【产品介绍】：

生物活性：Trimetazidine-d8 (dihydrochloride) is the deuterium labeled Trimetazidine dihydrochloride. Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor[1][2][3][4].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Trimetazidine-d8 dihydrochloride 相关抗体:
FOXO1A Antibody
Beclin 1 Antibody
Atg12 Antibody
ATG5 Antibody
Bmi1 Antibody
FOXO4 Antibody
FOXP3 Antibody
GABARAP Antibody
LAMP2 Antibody (YA713)
LAMP2a Antibody
Phospho-FOXO3a(Ser253) Antibody
APG5L Antibody
ATG10 Antibody (YA603)
ATG3 Antibody
ATG4A Antibody
ATG4C Antibody
ATG7 Antibody
FOXO1 Antibody (YA430)
FOXO3 Antibody
FOXP3 Antibody (YA759)
FTO Antibody
Phospho-FOXO3A (Ser253) Antibody
FOXO1 Antibody
ATG10 Antibody
Granulin Antibody (YA1162)
ATG13 Antibody (YA1650)
ATG9A Antibody (YA3081)
LAMP2 Antibody (YA310)
WIPI1 Antibody (YA1721)
ATG16L1 Antibody (YA2187)
分子量：347.31
Formula：C14H16D8Cl2N2O3
CAS 号：1219795-37-5
非标记 CAS：13171-25-0
性状：固体
颜色：White to off-white
中文名称：盐酸曲美他嗪 d8 (双盐酸盐)
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)