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「同位素标记抑制剂」CAS:1330265-04-7|Hypoxanthine-13C2,15N

「同位素标记抑制剂」CAS:1330265-04-7|Hypoxanthine-13C2,15N

作者:德尔塔生物 日期:2025-06-13

生物活性:Hypoxanthine-13C2,15N is a 15N-labeled and 13C-labled DL-Cystine[1].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[75]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Hypoxanthine-13C2,15N 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:139.09Formula:C313C2H4N315NOCAS 号:1330265-04-7非标记 CAS:68-94-0性状:固体颜色:White to yellow中文名称:次黄嘌呤-13C2,15N运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: ≥91.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]

「同位素标记抑制剂」CAS:85806-18-4|delta-Valerobetaine-d9 chloride

「同位素标记抑制剂」CAS:85806-18-4|delta-Valerobetaine-d9 chloride

作者:德尔塔生物 日期:2025-06-13

生物活性:delta-Valerobetaine-d9 chloride is the deuterium labeled delta-Valerobetaine (HY-114202)[1]. delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO)[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.delta-Valerobetaine-d9 chloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:204.74Formula:C8H9D9ClNO2CAS 号:85806-18-4非标记 CAS:6778-33-2性状:固体颜色:White to off-white运输条件:Room temperature in continental US; may vary elsewhere.储存方式:-20°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

「同位素标记抑制剂」CAS:1356019-94-7|Levomefolic acid-13C,d3

「同位素标记抑制剂」CAS:1356019-94-7|Levomefolic acid-13C,d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Levomefolic acid-13C,d3 is the deuterium labeled Levomefolic acid (HY-14781)[1]. Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Levomefolic acid-13C,d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyCtip2 AntibodyMETTL3 AntibodyRb AntibodyPhospho-Rb (Ser807) AntibodyTSG101 AntibodyRPA32 Antibody (YA679)Alkaline Phosphatase AntibodyCalnexin Antibody (YA573)Catalase Antibody (YA552)Catalase Antibody (YA811)CDT1 AntibodyDNA-PKcs/PRKDC AntibodyHes1 AntibodyJunB AntibodyLamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyLIN28A AntibodyLin28B AntibodyMCM2 AntibodyNanog AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)分子量:463.47Formula:C1913CH22D3N7O6CAS 号:1356019-94-7非标记 CAS:31690-09-2性状:固体颜色:White to off-white中文名称:5-甲基四氢叶酸-13C,d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

「同位素标记抑制剂」CAS:338976-76-4|3α,7α-Dihydroxycoprostanic acid-d3

「同位素标记抑制剂」CAS:338976-76-4|3α,7α-Dihydroxycoprostanic acid-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:3α,7α-Dihydroxycoprostanic acid-d3 is the deuterium labeled 3α,7α-Dihydroxycoprostanic acid (HY-113097)[1]. 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid[2].体外研究(In Vitro):氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.3α,7α-Dihydroxycoprostanic acid-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:437.67Formula:C27H43D3O4CAS 号:338976-76-4非标记 CAS:17974-66-2性状:固体颜色:White to off-white中文名称:3α,7α-二羟基粪烯酸-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month纯度 & 产品资料纯度: ≥99.0%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharm

「同位素标记抑制剂」CAS:850153-85-4|DL-dithiothreitol-d6

「同位素标记抑制剂」CAS:850153-85-4|DL-dithiothreitol-d6

作者:德尔塔生物 日期:2025-06-13

生物活性:DL-dithiothreitol-d6 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:160.29Formula:C4H4D6O2S2CAS 号:850153-85-4非标记 CAS:3483-12-3性状:固体颜色:White to off-white中文名称:DL-二硫苏糖醇-d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture and light*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

「同位素标记抑制剂」CAS:1173021-86-7|2-Ketoglutaric acid-d6

「同位素标记抑制剂」CAS:1173021-86-7|2-Ketoglutaric acid-d6

作者:德尔塔生物 日期:2025-06-13

生物活性:2-Ketoglutaric acid-d6 is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.2-Ketoglutaric acid-d6 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyMiTF AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)ZAP70 Antibody (YP4051)Asparagine Synthetase AntibodyCalnexin AntibodyCD3 epsilon AntibodyCD3D AntibodyKi67 Antibody (YA001)分子量:152.14Formula:C5D6O5CAS 号:1173021-86-7性状:固体颜色:White to off-white中文名称:α-酮戊二酸-d6运输条件:Room temperature in continental US; may vary elsewhere.储

