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CAS:1255644-45-1|3-Methylglutaconic acid-13C3，β-Methylglutaconic acid-13C3
作者：德尔塔生物 日期：2025-07-08
生物活性：3-Methylglutaconic acid-13C3 is the 13C labeled 3-Methylglutaconic acid[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：147.10Formula：C313C3H8O4CAS 号：1255644-45-1非标记 CAS：5746-90-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
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CAS:1451194-68-5|N-Linolenoylethanolamine-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：N-Linolenoylethanolamine-d4 is the deuterium labeled N-Linolenoylethanolamine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：325.52Formula：C20H31D4NO2CAS 号：1451194-68-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (512 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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CAS:2070015-14-2|Atovaquone-d4，阿托伐醌D4
作者：德尔塔生物 日期：2025-07-08
生物活性：Atovaquone-d4 is the deuterium labeled Atovaquone. Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia[1].IC50 & Target：Plasmodium分子量：370.86Formula：C22H15D4ClO3CAS 号：2070015-14-2非标记 CAS：95233-18-4性状：固体颜色：Light yellow to yellow中文名称：阿托伐醌 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 99.8%参考文献[1]. Looareesuwan, S., et al., Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand. Am J Trop Med Hyg, 1996. 54(1): p. 62-6. [Content Brief]
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CAS:2512224-37-0|Raloxifene-d10-1，Keoxifene-d10; LY156758(free base-d10; LY139481-d10
作者：德尔塔生物 日期：2025-07-08
生物活性：Raloxifene-d10-1 is the deuterium labeled Raloxifene[1]. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Raloxifene-d10-1 相关抗体:Estrogen Receptor alpha Antibody (YA768)Estrogen Receptor alpha AntibodyGPR30 AntibodyPBR Antibody (YA1785)REA Antibody (YA1848)Estrogen Related Receptor gamma Antibody (YA2009)ERR alpha Antibody (YA2283)Estrogen Receptor beta Antibody (YA1892)14-3-3 Antibody (YA1949)Estrogen Inducible Protein pS2 Antibody (YA2377)MVK Antibody (YA3093)分子量：483.64Formula：C28H17D10NO4SCAS 号：2512224-37-0非标记 CAS：84449-90-1运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (533 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief
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CAS:2673270-28-3|TML-6-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：TML-6-d3 is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.TML-6-d3 相关抗体:PGK1 AntibodyNF-KB p65 AntibodyPhospho-NF-KB p65 (Ser536) AntibodyPhospho-NF-κB p65 (Ser529) AntibodyNF-KB p65 Antibody (YA267)Keap1 AntibodyPhospho-mTOR (Ser2448) Antibody (YA171)Phospho-Nrf2 (Ser40) Antibody (YA169)mTOR Antibody (YA281)NF-KB p105/p50 AntibodyRelB AntibodyRet AntibodyRetinoic Acid Receptor alpha AntibodyRHEB AntibodySOD2 Antibody (YA071)SOX1 AntibodyTRAF2 AntibodyPhospho-mTOR (Ser2448) Antibody (YA691)Phospho-Nrf2 (Ser40) Antibody (YA168)Hamartin Antibody4E BP1 AntibodyAnnexin A1 Antibody (YA832)DDX3 Antibody (YA784)mTOR AntibodyNF-KB p100 AntibodyNF-KB p105 Antibody (YA700)Nrf1 AntibodyPhospho-4E BP1 (Thr46) AntibodyPhospho-mTOR (Ser2481) AntibodyPhospho-NF-KB p65 (Thr254) Antibody分子量：526.64Formula：C30H34D3NO7CAS 号：2673270-28-3非标记 CAS：1462868-88-7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under
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CAS:2673270-14-7|Mitotane-d8，米托坦-d8; 2,4′-DDD-d8; o,p'-DDD-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Mitotane-d8 is the deuterium labeled Mitotane[1]. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Mitotane-d8 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase Antib
