德尔塔
您当前所在位置:首页 > 分析科学 > 新品上市

「同位素标记抑制剂」(R)-Verapamil-d7 hydrochloride

发布时间:2025-06-10     作者:德尔塔生物   分享到:

【产品介绍】:

生物活性:(R)-Verapamil-d7 (hydrochloride) is a deuterium labeled (R)-Verapamil hydrochloride. (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents[1][2].
分子量:498.11
Formula:C27H32D7ClN2O4
非标记 CAS:38176-02-2
中文名称:盐酸维拉帕米杂质22-d7
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (526 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Plumb JA, et al. The activity of verapamil as a resistance modifier in vitro in drug resistant human tumour cell lines is not stereospecific. Biochem Pharmacol. 1990 Feb 15;39(4):787-92.
 [Content Brief]
[2]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22.
 [Content Brief]