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CAS:1216494-11-9|Rabeprazole-d3 sodium，LY307640-d3 sodium
作者：德尔塔生物 日期：2025-07-08
生物活性：Rabeprazole-d3 (sodium)mis the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Rabeprazole-d3 sodium 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：384.44Formula：C18H17D3N3NaO3SCAS 号：1216494-11-9非标记 CAS：171440-19-0中文名称
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CAS:1217686-68-4|ABT-737-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：ABT 737-d8 is the deuterium labeled ABT-737. ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research[1][2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.ABT-737-d8 相关抗体:Mouse IgG Isotype Control6X His-tag (C-terminal) Antibody (YA860)DYKDDDDK Tag (FLAG) AntibodyGFP AntibodyMyc-tag AntibodyHA tag Antibody (YA856)GST-Tag Antibody HRP ConjugatedV5-tag AntibodyCollagen I alpha 2 AntibodyRabbit IgG Isotype Control6X His Tag (C-terminal) AntibodyHis Tag Antibody (HRP) (YA877)HA Tag Antibody (HRP) (YA876)EYFP Tag Antibody (YA872)HSV Tag Antibody (YA878)MBP Tag Antibody (YA879)RFP Tag Antibody (YA882)S Tag Antibody (YA883)SRT Tag Antibody (YA884)Strep-Tag II Antibody (YA885)TAP Tag Antibody (YA887)Collagen II AntibodyCollagen III AntibodyCollagen X AntibodyCollagen IV AntibodyCollagen I AntibodyCollagen VI alpha 1/2/3 Antibody (YA2637)AmCyan Tag Antibody (YA864)DsbA Tag Antibody (YA868)E2 Tag A
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CAS:2140301-99-9|Deltamethrin-d5，Decamethrin-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Deltamethrin-d5 is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Deltamethrin-d5 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：510.23Formula：C22H14D5Br2NO3CAS 号：2140301-99-9非标记 CAS：52918-63-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (15
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CAS:71258-23-6|Benzyl alcohol-d7，Benzenemethanol-d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Benzyl alcohol-d7 is the deuterium labeled Benzyl alcohol. Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Benzyl alcohol-d7 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：115.18Formula：C7HD7OCAS 号：71258-23-6非标记 CAS：100-51-6性状：液体颜色：Colorless to light yellow中文名称：苯甲醇 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Pure form-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 99.56%参考文献[1]. Russak EM, et al. Impact of Deuterium Substituti
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CAS:1329799-64-5|Piracetam-d8，吡拉西坦 d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Piracetam-d8 (UCB-6215-d8) is the deuterium labeled Piracetam. Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Piracetam-d8 相关抗体:PSD95 AntibodyNMDAR1 AntibodyNMDAR2A AntibodyIonotropic Glutamate Receptor 2 Antibody (YA1143)GRM5 Antibody (YA1509)Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081)NR2E1 Antibody (YA2648)NR2F2 Antibody (YA1223)KA1 Antibody (YA1879)GRIK2 Antibody (YA2705)PSD93 Antibody (YA3187)分子量：150.21Formula：C6H2D8N2O2CAS 号：1329799-64-5非标记 CAS：7491-74-9中文名称：吡拉西坦 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mingeot-Leclercq, M.P., et al., Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Abeta C-terminal fragment. Biochi
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CAS:2748541-85-5|Flavoxate-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Flavoxate-d5 is deuterium labeled Flavoxate.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Flavoxate-d5 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)PDE1B Antibody (YA1553)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)CRCP Antibody (YA3350)Muscarinic Acetylcholine receptor M3 AntibodyAnnexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)PDE4D Antibody (YA1714)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)Muscarinic Acetylcholine Receptor M2 Antibody (YA2610)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)分子量：396.49Formula：C24H20D5NO4CAS 号：2748541-85-5非标记 CAS：15301-69-6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)
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CAS:1219803-67-4|Stavudine-d4，司他夫定 d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Stavudine-d4 is the deuterium labeled Stavudine. Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis[1][2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Stavudine-d4 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP AntibodyNLRP3 Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyNLRP3 AntibodyAIF Antibody (YA636)ALIX AntibodyCD4 AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 Antibody分子量：228.24Formula：C10H8D4N2O4CAS 号：1219803-67-4非标记 CAS：3056-17-5中文名称：司他夫定 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under t