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CAS:2315262-31-6|Psychosine-d7，Galactosylsphingosine-d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Psychosine-d7 is deuterium labeled Psychosine. Psychosine, a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Psychosine-d7 相关抗体:Phospho-PKC alpha (T638) AntibodyPhospho-PKC zeta (T560) AntibodyPKC alpha AntibodyPKC beta 1 AntibodyPKC beta 2 AntibodyPKC delta AntibodyPKC epsilon AntibodyPKC gamma AntibodyEzrin Antibody (YA767)PKC eta AntibodySGK1 Antibody (YA1525)PKC theta Antibody (YA3162)Villin AntibodyPhospho-PKC alpha (Ser657) Antibody (YA1023)Phospho-PKC alpha (Thr638) Antibody (YA1024)PRKCQ Antibody (YA1106)AMHR2 Antibody (YA1337)Phospho-PKC (Ser660) Antibody (YA1394)Phospho-PKC delta (Ser299) Antibody (YA2628)Phospho-PKC zeta/lambda (Thr410/Thr412) Antibody (YA2631)Phospho-PKC zeta (Thr560) Antibody (YA2679)分子量：468.68Formula：C24H40D7NO7CAS 号：2315262-31-6非标记 CAS：2238-90-6中文名称：鞘氨醇半乳糖苷-d7；半乳糖基鞘氨醇-d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 &
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CAS:1219798-52-3|Terbuthylazine-desethyl-d9，Desethylterbuthylazine-d9
作者：德尔塔生物 日期：2025-07-08
生物活性：Terbuthylazine-desethyl-d9 is the deuterium labeled Terbuthylazine-desethyl[1]. Terbuthylazine-desethyl (Desethylterbuthylazine) is a chloro dealkylated metabolite of Terbuthylazine (a triazine herbicide)[2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：210.71Formula：C7H3D9ClN5CAS 号：1219798-52-3非标记 CAS：30125-63-4中文名称：去乙基特丁津-d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Potter TL, et, al. Tillage, cover-crop residue management, and irrigation incorporation impact on fomesafen runoff. J Agric Food Chem. 2011 Jul 27;59(14):7910-5. [Content Brief][3]. Navarro S, et, al. Determination of simazine, terbuthylazine, and their dealkylated chlorotriazine metabolites in soil using sonication microextraction and gas chromatography. J AOAC Int. Sep-Oct 200083(5):1239-43. [Content Brief]
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CAS:1131342-85-2|Finasteride-d9，非那雄胺-d9; MK-906-d9
作者：德尔塔生物 日期：2025-07-08
生物活性：Finasteride-d9 is deuterium labeled Finasteride. Finasteride (MK-906) is a potent and competitive 5α-reductase inhibitor, with an IC50 of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：381.60Formula：C23H27D9N2O2CAS 号：1131342-85-2非标记 CAS：98319-26-7性状：固体颜色：White to off-white中文名称：非那雄胺-d9；非那斯特萊-d9；非那司提-d9；非那甾胺-d9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 99.13%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Flores E, et, al. Steroid 5alpha-reductase inhibitors. Mini Rev Med Chem. 2003 May;3(3):225-37. [Content Brief][3]. Yun DK, et, al. Finasteride Increases the Expression of Hemoxygenase-1 (HO-1) and NF-E2-Related Factor-2 (Nrf2) Proteins in PC-3 Cells: Implic
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CAS:265989-50-2|Ortho-hydroxy atorvastatin lactone-d5，正羟基阿托伐他汀内酯杂质93-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Ortho-hydroxy atorvastatin lactone-d5 is deuterium labeled 2-Hydroxy atorvastatin lactone. 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ortho-hydroxy atorvastatin lactone-d5 相关抗体:FMO3 Antibody (YA1992)分子量：561.65Formula：C33H28D5FN2O5CAS 号：265989-50-2非标记 CAS：163217-74-1中文名称：正羟基阿托伐他汀内酯杂质93-d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (536 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Guo CX, et al. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica. 2012;42(8):784‐790. [Content Brief][3]. Turner NA, et al. Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferatio
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CAS:202114-53-2|Fmoc-leucine-13C，Fmoc-L-亮氨酸-13C
作者：德尔塔生物 日期：2025-07-08
