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CAS:951385-68-5|Sildenafil-d8，UK-92480-d8
作者：德尔塔生物 日期：2025-07-08
生物活性：Sildenafil-d8 is the deuterium labeled Sildenafil. Sildenafil (UK-92480) is a potent phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.22 nM[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Sildenafil-d8 相关抗体:ERK1/2 AntibodyE-Cadherin Antibody (YA470)Fatty Acid Synthase Antibody (YA766)DYKDDDDK Tag (FLAG) AntibodyGAPDH AntibodyGFP Antibodyp53 Antibody (YA250)RUNX2 AntibodyFerritin Heavy Chain AntibodyCOX2 AntibodyCtip2 AntibodyCyclin D1 Antibody (YA485)Cytochrome C Antibodyc-Myc AntibodyCyclin E1 AntibodyAIF Antibody (YA636)ALIX AntibodyCNPase AntibodyCortactin AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCyclin A2 AntibodyCyclin B1 Antibody (YA486)DR5 AntibodyDrosha AntibodyE-Cadherin Antibody (YA778)EEA1 AntibodyEpCAM Antibody (YA772)Fatty Acid Synthase AntibodyFIP200 Antibody分子量：482.63Formula：C22H22D8N6O4SCAS 号：951385-68-5非标记 CAS：139755-83-2中文名称：西地那非 d8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmaco
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CAS:1346617-19-3|Levamlodipine-d4，左旋氨氯地平-d4; (S-Amlodipine-d4; Levoamlodipine-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Levamlodipine-d4 is the deuterium labeled Levamlodipine. Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Levamlodipine-d4 相关抗体:Annexin VI AntibodyCalbindin AntibodyCalreticulin AntibodyCardiac Troponin I/TNNC1 AntibodySCGN Antibody (YA1167)RAMP1 Antibody (YA1818)Annexin V Antibody (YA1829)Striatin 4 Antibody (YA2088)Fibulin 5 Antibody (YA2448)RASGRP1 Antibody (YA2546)Fibulin 1 Antibody (YA2831)EFEMP1 Antibody (YA2883)CRCP Antibody (YA3350)Annexin VII Antibody (YA1138)Parvalbumin Antibody (YA1249)Annexin IV Antibody (YA1921)SERCA2 ATPase Antibody (YA1931)Stromal Interaction Molecule 1 Antibody (YA2092)SERCA1 ATPase Antibody (YA2157)TrpV5 Antibody (YA2284)NCX1 Antibody (YA2331)Scramblase 1 Antibody (YA2419)CAB39 Antibody (YA2761)CUG BP1 Antibody (YA2806)C10orf63 Antibody (YA2894)ITPK1 Antibody (YA3125)ORAI3 Antibody (YA3128)ORAI1 Antibody (YA3157)CREB Regulated Transcription Coactivator 2 Antibody (YA3279)分子量：412.90Formula：C20H21D4ClN2O5CAS 号：1346617-19-3非标记 CAS：103129-82-4性状：固体颜色：White to off-white中
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CAS:1794756-15-2|Amisulpride-d5 N-Oxide，氨磺必利 d5（N 氧化物
作者：德尔塔生物 日期：2025-07-08
生物活性：Amisulpride-d5 N-Oxide is the deuterium labeled Amisulpride. Amisulpride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively[1][2].IC50 & Target：D3 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Amisulpride-d5 N-Oxide 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：390.51Formula：C17H22D5N3O5SCAS 号：1794756-15-2非标记 CAS：71676-01-2中文名称：氨磺必利 d5（N 氧化物）运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Schoemaker H, et al. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther. 1997 Jan;280(1):83-97. [Content Brief][3].
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CAS:1216626-17-3|Amisulpride-d5，氨磺必利 d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Amisulpride-d5 is the deuterium labeled Amisulpride. Amisulpride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively[1][2].IC50 & Target：D3 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Amisulpride-d5 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量：374.51Formula：C17H22D5N3O4SCAS 号：1216626-17-3非标记 CAS：71675-85-9性状：固体颜色：White to off-white中文名称：氨磺必利 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1215358-58-9|Bilastine-d6，比拉斯汀 d6
作者：德尔塔生物 日期：2025-07-08
生物活性：Bilastine-d6 is the deuterium labeled Bilastine. Bilastine is a selective histamine H1 receptor antagonist used for treatment of allergic rhinoconjunctivitis and urticaria[1][2].IC50 & Target：H1 Receptor体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Bilastine-d6 相关抗体:ADGRE1 (F4/80) Antibody (YA002)ADGRE1 (F4/80) Antibody (YA920)分子量：469.65Formula：C28H31D6N3O3CAS 号：1215358-58-9非标记 CAS：202189-78-4性状：固体颜色：White to off-white中文名称：比拉斯汀 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1189656-64-1|4'-Hydroxy diclofenac-13C6，4′-羟基双氯芬酸-13C6
作者：德尔塔生物 日期：2025-07-08
生物活性：4'-Hydroxy diclofenac-13C6 is the 13C labeled 4'-Hydroxy diclofenac[1]. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.4'-Hydroxy diclofenac-13C6 相关抗体:FMO3 Antibody (YA1992)分子量：318.10Formula：C813C6H11Cl2NO3CAS 号：1189656-64-1非标记 CAS：64118-84-9中文名称：4′-羟基双氯芬酸-13C6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. J Shimamoto, et al. Lack of Differences in Diclofenac (A Substrate for CYP2C9) Pharmacokinetics in Healthy Volunteers With Respect to the Single CYP2C9*3 Allele. Eur J Clin Pharmacol. 2000 Apr;56(1):65-8. [Content Brief][3]. Hidetaka Kamimura, et al. Formation of the Accumulative Human Metabolite and Human-Specific Glutathione Conjugate of Diclofen
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CAS:7325-16-8|Glycerol-d3，甘油-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Glycerol-d3 is the deuterium labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Glycerol-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：95.11Formula：C3H5D3O3CAS 号：7325-16-8非标记 CAS：56-81-5中文名称：甘油-d3； 丙三醇-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitu
