【产品介绍】：

生物活性：Propiconazole-d7 is the deuterium labeled Propiconazole. Propiconazole is a broad-spectrum triazole fungicide that inhibits the conversion of lanosterol to ergosterol, leading to fungal cell membrane disruption. Propiconazole inhibits S. cerevisiae, but not rat liver, microsomal cytochrome P450 (IC50s=0.04 and >200 µM, respectively). Propiconazole inhibits the growth of T. deformans and R. stolonifer (ED50s=0.073 and 4.6 µg/mL, respectively). Propiconazole increases production of reactive oxygen species (ROS)[1].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Propiconazole-d7 相关抗体:
Catalase Antibody (YA552)
Catalase Antibody (YA811)
SDHA Antibody
C Reactive Protein Antibody (YA941)
PARK7/DJ1 Antibody (YA1799)
C Reactive Protein Antibody (YA939)
C Reactive Protein Antibody (YA940)
PON1 Antibody (YA1666)
PON2 Antibody (YA1688)
分子量：349.26
Formula：C15H10D7Cl2N3O2
CAS 号：1246818-14-3
非标记 CAS：60207-90-1
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (547 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
 [Content Brief]
[2]. Teng M, et al. Effect of Propiconazole on the Lipid Metabolism of Zebrafish Embryos ( Danio rerio). J Agric Food Chem. 2019;67(16):4623-4631.
 [Content Brief]