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「同位素标记抑制剂」Almorexant (αS,1S) isomer-13C,d3

「同位素标记抑制剂」Almorexant (αS,1S) isomer-13C,d3

作者:德尔塔生物 日期:2025-06-10

生物活性:Almorexant (αS,1S) isomer-13C,d3 is the 13C- and deuterium labeled Almorexant (αS,1S) isomer[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[19].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:516.57Formula:C2813CH28D3F3N2O3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

「同位素标记抑制剂」N-Nitroso-Acebutolol-d7

「同位素标记抑制剂」N-Nitroso-Acebutolol-d7

作者:德尔塔生物 日期:2025-06-10

生物活性:N-Nitroso-Acebutolol-d7 is the deuterium labeled N-Nitroso-Acebutolol[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:372.47Formula:C18H20D7N3O5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (516 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

「同位素标记抑制剂」Aripiprazole metabolite-d6

「同位素标记抑制剂」Aripiprazole metabolite-d6

作者:德尔塔生物 日期:2025-06-10

生物活性:Aripiprazole metabolite-d6 is the deuterium labeled Aripiprazole metabolite[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:255.30Formula:C13H9D6NO4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (517 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

「同位素标记抑制剂」N-Desmethyl Azelastine-d4-1

「同位素标记抑制剂」N-Desmethyl Azelastine-d4-1

作者:德尔塔生物 日期:2025-06-10

生物活性:N-Desmethyl Azelastine-d4-1 is the deuterium labeled N-Desmethyl Azelastine[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:371.90Formula:C21H18D4ClN3O运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

「同位素标记抑制剂」Elagolix-13C,d3 sodium

「同位素标记抑制剂」Elagolix-13C,d3 sodium

作者:德尔塔生物 日期:2025-06-10

生物活性:Elagolix-13C,d3 (sodium) is the 13C- and deuterium labeled Elagolix sodium. Elagolix sodium is a human GnRH receptor (GnRHR) antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[56].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Elagolix-13C,d3 sodium 相关抗体:Prolactin Receptor Antibody (YA2411)Prolactin Antibody (YA1586)GCDFP 15 Antibody (YA2242)分子量:657.58Formula:C3113CH26D3F5N3NaO5非标记 CAS:832720-36-2中文名称:恶拉戈利钠杂质27-13C,d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief][2]. Kim SM, et al. Discovery of an Orally Bioavailable Gonadotropin-Releasing Hormone Receptor Antagonist. J Med Chem. 2016 Oct 13;59(19):9150-9172. Epub 2016 Sep 27. [Content Brief][3]. Chen C, et al. Discovery of sodium R-(+)-4-{2-[5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}buty

「同位素标记抑制剂」Dienogest-d5

「同位素标记抑制剂」Dienogest-d5

作者:德尔塔生物 日期:2025-06-10

生物活性:Dienogest-d5 is deuterium labeled Dienogest.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dienogest-d5 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量:316.45Formula:C20H20D5NO2非标记 CAS:65928-58-7中文名称:地诺孕素-d5;双烯孕腈-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Oettel M, et al. Effect of ethinyl e

「同位素标记抑制剂」Docetaxel-d5 trihydrate

「同位素标记抑制剂」Docetaxel-d5 trihydrate

作者:德尔塔生物 日期:2025-06-10

生物活性:Docetaxel-d5 (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Docetaxel-d5 trihydrate 相关抗体:ERK1/2 Antibodyalpha Tubulin AntibodyLC3A/B AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C AntibodyBeta Tubulin Antibodyc-Myc AntibodyCyclin E1 Antibodybeta Tubulin Antibody (YA839)AIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)Doublecortin AntibodyDR5 AntibodyDrosha Antibody分子量:866.96Formula:C43H54D5NO17非标记 CAS:148408-66-6中文名称:多西他赛巴豆醛类似物-d5运输条件:Room temperatur

「同位素标记抑制剂」Solifenacin-d5 succinate

「同位素标记抑制剂」Solifenacin-d5 succinate

作者:德尔塔生物 日期:2025-06-10

生物活性:Solifenacin-d5 (succinate) is deuterium labeled Solifenacin (Succinate). Solifenacin Succinate (YM905) is a novel muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively.IC50 & Target:mAChR2mAChR1mAChR3体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Solifenacin-d5 succinate 相关抗体:Muscarinic Acetylcholine receptor M3 AntibodyMuscarinic Acetylcholine Receptor M2 Antibody (YA2610)分子量:485.58Formula:C27H27D5N2O6非标记 CAS:242478-38-2中文名称:索非那新琥珀酸盐-d5;琥珀酸素立芬新-d5;琥珀酸索非那新-d5;琥珀酸索菲那新-d5;琥珀酸索利那新-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Krishna SR, Rao BM, Rao NS.A validated rapid stability-indicating method for the determination of related substances in solifenacin succinate by ultra-fast liquid chromatography.J Chromatogr Sci. 2010 Nov;48(10):807-10. [Content Brief

