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「同位素标记抑制剂」CAS:1132093-70-9|Dasatinib-d8

「同位素标记抑制剂」CAS:1132093-70-9|Dasatinib-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:Dasatinib-d8 is a deuterium labeled Dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.分子量:496.05Formula:C22H18D8ClN7O2SCAS 号:1132093-70-9非标记 CAS:302962-49-8性状:固体颜色:White to off-white中文名称:达沙替尼 d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1173147-91-5|Ofloxacin-d3

「同位素标记抑制剂」CAS:1173147-91-5|Ofloxacin-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Ofloxacin-d3 is the deuterium labeled Ofloxacin[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Ofloxacin-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:364.39Formula:C18H17D3FN3O4CAS 号:1173147-91-5非标记 CAS:82419-36-1性状:固体颜色:White to off-white中文名称:氧氟沙星-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1276197-36-4|(Rac)-Atropine-d3

「同位素标记抑制剂」CAS:1276197-36-4|(Rac)-Atropine-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:(Rac)-Atropine-d3 is the deuterium labeled (Rac)-Atropine[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Atropine-d3 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量:292.39Formula:C17H20D3NO3CAS 号:1276197-36-4非标记 CAS:51-55-8性状:固体颜色:White to off-white中文名称:阿托品 d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:1092484-69-9|Fenofibric acid-d6

「同位素标记抑制剂」CAS:1092484-69-9|Fenofibric acid-d6

作者:德尔塔生物 日期:2025-06-13

生物活性:Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM.体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Fenofibric acid-d6 相关抗体:PPAR alpha AntibodyCOX2 AntibodyPPAR gamma AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyPPAR gamma Antibody (YA122)COX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)PGC1 beta Antibody (YA1411)分子量:324.79Formula:C17H9D6ClO4CAS 号:1092484-69-9非标记 CAS:42017-89-0性状:固体颜色:White to off-white中文名称:非诺贝特酸 d6运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Powder:-20°C:3 years,4°C:2 yearsIn solvent:-80°C:6 months,-20°C:1 month

「同位素标记抑制剂」CAS:222412-82-0|Atorvastatin-d5 hemicalcium

「同位素标记抑制剂」CAS:222412-82-0|Atorvastatin-d5 hemicalcium

作者:德尔塔生物 日期:2025-06-13

生物活性:Atorvastatin-d5 (hemicalcium) is the deuterium labeled Atorvastatin. Atorvastatin hemicalcium is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Atorvastatin-d5 hemicalcium 相关抗体:HMGCS2 AntibodyHMGB1 AntibodyHMGCR AntibodyBaf180 Antibody (YA1176)BANF1 Antibody (YA1740)LEF1 Antibody (YA3164)HMGA1 Antibody (YA1185)HMGA2 Antibody (YA1186)Baf57 Antibody (YA2110)HMGN2 Antibody (YA2839)HMG4 Antibody (YA2992)HMGB2 Antibody (YA2995)HMGCL Antibody (YA3024)分子量:583.71Formula:C33H30D5FN2O5.1/2CaCAS 号:222412-82-0非标记 CAS:134523-03-8性状:固体颜色:White to off-white中文名称:阿托伐他汀 d5 (1/2钙盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

「同位素标记抑制剂」Etifoxine-d5

「同位素标记抑制剂」Etifoxine-d5

作者:德尔塔生物 日期:2025-06-13

生物活性:Etifoxine-d5 is the deuterium labeled Etifoxine. Etifoxine, a non-benzodiazepine GABAergic compound, is a positive allosteric modulator of α1β2γ2 and α1β3γ2 subunit-containing GABAA receptors. Etifoxine reveals anxiolytic and anticonvulsant properties in rodents[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Etifoxine-d5 相关抗体:GABARAP AntibodyIP3 Receptor Antibody (YA1596)GABA B Receptor 2 Antibody (YA1733)GABA B Receptor 1 Antibody (YA2418)GAD65 Antibody (YA758)GABA A Receptor alpha 1 Antibody (YA1315)GABA A Receptor beta 2 Antibody (YA1758)GABA Transporter 1 Antibody (YA1795)GAD67 Antibody (YA1807)ABAT Antibody (YA1964)GABA A Receptor alpha 5 Antibody (YA2249)GABA A Receptor beta 1 Antibody (YA2261)BGAT Antibody (YA2741)GABARAPL2 Antibody (YA2882)分子量:305.81Formula:C17H12D5ClN2OCAS 号:1346598-10-4非标记 CAS:21715-46-8中文名称:艾替伏辛-d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacothe

