【产品介绍】：

生物活性：ABT 737-d8 is the deuterium labeled ABT-737. ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research[1][2][3].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
ABT-737-d8 相关抗体:
Mouse IgG Isotype Control
6X His-tag (C-terminal) Antibody (YA860)
DYKDDDDK Tag (FLAG) Antibody
GFP Antibody
Myc-tag Antibody
HA tag Antibody (YA856)
GST-Tag Antibody HRP Conjugated
V5-tag Antibody
Collagen I alpha 2 Antibody
Rabbit IgG Isotype Control
6X His Tag (C-terminal) Antibody
His Tag Antibody (HRP) (YA877)
HA Tag Antibody (HRP) (YA876)
EYFP Tag Antibody (YA872)
HSV Tag Antibody (YA878)
MBP Tag Antibody (YA879)
RFP Tag Antibody (YA882)
S Tag Antibody (YA883)
SRT Tag Antibody (YA884)
Strep-Tag II Antibody (YA885)
TAP Tag Antibody (YA887)
Collagen II Antibody
Collagen III Antibody
Collagen X Antibody
Collagen IV Antibody
Collagen I Antibody
Collagen VI alpha 1/2/3 Antibody (YA2637)
AmCyan Tag Antibody (YA864)
DsbA Tag Antibody (YA868)
E2 Tag Antibody (YA870)
分子量：821.48
Formula：C42H37D8ClN6O5S2
CAS 号：1217686-68-4
非标记 CAS：852808-04-9
性状：固体
颜色：Light yellow to yellow
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Powder：-20°C：3 years，4°C：2 years
In solvent：-80°C：6 months，-20°C：1 month