【产品介绍】：

生物活性：Fenvalerate-d5 is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Fenvalerate-d5 相关抗体:
PFKFB3 Antibody
DUSP1 Antibody
DUSP3 Antibody
MRP2 Antibody
Elongation factor 2 Antibody (YA962)
Elongation factor 2 Antibody (YA964)
PU.1/SPI1 Antibody (YA1116)
Intestinal Alkaline Phosphatase Antibody (YA1559)
PFKL Antibody (YA1597)
SHP2 Antibody (YA1643)
PP1C alpha/beta Antibody (YA1700)
PTP1B Antibody (YA1776)
PLEKHA1 Antibody (YA2145)
PGAM1 Antibody (YA2156)
DUSP6 Antibody (YA2280)
PRAS40 Antibody (YA3179)
PPP4C Antibody (YA687)
Sulfadimidine Antibody (YA906)
Elongation factor 2 Antibody (YA963)
Phospho-PTP1B (Ser352) Antibody (YA1027)
Phospho-PTP1B (Ser378) Antibody (YA1028)
Placental Alkaline Phosphatase Antibody (YA1038)
Placental Alkaline Phosphatase Antibody (YA1039)
PP1C alpha Antibody (YA1040)
PP1C alpha Antibody (YA1041)
SHP1 Antibody (YA1044)
SHP1 Antibody (YA1045)
Anthrax Protective gen Antibody (YA1060)
PP1C gamma Antibody (YA1068)
PPP5C Antibody (YA1069)
分子量：424.93
Formula：C25H17D5ClNO3
CAS 号：1246815-00-8
非标记 CAS：51630-58-1
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (531 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. E Enan, et al. Specific Inhibition of Calcineurin by Type II Synthetic Pyrethroid Insecticides. Biochem Pharmacol. 1992 Apr 15;43(8):1777-84.;A R Reilein, et al. Regulation of Organelle Movement in Melanophores by Protein Kinase A (PKA), Protein Kinase C
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