「同位素标记抑制剂」(rac)-Dobutamine-d6 hydrochloride

「同位素标记抑制剂」(rac)-Dobutamine-d6 hydrochloride

作者:德尔塔生物 日期:2025-06-13

生物活性:(rac)-Dobutamine-d6 (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion[1][2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(rac)-Dobutamine-d6 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量:343.88Formula:C18H18D6ClNO3CAS 号:1246818-96-1非标记 CAS:49745-95-1中文名称:多巴酚丁胺盐酸盐 d6 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (530 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Tuttle RR, et al. Dobutamine: development of a new catecholamine to selectively increase cardiac contractility.

「同位素标记抑制剂」(rac)-Dobutamine-d4 hydrochloride

「同位素标记抑制剂」(rac)-Dobutamine-d4 hydrochloride

作者:德尔塔生物 日期:2025-06-13

生物活性:(rac)-Dobutamine-d4 (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion[1][2][3][4].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(rac)-Dobutamine-d4 hydrochloride 相关抗体:ADRB2 AntibodySalbutamol Antibody (YA901)Clenbuterol Antibody (YA904)alpha 1a Adrenergic Receptor Antibody (YA2059)分子量:341.87Formula:C18H20D4ClNO3CAS 号:1246815-74-6非标记 CAS:49745-95-1中文名称:多巴酚丁胺盐酸盐 d4 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (529 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Tuttle RR, et al. Dobutamine: development of a new catecholamine to selectively increase cardiac contractility.

「同位素标记抑制剂」Nelfinavir-d3

「同位素标记抑制剂」Nelfinavir-d3

作者:德尔塔生物 日期:2025-06-13

生物活性:Nelfinavir-d3 (AG1341-d3) is the deuterium labeled Nelfinavir. Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor (Ki=2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent[1][2][3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Nelfinavir-d3 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:570.80Formula:C32H42D3N3O4SCAS 号:1217629-70-3非标记 CAS:159989-64-7中文名称:奈非那韦-d3; 那非那韦-d3运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Mondal D, et al. Nelfinavir suppresses signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones. Ochsner J. 2013 Spring;13(1):76-90. [Content Brief][3]. Gills JJ, et al. Nelfinavir, A lead HIV protease inhibitor,

「同位素标记抑制剂」Carisbamate-d4

「同位素标记抑制剂」Carisbamate-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:Carisbamate-d4 is the deuterium labeled Carisbamate[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:219.66Formula:C9H6D4ClNO3CAS 号:1292841-50-9非标记 CAS:194085-75-1运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (518 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

「同位素标记抑制剂」Volinanserin-d4 hydrochloride

「同位素标记抑制剂」Volinanserin-d4 hydrochloride

作者:德尔塔生物 日期:2025-06-13

生物活性:Volinanserin-d4 (hydrochloride) is the deuterium labeled Volinanserin hydrochlorid. Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity[1][2].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Volinanserin-d4 hydrochloride 相关抗体:MTNR1A Antibody分子量:413.95Formula:C22H25D4ClFNO3CAS 号:1217617-73-6非标记 CAS:139290-65-6中文名称:氟利色林 d4 (盐酸盐)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (528 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Sorensen SM, et al. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. J Pharmacol Exp Ther. 1993 Aug;266(2):684-91. [Content Brief][3]. Ardayfio PA, et al. The 5-hydroxytryptamine2A receptor ant