「同位素标记抑制剂」CAS:74495-69-5|Guaiacol-d3

「同位素标记抑制剂」CAS:74495-69-5|Guaiacol-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Guaiacol-d3 is the deuterium labeled Guaiacol. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Guaiacol has an anti-inflammatory activity[1].分子量:127.16Formula:C7H5D3O2CAS 号:74495-69-5非标记 CAS:90-05-1性状:液体(密度:1.137 g/cm3)颜色:Light yellow to light brown中文名称:愈创木酚-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Pure form-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:185056-83-1|Coumarin-d4

「同位素标记抑制剂」CAS:185056-83-1|Coumarin-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:Coumarin-d4 is the deuterium labeled Coumarin. Coumarin is the primary bioactive ingredient in Radix Glehniae, named Beishashen in China, which possesses many pharmacological activities, including anticancer, anti-inflammation and antivirus activities.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Coumarin-d4 相关抗体:Poliovirus Receptor Antibody (YA2556)分子量:150.17Formula:C9H2D4O2CAS 号:185056-83-1非标记 CAS:91-64-5性状:固体颜色:White to off-white中文名称:香豆素 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1092942-82-9|Imatinib-d8

「同位素标记抑制剂」CAS:1092942-82-9|Imatinib-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:Imatinib-d8 is a deuterium labeled Imatinib (STI571). Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity[1][2].分子量:501.65Formula:C29H23D8N7OCAS 号:1092942-82-9非标记 CAS:152459-95-5性状:固体颜色:White to light yellow中文名称:伊马替尼 d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1242184-43-5|Oseltamivir acid-d3

「同位素标记抑制剂」CAS:1242184-43-5|Oseltamivir acid-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Oseltamivir acid-d3 is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].分子量:287.37Formula:C14H21D3N2O4CAS 号:1242184-43-5非标记 CAS:187227-45-8性状:固体颜色:White to off-white中文名称:奥斯他伟酸 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1132093-70-9|Dasatinib-d8

「同位素标记抑制剂」CAS:1132093-70-9|Dasatinib-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:Dasatinib-d8 is a deuterium labeled Dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.分子量:496.05Formula:C22H18D8ClN7O2SCAS 号:1132093-70-9非标记 CAS:302962-49-8性状:固体颜色:White to off-white中文名称:达沙替尼 d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1173147-91-5|Ofloxacin-d3

「同位素标记抑制剂」CAS:1173147-91-5|Ofloxacin-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Ofloxacin-d3 is the deuterium labeled Ofloxacin[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ofloxacin-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:364.39Formula:C18H17D3FN3O4CAS 号:1173147-91-5非标记 CAS:82419-36-1性状:固体颜色:White to off-white中文名称:氧氟沙星-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1276197-36-4|(Rac)-Atropine-d3

「同位素标记抑制剂」CAS:1276197-36-4|(Rac)-Atropine-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:(Rac)-Atropine-d3 is the deuterium labeled (Rac)-Atropine[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Atropine-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:292.39Formula:C17H20D3NO3CAS 号:1276197-36-4非标记 CAS:51-55-8性状:固体颜色:White to off-white中文名称:阿托品 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1092484-69-9|Fenofibric acid-d6

「同位素标记抑制剂」CAS:1092484-69-9|Fenofibric acid-d6

作者:德尔塔生物 日期:2025-06-13

生物活性:Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fenofibric acid-d6 相关抗体:PPAR alpha AntibodyCOX2 AntibodyPPAR gamma AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyPPAR gamma Antibody (YA122)COX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)PGC1 beta Antibody (YA1411)分子量:324.79Formula:C17H9D6ClO4CAS 号:1092484-69-9非标记 CAS:42017-89-0性状:固体颜色:White to off-white中文名称:非诺贝特酸 d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:222412-82-0|Atorvastatin-d5 hemicalcium

「同位素标记抑制剂」CAS:222412-82-0|Atorvastatin-d5 hemicalcium

作者:德尔塔生物 日期:2025-06-13

生物活性:Atorvastatin-d5 (hemicalcium) is the deuterium labeled Atorvastatin. Atorvastatin hemicalcium is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Atorvastatin-d5 hemicalcium 相关抗体:HMGCS2 AntibodyHMGB1 AntibodyHMGCR AntibodyBaf180 Antibody (YA1176)BANF1 Antibody (YA1740)LEF1 Antibody (YA3164)HMGA1 Antibody (YA1185)HMGA2 Antibody (YA1186)Baf57 Antibody (YA2110)HMGN2 Antibody (YA2839)HMG4 Antibody (YA2992)HMGB2 Antibody (YA2995)HMGCL Antibody (YA3024)分子量:583.71Formula:C33H30D5FN2O5.1/2CaCAS 号:222412-82-0非标记 CAS:134523-03-8性状:固体颜色:White to off-white中文名称:阿托伐他汀 d5 (1/2钙盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)