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CAS:1246819-84-0|Dovitinib-d8，多韦替尼 d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Dovitinib-d8 is the deuterium labeled Dovitinib. Dovitinib (CHIR-258) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/FGFR3, VEGFR1/VEGFR2/VEGFR3 and PDGFRα/PDGFRβ, respectively[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Dovitinib-d8 相关抗体:FGFR2/CD332 Antibodyc-Kit Antibody (YA502)Phospho-PDGFR beta (Y740) AntibodyVEGF Receptor 2 Antibody (YA014)FGFR1 AntibodyFGFR1 Oncogene Partner AntibodyFGFR2 AntibodyFGFR3 AntibodyPDGFR alpha AntibodyFGF2 AntibodyM-CSF AntibodyVEGF Receptor 1 AntibodyVEGFA AntibodyCSF-1R Antibody (YA1299)VEGF Receptor2 Antibody FGF1 Antibody (YA1430)PDGF B Antibody (YA1556)FGFR4 Antibody (YA1588)PLGF Antibody (YA1812)PDGFR beta Antibody (YA1925)VEGFD Antibody (YA2385)FGF19 Antibody (YA2672)TACC3 Antibody (YA2921)Phospho-PDGFR beta (Tyr740) Antibody (YA3062)FGF21 Antibody (YA3276)G-CSF Antibody (YA3307)c-Kit AntibodySCF AntibodyPGF Antibody (YA1434)Neuropilin 1 Antibody (YA1831)分子量：400.48Formula：C21H13D8FN6OCAS 号：1246819-84-0非标记 CAS：405169-16-6中文名称：多韦替尼 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended cond
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CAS:1398065-50-3|Terconazole-d4，R42470-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Terconazole-d4 is the deuterium labeled Terconazole. Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Terconazole-d4 相关抗体:SDHA Antibody分子量：536.49Formula：C26H27D4Cl2N5O3CAS 号：1398065-50-3非标记 CAS：67915-31-5性状：固体颜色：White to off-white中文名称：特康唑 d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:2713301-45-0|Ibudilast-d7，异丁司特 d7
作者：德尔塔生物 日期：2025-07-08
生物活性：Ibudilast-d7 is the deuterium labeled Ibudilast. Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ibudilast-d7 相关抗体:PDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)PDE4D Antibody (YA1714)分子量：237.35Formula：C14H11D7N2OCAS 号：2713301-45-0非标记 CAS：50847-11-5中文名称：异丁司特 d7运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (540 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mizuno T, et al. Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia. Neuropharmaco
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CAS:1219794-90-7|Valdecoxib-d3，SC 65872-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Valdecoxib-d3 is the deuterium labeled Valdecoxib. Valdecoxib is a highly potent and selective inhibitor of COX-2, with IC50s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Valdecoxib-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCOX2 AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)COX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin Antibody分子量：317.38Formula：C16H11D3N2O3SCAS 号：1219794-90-7非标记 CAS：181695-72-7中文名称：伐地考昔 d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Shee
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CAS:1794760-31-8|Roflumilast-d4 N-Oxide，罗氟司特 d4 （N 氧化物
作者：德尔塔生物 日期：2025-07-08
生物活性：Roflumilast-d4 N-Oxide is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Roflumilast-d4 N-Oxide 相关抗体:Acetyl CoA synthetase AntibodyPDE1B Antibody (YA1553)PDE4B Antibody (YA2932)PDE2A Antibody (YA2989)PDE4D Antibody (YA1714)分子量：423.23Formula：C17H10D4Cl2F2N2O4CAS 号：1794760-31-8非标记 CAS：292135-78-5性状：固体颜色：White to off-white中文名称：罗氟司特 d4 （N 氧化物）运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1426173-20-7|Cabergoline-d5，FCE-21336-d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Cabergoline-d5 is the deuterium labeled Cabergoline. Cabergoline is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively)[1][2].IC50 & Target：D3 ReceptorD2 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cabergoline-d5 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：456.64Formula：C26H32D5N5O2CAS 号：1426173-20-7非标记 CAS：81409-90-7中文名称：卡麦角林 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271. [Content Brief][3]. Jefferson
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CAS:1189985-02-1|Glyburide-d11，格列本脲 d11
作者：德尔塔生物 日期：2025-07-08
生物活性：Glyburide-d11 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity[1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR)[3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability[4]. Glibenclamide can induce autophagy[5].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Glyburide-d11 相关抗体:Parkin AntibodyMCU AntibodyATP1A1 AntibodyCalumenin Antibody (YA813)Mitofusin 2 AntibodyP Glycoprotein AntibodyLIAS AntibodyNDUFS8 Antibody (YA1352)TOMM20 Antibody (YA1380)NUDT9 Antibody (YA1453)MRP1 Antibody (YA1583)CPS1 Antibody (YA1661)Complex III Subunit 5 Antibody (YA1865)NDUFB8 Antibody (YA1947)MFF Antibody (YA2012)NDUFS4 Antibody (YA2072)MT ND1 Antibody (YA2089)Mitochondrial Fission 1 Protein Antibody (YA2098)Cyclophilin 40 Antibody (YA2099)TIMM44 Antibody (YA2207)NDUFS1 Antibody (YA2535)CLPX Antibody (YA2814)LGI1 Antibody (YA2885)MTCO2 Antibody (YA3254)Mitochondrial Ferritin Antibody
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CAS:958293-77-1|(±-Naproxen-d3-1，(Rac-Naproxen-d3-1 (α-methyl-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：(±)-Naproxen-d3-1 is the deuterium labeled (±)-Naproxen[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(±)-Naproxen-d3-1 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量：233.28Formula：C14H11D3O3CAS 号：958293-77-1非标记 CAS：23981-80-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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