【产品介绍】：

生物活性：Prilocaine-d7 (hydrochloride) is deuterium labeled Prilocaine (hydrochloride). Prilocaine hydrochloride, an amino amide, is a Na, K-ATPase inhibitor. Prilocaine has neurotoxic effects[1][2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Prilocaine-d7 hydrochloride 相关抗体:
ATP7B Antibody (YA2029)
ATP1B1 Antibody (YA2084)
ATP6V1A Antibody (YA2211)
ATPB Antibody (YA2214)
ATP5F1A Antibody (YA2306)
ATP1A2 Antibody (YA2934)
ATP1B3 Antibody (YA2201)
ATP5G Antibody (YA2205)
ATP6V0D1 Antibody (YA2208)
ATP1A3 Antibody (YA2462)
ATP4B Antibody (YA2972)
分子量：263.81
Formula：C13H14D7ClN2O
非标记 CAS：1786-81-8
性状：固体
颜色：White to off-white
中文名称：盐酸丙胺卡因-d7
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：4°C, sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
纯度 & 产品资料
纯度： 98.16%
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
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[2]. M Mete, et al. Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line. Biotech Histochem. 2015 Apr;90(3):216-22.
 [Content Brief]
[3]. H Kutchai, et al. Effects of local anaesthetics on the activity of the Na,K-ATPase of canine renal medulla. Pharmacol Res. 2000 Jan;41(1):1-7.
 [Content Brief]