「同位素标记抑制剂」Erdosteine-13C4

「同位素标记抑制剂」Erdosteine-13C4

作者:德尔塔生物 日期:2025-06-10

生物活性:Erdosteine-13C4 is a 13C-labeled Erdosteine. Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation[1][2]. Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects[3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Erdosteine-13C4 相关抗体:NF-KB p65 AntibodyPhospho-NF-KB p65 (Ser536) AntibodyPhospho-NF-κB p65 (Ser529) AntibodyNF-KB p65 Antibody (YA267)NF-KB p105/p50 AntibodyRelB AntibodyRet AntibodyRetinoic Acid Receptor alpha AntibodySOD2 Antibody (YA071)SOX1 AntibodyTRAF2 AntibodyAnnexin A1 Antibody (YA832)DDX3 Antibody (YA784)NF-KB p100 AntibodyNF-KB p105 Antibody (YA700)Nrf1 AntibodyPhospho-NF-KB p65 (Thr254) AntibodySOD2 Antibody (YA670)TRAF6 AntibodyPhospho-NFKB1(Ser337) Antibody Nrf2 Antibody(YA895)MRP2 AntibodyDDIT3 AntibodyPhospho-NF-κB p65 (Ser536) AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)c-Rel AntibodySulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)分子量:253.28Formula:C413C4H11NO4S2非标记 CAS:84611-23-4中文名称:厄多司坦 13C4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended condi

「同位素标记抑制剂」Amlodipine-d4 besylate

「同位素标记抑制剂」Amlodipine-d4 besylate

作者:德尔塔生物 日期:2025-06-10

生物活性:Amlodipine-d4 (besylate) is the deuterium labeled Amlodipine besylate. Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for the research of high blood pressure and cancer[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Amlodipine-d4 besylate 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)C10orf63 Antibody (YA2894)ITPK1 Antibody (YA3125)ORAI3 Antibody (YA3128)ORAI1 Antibody

「同位素标记抑制剂」Chlortetracycline-d6 hydrochloride

「同位素标记抑制剂」Chlortetracycline-d6 hydrochloride

作者:德尔塔生物 日期:2025-06-10

生物活性:Chlortetracycline-d6 (hydrochloride) is the deuterium labeled Chlortetracycline hydrochloride. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic, inhibits binding of aminoacyl-tRNA to ribosomes.IC50 & Target:Tetracycline体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Chlortetracycline-d6 hydrochloride 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:521.38Formula:C22H18D6Cl2N2O8非标记 CAS:64-72-2中文名称:盐酸金霉素 d6 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuteri

「同位素标记抑制剂」Mecillinam-d12

「同位素标记抑制剂」Mecillinam-d12

作者:德尔塔生物 日期:2025-06-10

生物活性:Mecillinam-d12 is deuterium labeled Mecillinam. Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms[1].IC50 & Target:β-lactam体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Mecillinam-d12 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:337.50Formula:C15H11D12N3O3S非标记 CAS:32887-01-7运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. M E Olson, et al. Amdinocillin Trea

「同位素标记抑制剂」Abiraterone acetate-d4

「同位素标记抑制剂」Abiraterone acetate-d4

作者:德尔塔生物 日期:2025-06-10

生物活性:Abiraterone acetate-d4 is the deuterium labeled Abiraterone acetate. Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a proagent form of Abiraterone (CB7598).体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Abiraterone acetate-d4 相关抗体:Cytochrome C AntibodyCytochrome P450 17A1 AntibodyAromatase AntibodyCYP11A1 AntibodyCytochrome P450 1B1 Antibody (YA1836)Adrenodoxin Antibody (YA2005)Cytochrome P450 27A1 Antibody (YA2163)Cytochrome P450 2C9 Antibody (YA2166)Cytochrome P450 2E1 Antibody (YA2302)Cytochrome P450 Reductase Antibody (YA2619)Thromboxane A Synthase Antibody (YA2670)Cytochrome P450 3A4 Antibody (YA3365)HSD11B1 Antibody (YA3376)Cytochrome P450 17A1 Antibody (YA786)CYP2E1 AntibodyCYP1A2 AntibodyPLSCR3 Antibody (YA1672)PROX1 Antibody (YA1754)Cytochrome P450 4A Antibody (YA2087)Cytochrome P450 24A1 Antibody (YA2121)Cytochrome P450 26A1 Antibody (YA2259)COX5B Antibody (YA2550)Steroidogenic Factor 1 Antibody (YA3166)Dynein Light Chain Tctex Type 1 Antibody (YA3263)Cytochrome P450 2D6 Antibody (YA3384)分子量:395.57Formula:C26H29D4NO2非标记 CAS:154229-18-2中文名称:乙酸阿比特龙酯 d4运输条件:

「同位素标记抑制剂」Rifampicin-d8

「同位素标记抑制剂」Rifampicin-d8

作者:德尔塔生物 日期:2025-06-10

生物活性:Rifampicin-d8 (Rifampin-d8) is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Rifampicin-d8 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Poliovirus Receptor Antibody (YA2556)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量:830.99Formula:C43H50D8N4O12非标记 CAS:13292-46-1中文名称:利福平-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (532 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216

「同位素标记抑制剂」Didanosine-d2

「同位素标记抑制剂」Didanosine-d2

作者:德尔塔生物 日期:2025-06-10

生物活性:Didanosine-d2 is the deuterium labeled Didanosine. Didanosine (Videx) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Didanosine-d2 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:238.24Formula:C10H10D2N4O3非标记 CAS:69655-05-6中文名称:去羟肌苷 d2运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Knupp, C.A., et al., Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex. Clin Pharmacol Ther, 1991. 49(5): p. 523-35. [Content Brief][3]. Bissuel, F., et al., Fulminant hepatitis with severe lactate acidosis in HIV-infected patients on didanosine therapy. J Intern Med, 1994. 235(4): p. 367-71. [Content Brief]