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「同位素标记抑制剂」Procaine-d4 hydrochloride

发布时间:2025-06-12     作者:德尔塔生物   分享到:

【产品介绍】:

生物活性:Procaine-d4 (hydrochloride) is the deuterium labeled Procaine hydrochloride. Procaine hydrochloride is a DNA-demethylating agent. Procaine hydrochloride acts through multiple targets and has a slow onset and a short duration of action[1][2].
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Procaine-d4 hydrochloride 相关抗体:
Ctip2 Antibody
Rb Antibody
Phospho-Rb (Ser807) Antibody
RPA32 Antibody (YA679)
CDT1 Antibody
DNA-PKcs/PRKDC Antibody
Hes1 Antibody
JunB Antibody
LIN28A Antibody
Lin28B Antibody
MCM2 Antibody
Nanog Antibody
Nucleolin Antibody
PCNA Antibody
PDX1 Antibody
RbBP5 Antibody
S100A4 Antibody
SP1 Antibody
BRCA1 Antibody (YA819)
C/EBP Beta Antibody
Argonaute 2 Antibody
BRCA1 Antibody
Elongation Factor 1A1 Antibody
KAP1 Antibody
KDM1A Antibody (YA718)
MCM2 Antibody (YA705)
MLH1 Antibody (YA703)
RNA Polymerase II Subunit B1 Antibody
RPA70 Antibody (YA678)
SP7/Osterix Antibody
分子量:276.80
Formula:C13H17D4ClN2O2
非标记 CAS:51-05-8
中文名称:盐酸普鲁卡因 d4 (盐酸盐)
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (526 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33(12): p. 1573-9.
 [Content Brief]
[3]. Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63(16): p. 4984-9.
 [Content Brief]
[4]. Adamec, R.E. and C. Stark-Adamec, The effects of procaine HCl on population cellular and evoked response activity within the limbic system of the cat. Evidence for differential excitatory action of procaine in a variety of limbic circuits. Prog Neuropsych
 [Content Brief]