【产品介绍】：

生物活性：Artesunate-d3 is the deuterium labeled Artesunate. Artesunate is an inhibitor of both STAT-3 and exported protein 1 (EXP1).
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Artesunate-d3 相关抗体:
FOXP3 Antibody (YA858)
S100A10 Antibody (YA675)
Ferritin Heavy Chain Antibody
Phospho-STAT3 (Tyr705) Antibody (YA146)
STAT3 Antibody (YA056)
Phospho-STAT1 (Ser727) Antibody (YA148)
Phospho-STAT1 (Tyr701) Antibody
Phospho-STAT3 (Tyr705) Antibody
FOXP3 Antibody
Phospho-STAT3 (Ser727) Antibody
STAT1 Antibody (YA059)
STAT1 Antibody (YA667)
STAT1 alpha Antibody
STAT2 Antibody (YA057)
STAT5a Antibody
STAT5b Antibody
STAT6 Antibody
Phospho-STAT5 (Tyr694) Antibody (YA145)
FOXP3 Antibody (YA759)
AMID/FSP1 Antibody
Peroxiredoxin 1 Antibody (YA692)
Phospho-STAT1 (Ser727) Antibody (YA149)
STAT3 Antibody (YA666)
STAT4 Antibody
STAT5 Antibody
PRDX3 Antibody (YA909)
Phospho-STAT5(Tyr694) Antibody (YA1513)
Ferritin Light Chain Antibody (YA971)
Ferritin Light Chain Antibody (YA972)
T-bet / Tbx21 Antibody (YA1217)
分子量：387.44
Formula：C19H25D3O8
CAS 号：1316303-44-2
非标记 CAS：88495-63-0
中文名称：青蒿酯 d3
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (531 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
 [Content Brief]
[2]. Ilamathi M, et al. Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma. Curr Top Med Chem. 2016;16(22):2453-63.
 [Content Brief]
[3]. Lisewski AM, et al. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 2014 Aug 14;158(4):916-928.
 [Content Brief]
[4]. Wang B, et al. Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51. Cancer Biol Ther. 2015;16(10):1548-56.
 [Content Brief]