「同位素标记抑制剂」CAS:1399880-38-6|(R)-Praziquantel-d11
【产品介绍】:
生物活性:(R)-Praziquantel-d11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].
IC50 & Target[1]:5-HT2B Receptor
Schistosome
Antischistosomal
体外研究(In Vitro):(R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite[1].
德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.
(R)-Praziquantel-d11 相关抗体:
MTNR1A Antibody
分子量:323.47
Formula:C19H13D11N2O2
CAS 号:1399880-38-6
非标记 CAS:57452-98-9
性状:固体
颜色:White to off-white
中文名称:(R)-吡喹酮 d11
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:Powder:-20°C:3 years,4°C:2 years
In solvent:-80°C:6 months,-20°C:1 month
纯度 & 产品资料
纯度: 99.57%
参考文献
[1]. Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8(1):1910.
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