【产品介绍】：

产品名称 PR-619 英文名称 PR-619 规格或纯度 ≥98% 别名 PR619 英文别名 2,6-Diamino-3,5-dithiocyanopyridine;PR 619;PR619; Thiocyanic acid C,C′-(2,6-diamino-3,5-pyridinediyl) ester; 2,6-Diaminopyridine-3,5-bis(thiocyanate) 运输条件 超低温冰袋运输 生化机理 PR-619 is a cell permeable broad spectrum deubiquitylating enzymes (DBUs) inhibitor. PR-619 induces the accumulation of polyubiquitylated proteins in cells without directly affecting proteasome activity.Cell-permeable, non-selective and reversible DUB inhibitor (IC 50 values are 5 to 20 μM). Induces polyubiquitinated protein accumulation in cells without directly affecting proteasome activity. Activates autophagy.CAS编号 2645-32-1 溶解性 25°C: DMSO 45 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL 储存温度 -20°C储存 MDL号 MFCD00830384 分子量 223.28 分子式 C7H5N5S2 PubChem CID 2817763