1/SPI1 Antibody (YA1116)
Phospho-STAT5(Tyr694) Antibody (YA1513)
Sulfadimidine Antibody (YA906)
Elongation factor 2 Antibody (YA963)
Anthrax Protective gen Antibody (YA1060)
T-bet / Tbx21 Antibody (YA1217)
分子量：279.24
Formula：C12H5D4N3O5
CAS 号：1188487-83-3
非标记 CAS：965-52-6
中文名称：硝呋齐特 d4
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (524 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
 [Content Brief]
[2]. Nelson EA, et al. Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. Blood. 2008 Dec 15;112(13):5095-102.
 [Content Brief]
[3]. Zhu Y, et al. Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma. Sci Rep. 2016 Feb 2;6:20253.
 [Content Brief]