生物活性：Fmoc-leucine-13C is a 13C-labeled Boc-Glycine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fmoc-leucine-13C 相关抗体:PPAR alpha AntibodyPPAR gamma AntibodyPPAR gamma Antibody (YA122)PGC1 beta Antibody (YA1411)分子量：354.40Formula：C2013CH23NO4CAS 号：202114-53-2非标记 CAS：35661-60-0中文名称：Fmoc-L-亮氨酸-13C运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (520 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
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CAS:2300178-70-3|Toxoflavin-13C4
作者：德尔塔生物 日期：2025-07-08
生物活性：Toxoflavin-13C4 is the 13C-labeled Toxoflavin. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2]. Antibiotic properties.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Toxoflavin-13C4 相关抗体:Beta-Catenin AntibodyTCF7L2/TCF4 AntibodyMRP2 Antibodybeta Catenin Antibody (YA936)beta Catenin Antibody (YA938)Elongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)Phospho-delta 1 Catenin (Ser268) Antibody (YA1019)PU.1/SPI1 Antibody (YA1116)Phospho-beta Catenin (Ser33/Ser37) Antibody (YA3096)gamma Catenin AntibodySulfadimidine Antibody (YA906)beta Catenin Antibody (YA937)Elongation factor 2 Antibody (YA963)Phospho-delta 1 Catenin (Tyr228) Antibody (YA1018)Phospho-delta 1 Catenin (Thr916) Antibody (YA1020)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：196.13Formula：C313C4H6N5O2CAS 号：2300178-70-3非标记 CAS：84-82-2运输条件：Ro
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CAS:1173021-09-4|Clenproperol-d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Clenproperol-d7 is the deuterium labeled Clenproperol. Clenproperol is a β2-adrenergic agonist[1].IC50 & Target：β adrenergic receptor分子量：270.21Formula：C11H9D7Cl2N2OCAS 号：1173021-09-4非标记 CAS：38339-11-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. González-Antuña A, et al. Simultaneous determination of seven β2-agonists in human and bovine urine by isotope dilution liquid chromatography-tandem mass spectrometry using compound-specific minimally 13C-labelled analogues. J Chromatogr A. 2014;1372C:63-71. [Content Brief]
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CAS:2749328-53-6|Dehydroaripiprazole-d8，OPC-14857-d8; DM-14857-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Dehydroaripiprazole-d8 is deuterium labeled Dehydroaripiprazole. Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole. Dehydroaripiprazole has with antipsychotic activity equivalent to Aripiprazole[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dehydroaripiprazole-d8 相关抗体:MTNR1A Antibody分子量：454.42Formula：C23H17D8Cl2N3O2CAS 号：2749328-53-6非标记 CAS：129722-25-4中文名称：阿立哌唑EP杂质E-d8 (Dehydro Aripiprazole)运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (527 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Kirschbaum KM, et al. Serum levels of aripiprazole and dehydroaripiprazole, clinical response and side effects. World J Biol Psychiatry. 2008;9(3):212-8. [Content Brief][3]. Lin SK, et al. Aripiprazole and dehydroaripiprazole plasma concentrations and clinical
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CAS:1346604-19-0|Diacetolol-d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Diacetolol-d7 is a deuterium labeled Diacetolol. Diacetolol is the major metabolite of Acebutolol. Diacetolol is a β-adrenoceptor blocking and anti-arrhythmic agent[1].IC50 & Target：β adrenergic receptor分子量：315.42Formula：C16H17D7N2O4CAS 号：1346604-19-0非标记 CAS：22568-64-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (522 KB)产品使用指南 (1538 KB)参考文献[1]. Basil B, et al. Pharmacological properties of diacetolol (M & B 16,942), a major metabolite of acebutolol. Eur J Pharmacol. 1982 May 7;80(1):47-56. [Content Brief]
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