「同位素标记抑制剂」CAS:478511-06-7|Thymidine-13C
【产品介绍】:
生物活性:Thymidine-13C is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]
体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
Thymidine-13C 相关抗体:
BNSP Antibody
FACL4 Antibody
BrdU Antibody (YA578)
GAPDH Antibody
Glucose 6 Phosphate Dehydrogenase Antibody
Ctip2 Antibody
METTL3 Antibody
Rb Antibody
Phospho-Rb (Ser807) Antibody
TSG101 Antibody
RPA32 Antibody (YA679)
Alkaline Phosphatase Antibody
Calnexin Antibody (YA573)
CDT1 Antibody
DNA-PKcs/PRKDC Antibody
Hes1 Antibody
JunB Antibody
Lamin A/C Antibody
Lamin B1 Antibody
LAMP1 Antibody
LAMP2 Antibody (YA713)
LAMP2a Antibody
LIN28A Antibody
Lin28B Antibody
MCM2 Antibody
Nanog Antibody
NQO1 Antibody (YA697)
NQO1 Antibody (YA261)
Nucleolin Antibody
OPA1 Antibody
分子量:243.22
Formula:C913CH14N2O5
CAS 号:478511-06-7
非标记 CAS:50-89-5
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (531 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
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[2]. Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17).;FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4
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