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新型纳米磁共振成像(MRI)造影剂/核磁共振纳米灯/顺磁性MRI造影剂技术
发布时间:2021-04-02     作者:wyf   分享到:

新型纳米磁共振成像(MRI)造影剂/核磁共振纳米灯/顺磁性MRI造影剂技术

全新的纳米磁共振成像(MRI)造影剂技术,能够大幅度提升医学图像的可识别度。动物实验结果表明,使用该造影剂,实验鼠异常组织的亮度是周围健康组织亮度的10倍。新的造影剂技术具有选择性,形成的核磁共振图像对癌症等特定代谢的标志物敏感。

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纳米造影剂基于磁谐振技术,主要由两种磁性材料组成,包括“开关材料”(磁性纳米颗粒)和“显影材料”(顺磁性MRI造影剂),两种材料之间的距离不同,核磁共振图像的亮度也不同。两种材料之间的临界距离大于7纳米时,开关材料对显影材料的影响消失,顺磁性造影剂在MRI图像上充分显影,此时相当于开关的“开”;当二者距离小于7纳米时,顺磁性显影材料在MRI图像上的状态则是“关”。

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研究人员制造了一种足以探测实验鼠体内癌症的造影剂。造影剂使用一种能够被癌症代谢产物MMP-2酶切断的生物材料连接“开关材料”和“显影材料”,令两种材料之间的初始距离低于7纳米。显影剂注入实验鼠组织后,如果组织中存在癌变,两种材料之间的连接将会被MMP-2酶切断,导致两种材料分离,MRI图像会将病灶区域显示为高亮度。

 

使用纳米造影剂技术,MRI检查能够显示肿瘤的存在和具体分布,还可以通过图像揭示癌组织中MMP-2酶的浓度,获得癌变分期等进一步信息。

齐岳生物产品供应:

活体荧光造影剂

Sulfo-CY7(Cyanine7) NHSester活体荧光造影剂

Sulfo-CY7-NHS,Sulfo-Cyanine7.5NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

sulfo-CY7(Cyanine7) maleimide活体荧光造影剂

sulfo-CY7-MAL,sulfo-Cyanine7.5maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) dicarboxylicacid活体荧光造影剂

Sulfo-Cyanine7.5dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) carboxylicacid活体荧光造影剂

Sulfo-Cy7COOHSulfo-Cyanine7.5carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) azide活体荧光造影剂

Sulfo-CY7/N3,Sulfo-Cyanine7.5azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) alkyne活体荧光造影剂

Sulfo-CY7-alkyne,Sulfo-Cyanine7.5alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) tetrazine活体荧光造影剂

Sulfo-Cyanine7tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) NHSester活体荧光造影剂

Sulfo-Cyanine7NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) maleimide活体荧光造影剂

Sulfo-Cyanine7maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

sulfo-CY7(Cyanine7) dicarboxylicacid活体荧光造影剂

sulfo-Cyanine7dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) carboxylicacid活体荧光造影剂

Sulfo-Cyanine7carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) bis-NHSester活体荧光造影剂

Sulfo-Cyanine7bis-NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) azide活体荧光造影剂

Sulfo-Cyanine7azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) amine活体荧光造影剂

Sulfo-Cyanine7amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

Sulfo-CY7(Cyanine7) alkyne活体荧光造影剂

Sulfo-Cyanine7alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) tetrazine活体荧光造影剂

Cyanine7.5tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) NHSester活体荧光造影剂

Cyanine7.5NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) maleimide活体荧光造影剂

Cyanine7.5maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) hydrazide活体荧光造影剂

Cyanine7.5hydrazide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) carboxylicacid活体荧光造影剂

Cyanine7.5carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7 (Cyanine7) azide活体荧光造影剂

Cyanine7.5azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7 (Cyanine7) azide,10mM/DMSO活体荧光造影剂

Cyanine7.5azide,10mM/DMSO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) amine活体荧光造影剂

Cyanine7.5amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) alkyne活体荧光造影剂

Cyanine7.5alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) tetrazine活体荧光造影剂

Cyanine7tetrazine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) NHSester活体荧光造影剂

Cyanine7NHSester,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) maleimide活体荧光造影剂

Cyanine7maleimide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) hydrazide活体荧光造影剂

Cyanine7hydrazide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) dicarboxylicacid活体荧光造影剂

Cyanine7dicarboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) DBCO活体荧光造影剂

Cyanine7DBCO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) carboxylicacid活体荧光造影剂

Cyanine7carboxylicacid,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) azide活体荧光造影剂

Cyanine7azide,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) azide,10mM/DMSO活体荧光造影剂

Cyanine7azide,10mM/DMSO,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) amine活体荧光造影剂

Cyanine7amine,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

CY7(Cyanine7) alkyne活体荧光造影剂

Cyanine7alkyne,Comparisonofcyanine(Cy)dyesusedinlifescienceaslabelsformolecularbiologyanddiagnostics

 

BDP650/665XNHSester活体荧光造影剂

BDP650/665XNHSester,Borondipyrromethenedyeforfluorescein(516nm)channel-verybrightandphotostablefluorophore.

 

BDP650/665maleimide活体荧光造影剂

BDP650/665maleimide,Borondipyrromethenedyeforfluorescein(515nm)channel-verybrightandphotostablefluorophore.

 

BDP650/665azide活体荧光造影剂

BDP650/665azide,Borondipyrromethenedyeforfluorescein(514nm)channel-verybrightandphotostablefluorophore.

 

BDP650/665alkyne活体荧光造影剂

BDP650/665alkyne,Borondipyrromethenedyeforfluorescein(513nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650XNHSester活体荧光造影剂

BDP630/650XNHSester,Borondipyrromethenedyeforfluorescein(512nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650tetrazine活体荧光造影剂

BDP630/650tetrazine,Borondipyrromethenedyeforfluorescein(511nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650maleimide活体荧光造影剂

BDP630/650maleimide,Borondipyrromethenedyeforfluorescein(510nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650hydrazide活体荧光造影剂

BDP630/650hydrazide,Borondipyrromethenedyeforfluorescein(509nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650carboxylicacid活体荧光造影剂

BDP630/650carboxylicacid,Borondipyrromethenedyeforfluorescein(508nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650azide活体荧光造影剂

BDP630/650azide,Borondipyrromethenedyeforfluorescein(507nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650amine活体荧光造影剂

BDP630/650amine,Borondipyrromethenedyeforfluorescein(506nm)channel-verybrightandphotostablefluorophore.

 

BDP630/650alkyne活体荧光造影剂

BDP630/650alkyne,Borondipyrromethenedyeforfluorescein(505nm)channel-verybrightandphotostablefluorophore.

上述产品齐岳生物均可供应,仅用于科研,不可用于人体实验!

wyf 04.02

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