【产品介绍】：

生物活性：Thiabendazole-13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Thiabendazole-13C6 相关抗体:
Parkin Antibody
MCU Antibody
Mitofusin 2 Antibody
LIAS Antibody
NDUFS8 Antibody (YA1352)
TOMM20 Antibody (YA1380)
NUDT9 Antibody (YA1453)
CPS1 Antibody (YA1661)
Complex III Subunit 5 Antibody (YA1865)
NDUFB8 Antibody (YA1947)
MFF Antibody (YA2012)
NDUFS4 Antibody (YA2072)
MT ND1 Antibody (YA2089)
Mitochondrial Fission 1 Protein Antibody (YA2098)
Cyclophilin 40 Antibody (YA2099)
TIMM44 Antibody (YA2207)
NDUFS1 Antibody (YA2535)
CLPX Antibody (YA2814)
MTCO2 Antibody (YA3254)
Mitochondrial Ferritin Antibody (YA3353)
mtTFA Antibody (YA3360)
Mitofusin 1 Antibody
Ornithine Carbamoyltransferase/OTC Antibody (YA1230)
NDUFB10 Antibody (YA1330)
NDUFB11 Antibody (YA1331)
NDUFB2 Antibody (YA1335)
NDUFB4 Antibody (YA1338)
NDUFB9 Antibody (YA1340)
NDUFC2 Antibody (YA1343)
NDUFS3 Antibody (YA1346)
分子量：207.20
Formula：C413C6H7N3S
CAS 号：2140327-29-1
非标记 CAS：148-79-8
中文名称：噻菌灵-13C6； 噻苯唑-13C6； 噻苯咪唑-13C6
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (527 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]
[2]. Cha, H.J., et al., Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol, 2012. 10(8): p. e1001379.
 [Content Brief]
[3]. Zhang, J., et al., Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie, 2013. 68(12): p. 962-8.
 [Content Brief]