「同位素标记抑制剂」Tasimelteon-d5

「同位素标记抑制剂」Tasimelteon-d5

作者:德尔塔生物 日期:2025-06-13

生物活性:Tasimelteon-d5 is the deuterium labeled Tasimelteon. Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24)[1][2].IC50 & Target:MT2体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量:250.35Formula:C15H14D5NO2CAS 号:1962124-51-1非标记 CAS:609799-22-6中文名称:他司美琼 d5运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Christian Lavedan, et al. Tasimelteon: a selective and unique receptor binding profile. Neuropharmacology. 2015 Apr;91:142-7. [Content Brief][3]. Keating GM, et al. Tasimelteon: A Review in Non-24-Hour Sleep-Wake Disorder in Totally Blind Individuals. CNS Drugs. 2016 Mar 22. [Content Brief]

「同位素标记抑制剂」Firocoxib-d4

「同位素标记抑制剂」Firocoxib-d4

作者:德尔塔生物 日期:2025-06-13

生物活性:Firocoxib-d4 (ML 1785713-d4) is the deuterium labeled Firocoxib. Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects[1].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Firocoxib-d4 相关抗体:COX2 AntibodyCOX IV AntibodyCOX2/Cyclooxygenase 2 AntibodyCOX IV Antibody (YA867)Cyclooxygenase 1 Antibody (YA2537)Cyclooxygenase 2 Antibody (YA2541)分子量:340.43Formula:C17H16D4O5SCAS 号:1325700-11-5非标记 CAS:189954-96-9中文名称:非罗考昔 d4运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (535 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Steagall PV, et al. Evaluation of the adverse effects of oral firocoxib in healthy dogs. J Vet Pharmacol Ther. 2007 Jun;30(3):218-23. [Content Brief][3]. Stock ML, et al. Pharmacokinetics of firocoxib in preweaned calve

「同位素标记抑制剂」Lopinavir-d8

「同位素标记抑制剂」Lopinavir-d8

作者:德尔塔生物 日期:2025-06-13

生物活性:Lopinavir-d8 (ABT-378-d8) is the deuterium labeled Lopinavir. Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity[1][2]. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM[3].体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Lopinavir-d8 相关抗体:CD4 AntibodyTARBP2 Antibody (YA1433)SAMHD1 Antibody (YA1542)SV40 T Antigen Antibody (YA3256)CLEC12A Antibody (YA1419)Tat SF1 Antibody (YA2886)分子量:636.85Formula:C37H40D8N4O5CAS 号:1224729-35-4非标记 CAS:192725-17-0中文名称:洛匹那韦-d8运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (534 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Cvetkovic RS, et al. Lopinavir/ritonavir: a review of its use in the management of HIV infection. Drugs. 2003;63(8):769-802. [Conte

「同位素标记抑制剂」Haloperidol-d4 N-Oxide

「同位素标记抑制剂」Haloperidol-d4 N-Oxide

作者:德尔塔生物 日期:2025-06-13

生物活性:Haloperidol-d4 N-Oxide is the deuterium labeled Haloperidol. Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic[1][2].IC50 & Target:D2 Receptor体外研究(In Vitro):Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Haloperidol-d4 N-Oxide 相关抗体:DRD2 AntibodyDopamine Receptor D3 Antibody (YA1742)DOPA Decarboxylase Antibody (YA2428)Dopamine Receptor D1 Antibody (YA3270)Torsin 1A Antibody (YA2935)PITX3 Antibody (YA2974)HMBS Antibody (YA3061)分子量:395.89Formula:C21H19D4ClFNO3CAS 号:1246815-56-4非标记 CAS:52-86-8中文名称:氟哌啶醇 d4(N 氧化物)运输条件:Room temperature in continental US; may vary elsewhere.储存方式:Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.  [Content Brief][2]. Furuta Y, et al. Effects of enzyme inhibitors of catecholamine metabolism and of haloperidol on the pancreatic secretion induced by L-DOPA and by dopamine in dogs. Br J Pharmacol. 1973 Jan;47(1):77-84 [Content Brief][3]. Shah NS, et al. Effects of chlorpromaz