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CAS:1228077-86-8|L-Lysine-13C6 hydrochloride，赖氨酸盐酸盐-13C6
作者：德尔塔生物 日期：2025-07-08
生物活性：L-Lysine-13C6 hydrochloride is the 13C labeled L-Lysine hydrochloride[1]. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health[2][3][4].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.L-Lysine-13C6 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)S100A10 Antibody (YA675)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 Antibody分子量：188.60Formula：13C6H15ClN2O2CAS 号：1228077-86-8非标记 CAS：657-27-2性状：固体颜色：White to off-white中文名称：赖氨酸盐酸盐-13C6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed st
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CAS:2749427-92-5|7-Desmethyl-agomelatine-d3，7-去甲基阿戈美拉汀杂质5-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：7-Desmethyl-agomelatine-d3 is a deuterium labeled 7-Desmethyl-agomelatine. 7-Desmethyl-agomelatine is a metabolite of Agomelatine[1].分子量：232.29Formula：C14H12D3NO2CAS 号：2749427-92-5非标记 CAS：152302-45-9性状：固体颜色：White to off-white中文名称：7-去甲基阿戈美拉汀杂质5-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:1079774-23-4|3-Hydroxy agomelatine-d3，3-羟基阿戈美拉汀杂质7-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：3-Hydroxy agomelatine-d3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM[1].IC50 & Target[1]：5-HT2C Receptor3.2 μM (IC50)5-HT2C Receptor1.8 μM (Ki)分子量：262.32Formula：C15H14D3NO3CAS 号：1079774-23-4非标记 CAS：166526-99-4性状：固体颜色：Off-white to light yellow中文名称：3-羟基阿戈美拉汀杂质7-d3运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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CAS:911392-43-3|Zearalenone-13C18，玉米烯酮-13C18; Mycotoxin F2-13C18; Toxin F2-13C18
作者：德尔塔生物 日期：2025-07-08
生物活性：Zearalenone-13C18 (Mycotoxin F2-13C18; Toxin F2-13C18) is the 13C labeled Zearalenone (HY-103447)[1]. Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts[2][3].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：336.23Formula：13C18H22O5CAS 号：911392-43-3非标记 CAS：17924-92-4性状：液体颜色：Colorless to light yellow中文名称：玉米烯酮-13C18； 玉米赤霉烯酮-13C18；F-2 毒素-13C18运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Solution, -20°C, 2 years
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CAS:1840942-13-3|C16 Ceramide-d7 (d16:1,C16:0
作者：德尔塔生物 日期：2025-07-08
生物活性：C16 Ceramide-d7 (d16:1,C16:0) is the deuterium labeled C16 Ceramide (d16:1,C16:0)[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：544.94Formula：C34H60D7NO3CAS 号：1840942-13-3非标记 CAS：123065-37-2性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：-20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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CAS:1426173-90-1|Cefaclor-d5，头孢克洛 d5
作者：德尔塔生物 日期：2025-07-08
生物活性：Cefaclor-d5 is the deuterium labeled Cefaclor. Cefaclor is an effective antibiotic agent, and specifically binds to penicillin-binding protein 3 (PBP 3)[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Cefaclor-d5 相关抗体:MRP2 AntibodyElongation factor 2 Antibody (YA962)Elongation factor 2 Antibody (YA964)PU.1/SPI1 Antibody (YA1116)Sulfadimidine Antibody (YA906)Elongation factor 2 Antibody (YA963)Anthrax Protective gen Antibody (YA1060)Elongation factor 1 gamma Antibody (YA2004)Pulmonary Surfactant Associated Protein D Antibody (YA2107)Cathelicidin Antibody (YA2380)Elongation Factor Ts Antibody (YA2524)Elongation Factor 1A2 Antibody (YA2879)BPI Antibody (YA3068)MetRS Antibody (YA3196)分子量：372.84Formula：C15H9D5ClN3O4SCAS 号：1426173-90-1非标记 CAS：53994-73-3性状：固体颜色：White to off-white中文名称：头孢克洛 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： ≥97.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Chambers HF, et al. Characterization of penicilli
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CAS:1093951-85-9|Deupirfenidone-d3，吡非尼酮-d3; LYT-100; AMR69-d3
作者：德尔塔生物 日期：2025-07-08
生物活性：Deupirfenidone-d3-d3 is the deuterium labeled Pirfenidone (HY-B0673)[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.体内研究(In Vivo)Administration of Pirfenidone (300 mg/kg/day) for 4 wk. Pirfenidone significantly attenuates the score when administered in Bleomycin (BLM)-treated mice (P
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CAS:2733561-44-7|Lumacaftor-d4，鲁玛卡托-d4; VX-809-d4; VRT 826809-d4
作者：德尔塔生物 日期：2025-07-08
生物活性：Lumacaftor-d4 is the deuterium labeled Lumacaftor (HY-13262)[1].体外研究(In Vitro)：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.体内研究(In Vivo)Oral dosing of 1 mg/kg Lumacaftor in male Sprague-Dawley rats results in a Cmax of 2.4±1.3 μM with a t1/2 of 7.7±0.4 h (mean±SD; n=3), indicating that that Lumacaftor is orally bioavailable and able to reach plasma levels that significantly exceeded EC50s for F508del-CFTR correction[2].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：456.43Formula：C24H14D4F2N2O5CAS 号：2733561-44-7非标记 CAS：936727-05-8性状：固体颜色：White to off-white中文名称：鲁玛卡托-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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