「同位素标记抑制剂」Neo Spiramycin I-dC
【产品介绍】:
生物活性:Neo Spiramycin I-d3 is the deuterium labeled Neo Spiramycin I (HY-143623)[1]. Neo Spiramycin I (NSPI) is the active metabolite of Spiramycin (SPI) with antimicrobial activity. Neo Spiramycin is widely used in veterinary medicine[2].
体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量:701.90
Formula:C36H59D3N2O11
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (537 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[Content Brief]
[2]. Saleh H, et al. Validation of hplc-uv multi-residue method for the simultaneous determination of tetracycline, oxytetracycline, spiramycin and neospiramycin in raw milk[J]. Food Analytical Methods, 2021, 14: 36-43.